实体器官移植与弓形虫病

doi:10.12140/j.issn.1000-7423.2021.03.015

中国寄生虫学与寄生虫病杂志 ›› 2021, Vol. 39 ›› Issue (3): 386-392.doi: 10.12140/j.issn.1000-7423.2021.03.015

实体器官移植与弓形虫病

黄子芸¹(), 吕芳丽¹^,²^,³^,^*()

1 中山大学中山医学院寄生虫学教研室,广州 510080
2 中山大学热带病防治研究教育部重点实验室,广州 510080
3 广东省媒介生物防控工程技术研究中心,广州 510080

收稿日期:2020-09-21 修回日期:2020-11-19 出版日期:2021-06-30 发布日期:2021-07-05
通讯作者: 吕芳丽
作者简介:黄子芸（1993-）,女,博士研究生,从事寄生虫的感染和免疫机制研究。E-mail： 609797774@qq.com
基金资助:
国家自然科学基金面上项目(81971955);广东省自然科学基金面上项目(2019A1515011667);广东省自然科学基金面上项目(2021A1515012115);中山大学热带病防治研究教育部重点实验室开放基金(2020ZX02);2021年中山大学校级本科教学质量工程项目（中大教务[2021]93号）;2020年中山大学校级本科教学质量工程项目（中大教务[2020]72号）

Solid organ transplantation and toxoplasmosis

HUANG Zi-yun¹(), LV Fang-li¹^,²^,³^,^*()

1 Department of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China
2 Key Laboratory of Tropical Disease of Ministry of Education, Sun Yat-sen University, Guangzhou 510080, China
3 Provincial Engineering Technology Research Center for Biological Vector Control, Guangzhou 510080, China

Received:2020-09-21 Revised:2020-11-19 Online:2021-06-30 Published:2021-07-05
Contact: LV Fang-li
Supported by:
National Natural Science Foundation of China(81971955);Natural Science Foundation of Guangdong Province(2019A1515011667);Natural Science Foundation of Guangdong Province(2021A1515012115);Open Project of Key Laboratory of Tropical Disease Control of Ministry of Education, Sun Yat-sen University(2020ZX02);Undergraduate Teaching Quality Engineering Project of Sun Yat-sen University（SYSU Undergraduate Education [2021]93）;Undergraduate Teaching Quality Engineering Project of Sun Yat-sen University（SYSU Undergraduate Education [2020]72）

摘要/Abstract

摘要：

免疫功能正常的人感染刚地弓形虫（简称弓形虫）后通常是无症状的,但免疫功能低下者感染可能出现严重的临床症状,甚至导致致命的后果。由于器官移植者实体移植器官的多样性、免疫抑制程度的差异性以及弓形虫病发病率相对较低等特点,临床上对器官移植受者弓形虫感染的风险认识不足。因此,本文就实体器官移植受者弓形虫病的临床表现、发病机制、诊断、预防和治疗作一综述,旨在为临床上实体器官移植后的弓形虫病诊治提供参考。

关键词: 弓形虫病, 实体器官移植, 发病机制, 诊断, 预防, 治疗

Abstract:

Toxoplasma gondii infection in immunocompetent people is often asymptomatic, but may lead to severe clinical symptoms in immunocompromised patients, even with fatal consequences. Due to the diversity of solid organ transplants, the degrees of immunosuppression, and the relatively low incidence of toxoplasmosis among organ transplant recipients, the clinical risk of T. gondii infection in organ transplant patients remains poorly understood. Therefore, this paper reviews the clinical manifestations, pathogenesis, diagnosis, prevention, and treatment of toxoplasmosis in solid organ transplant recipients, in order to provide reference for clinical diagnosis and treatment of toxoplasmosis after solid organ transplantation.

Key words: Toxoplasma gondii, Solid organ transplantation, Pathogenesis, Diagnosis, Prevention, Treatment

中图分类号:

R531.8

黄子芸, 吕芳丽. 实体器官移植与弓形虫病[J]. 中国寄生虫学与寄生虫病杂志, 2021, 39(3): 386-392.

HUANG Zi-yun, LV Fang-li. Solid organ transplantation and toxoplasmosis[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2021, 39(3): 386-392.

图/表 1

表1

1980—2020年不同实体器官移植后弓形虫病患者临床资料

病例信息	心脏移植（42例）	肝移植（20例）	肾移植（32例）
年龄/岁	3~64	7~62	14~74
性别	男（19例）,女（10例）,未知（13例）	男（5例）,女（12例）,未知（3例）	男（20例）,女（11例）,未知（1例）
D/R血清学	D⁺/R^-（27例）,D^-/R⁺（1例）, 未知/R^-（11例）,未知/R⁺（1例）, 未知（1例）	D⁺/R^-（7例）,D^-/R⁺（5例）, 未知/R^-（2例）,未知/R⁺（1例）, D⁺/R⁺（4例）,未知（1例）	D⁺/R^-（20例）,D^-/R⁺（2例）,未知/R^-（1例）,未知/R⁺（2例）,D^-/未知（1例）,D⁺/未知（1例）,未知（5例）
预防药物	无（30例）,PY + LKV（5例）,TMP + SMX（2例）,SF（1例）,ATO（1例）,PY + SDZ（1例）	无（10例）,TMP+SMX（4例）,PY + SDZ + LKV（1例）,未知（5例）	无（10例）,TMP + SMX（7例）,SF（2例）,未知（13例）
免疫抑制药物	P（25例）,AZ（16例）,CSA（15例）,ATG（14例）,MMF（6例）,TAC（4例）,MET（4例）	TAC（10例）,MMF（8例）,P（8例）,CSA（5例）,AZ（4例）,MET（4例）,ATG（2例）	CSA（18例）,ATG（14例）,P（12例）,MMF（11例）,AZ（8例）,MET（7例）,TAC（6例）,OKT3（3例）
移植后初始发病天数	5~30 d（15例）,31~90 d（10例）,91~365 d（8例）,2~12年（2例）,未知（7例）	2~30 d（11例）,31~90 d（3例）,91~365 d（3例）,未知（3例）	16 h~30 d（18例）,31~90 d（3例）,91~365 d（6例）,2~11年（5例）
临床症状	发热（19例）,脑炎（8例）,肺炎（8例）,呼吸窘迫（8例）,播散性弓形虫病（8例）,心肌炎（6例）,神经系统症状（6例）,脉络膜视网膜炎（3例）	发热（10例）,巨细胞病毒感染（8例）,肺炎（5例）,神经系统症状（3例）,脑水肿（2例）,败血症（2例）,白细胞减少（2例）	发热（10例）,巨细胞病毒感染（8例）,肺炎（5例）,神经系统症状（3例）,脑水肿（2例）,败血症（2例）,白细胞减少（2例）
发病机制	D⁺传染给R^-（29例）,隐性弓形虫感染活化（4例）,未知（9例）,	D⁺传染给R^-（9例）,隐性弓形虫感染的活化（10例）,未知（1例）	D⁺传染给R^-（20例）,隐性弓形虫感染活化（6例）,食用未煮熟肉类（2例）,未知（4例）,
感染后治疗药物	无（13例）,PY + SDZ（12例）,PY + SDZ + LKV（3例）,TMP + SMX（2例）,CLR + PY（2例）,PY（2例）,PY + SDZ + SF + CLR（1例）,PZA + SDZ + LKV（1例）,TMP + PY + SDZ + SP（1例）,ATO（1例）,未知（4例）	无（6例）,PY + SDZ（3例）,PY + SDZ + LKV（1例）,TMP + SMX（4例）,TMP + SMX + VA + MEM（1例）,CLR + TMP + SMX（1例）,SMX + AZM（1例）,VA+PRL + TZP（1例）,PY（1例）,CAZ + CIP + TEC + FCA（1例）	无（9例）,PY + SDZ（7例）,PY + SDZ + LKV（2例）,TMP + SMX（2例）,CLR + PY（3例）,CLR + TMP + SMX（1例）,SMX（1例）,PY + SDZ + ATO（1例）,VA + PY + CLR + LKV（1例）,CLR + PY + TMP + SMX（1例）,AZM（1例）,未知（3例）
预后	死亡（26例）,存活（16例）	死亡（10例）,存活（10例）	死亡（14例）,存活（17例）,未知（1例）
参考文献	13-17, 30, 32, 37, 39, 40, 44-49	3, 19, 22, 23, 29, 38, 41, 50-58	7, 24-28, 59-71

表1

参考文献 71

[1]	Hill D, Dubey JP. Toxoplasma gondii: transmission, diagnosis and prevention[J]. Clin Microbiol Infect, 2002,8(10):634-640.
[2]	Liu JF, Lv FL. Research progress of pulmonary toxoplasmosis[J]. J Trop Med, 2014,14(4):541-544. (in Chinese)
[2]	( 刘晋锋, 吕芳丽. 肺弓形虫病研究进展[J]. 热带医学杂志, 2014,14(4):541-544.)
[3]	Derouin F, Pelloux H. Prevention of toxoplasmosis in transplant patients[J]. Clin Microbiol Infect, 2008,14(12):1089-1101.
[4]	Izadi M, Jonaidi Jafari N, Mahmoodzadeh Poornaki A, et al. Detection of Toxoplasma gondii from clinical specimens of patients receiving renal transplant using ELISA and PCR[J]. Nephrourol Mon, 2013,5(5):983-987.
[5]	Galvan-Ramírez ML, Rincón Sanchez AR, Bernal Redondo RM. Chapter 10. Diagnostic of opportunistic parasites in liver transplantation[M] //Bruyn O, Peeters S. Parasitology research trends. New York: Nova Science Publishers, 2010: 219-254.
[6]	La Hoz RM, Morris MI. Tissue and blood protozoa including toxoplasmosis, chagas disease, leishmaniasis, babesia, acanthamoeba, balamuthia, and naegleria in organ transplant recipients: guidelines from the American Society of Transplantation Infectious Diseases Community of Practice[J]. Clin Transplant, 2019,33(9):e13546.
[7]	Campbell AL, Goldberg CL, Magid MS, et al. First case of toxoplasmosis following small bowel transplantation and systematic review of tissue-invasive toxoplasmosis following noncardiac solid organ transplantation[J]. Transplantation, 2006,81(3):408-417.
[8]	Hommann M, Schotte U, Voigt R, et al. Cerebral toxoplasmosis after combined liver-pancreas-kidney and liver-pancreas transplantation[J]. Transplant Proc, 2002,34(6):2294-2295.
[9]	Nasser QJ, Power RE, Eng MP, et al. Toxoplasmosis after a simultaneous pancreas and kidney transplantation[J]. Transplant Proc, 2004,36(9):2843-2844.
[10]	Seguro FS, Assis RA, Silveira PAA, et al. Toxoplasma gondii in the bone marrow after pancreas-kidney transplantation[J]. Br J Haematol, 2009,147(3):276.
[11]	Munir A, Zaman M, Eltorky M. Toxoplasma gondii pneumonia in a pancreas transplant patient[J]. South Med J, 2000,93(6):614-617.
[12]	Fernàndez-Sabé N, Cervera C, Fariñas MC, et al. Risk factors, clinical features, and outcomes of toxoplasmosis in solid-organ transplant recipients: a matched case-control study[J]. Clin Infect Dis, 2012,54(3):355-361.
[13]	Muñoz P, Arencibia J, Rodríguez C, et al. Trimethoprim-sulfamethoxazole as toxoplasmosis prophylaxis for heart transplant recipients[J]. Clin Infect Dis, 2003,36(7):932-934.
[14]	Montoya JG, Giraldo LF, Efron B, et al. Infectious complications among 620 consecutive heart transplant patients at stanford university medical center[J]. Clin Infect Dis, 2001,33(5):629-640.
[15]	McGregor CG, Fleck DG, Nagington J, et al. Disseminated toxoplasmosis in cardiac transplantation[J]. J Clin Pathol, 1984,37(1):74-77.
[16]	Mastrobuoni S, Dell’aquila AM, Herreros J. Fatal Toxoplasma gondii dissemination in a heart transplant recipient: description of a case[J]. Case Rep Transplant, 2012,2012:524279.
[17]	Castagnini M, Bernazzali S, Ginanneschi C, et al. Fatal disseminated toxoplasmosis in a cardiac transplantation with seropositive match for Toxoplasma: should prophylaxis be extended?[J]. Transpl Immunol, 2007,18(2):193-197.
[18]	Anthony CW. Disseminated toxoplasmosis in a liver transplant patient[J]. J Am Med Women’s Assoc 1972, 1972,27(11):601-603.
[19]	Barcán LA, Dallurzo ML, Clara LO, et al. Toxoplasma gondii pneumonia in liver transplantation: survival after a severe case of reactivation[J]. Transpl Infect Dis, 2002,4(2):93-96.
[20]	Fabiani S, Fortunato S, Bruschi F. Solid organ transplant and parasitic diseases: a review of the clinical cases in the last two decades[J]. Pathogens, 2018,7(3):65.
[21]	Autier B, Dion S, Robert-Gangneux F. The liver as an organ at risk for Toxoplasma transmission during transplantation: myth or reality?[J]. J Clin Pathol, 2018,71(9):763-766.
[22]	de la Luz Galván-Ramírez M, Sánchez-Orozco LV, Gutiérrez-Maldonado AF, et al. Does Toxoplasma gondii infection impact liver transplantation outcomes? A systematic review[J]. J Med Microbiol, 2018,67(4):499-506.
[23]	Sun Y, Yu LX. A case of Toxoplasma gondii encephalitis after orthotopic liver transplantation[J]. Chin J Organ Transpl, 2018,39(8):499-501. (in Chinese)
[23]	( 孙雁, 于立新. 原位肝移植术后弓形虫脑炎一例[J]. 中华器官移植杂志, 2018,39(8):499-501.)
[24]	Gay J, Gendron N, Verney C, et al. Disseminated toxoplasmosis associated with hemophagocytic syndrome after kidney transplantation: a case report and review[J]. Transpl Infect Dis, 2019,21(5):e13154.
[25]	Rogers NM, Peh CA, Faull R, et al. Transmission of toxoplasmosis in two renal allograft recipients receiving an organ from the same donor[J]. Transpl Infect Dis, 2008,10(1):71-74.
[26]	Segall L, Moal MC, Doucet L, et al. Toxoplasmosis-associated hemophagocytic syndrome in renal transplantation[J]. Transpl Int, 2006,19(1):78-80.
[27]	Martina MN, Cervera C, Esforzado N, et al. Toxoplasma gondii primary infection in renal transplant recipients. Two case reports and literature review[J]. Transpl Int, 2011,24(1):e6-e12.
[28]	Hébraud B, Kamar N, Borde JS, et al. Unusual presentation of primary toxoplasmosis infection in a kidney-transplant patient complicated by an acute left-ventricular failure[J]. NDT Plus, 2008,1(6):429-432.
[29]	Botterel F, Ichai P, Feray C, et al. Disseminated toxoplasmosis, resulting from infection of allograft, after orthotopic liver transplantation: usefulness of quantitative PCR[J]. J Clin Microbiol, 2002,40(5):1648-1650.
[30]	Patrat-Delon S, Gangneux JP, Lavoué S, et al. Correlation of parasite load determined by quantitative PCR to clinical outcome in a heart transplant patient with disseminated toxoplasmosis[J]. J Clin Microbiol, 2010,48(7):2541-2545.
[31]	Colombo FA, Vidal JE, Penalva de Oliveira AC, et al. Diagnosis of cerebral toxoplasmosis in AIDS patients in Brazil: importance of molecular and immunological methods using peripheral blood samples[J]. J Clin Microbiol, 2005,43(10):5044-5047.
[32]	Fricker-Hidalgo H, Brion JP, Durand M, et al. Disseminated toxoplasmosis with pulmonary involvement after heart transplantation[J]. Transpl Infect Dis, 2005,7(1):38-40.
[33]	Mechain B, Garin YJ, Robert-Gangneux F, et al. Lack of utility of specific immunoglobulin G antibody avidity for serodiagnosis of reactivated toxoplasmosis in immunocompromised patients[J]. Clin Diagn Lab Immunol, 2000,7(4):703-705.
[34]	Held TK, Krüger D, Switala AR, et al. Diagnosis of toxoplasmosis in bone marrow transplant recipients: comparison of PCR-based results and immunohistochemistry[J]. Bone Marrow Transp, 2000,25(12):1257-1262.
[35]	Dard C, Marty P, Brenier-Pinchart MP, et al. Management of toxoplasmosis in transplant recipients: an update[J]. Expert Rev Anti Infect Ther, 2018,16(6):447-460.
[36]	Robert-Gangneux F, Meroni V, Dupont D, et al. Toxoplasmosis in transplant recipients, Europe, 2010—2014[J]. Emerg Infect Dis, 2018,24(8):1497-1504.
[37]	Petty LA, Qamar S, Ananthanarayanan V, et al. Cardiac toxoplasmosis after heart transplantation diagnosed by endomyocardial biopsy[J]. Transpl Infect Dis, 2015,17(5):719-722.
[38]	Ramanan P, Scherger S, Benamu E, et al. Toxoplasmosis in non-cardiac solid organ transplant recipients: a case series and review of literature[J]. Transpl Infect Dis, 2020,22(1):e13218.
[39]	Baden LR, Katz JT, Franck L, et al. Successful toxoplasmosis prophylaxis after orthotopic cardiac transplantation with trimethoprim-sulfamethoxazole[J]. Transplantation, 2003,75(3):339-343.
[40]	Strabelli TM, Siciliano RF, Vidal Campos S, et al. Toxoplasma gondii myocarditis after adult heart transplantation: successful prophylaxis with pyrimethamine[J]. J Trop Med, 2012,2012:853562.
[41]	Webb GJ, Shah H, David MD, et al. Post-prophylaxis Toxoplasma chorioretinitis following donor-recipient mismatched liver transplantation[J]. Transpl Infect Dis, 2016,18(5):805-808.
[42]	Conrad A, Le Maréchal M, Dupont D, et al. A matched case-control study of toxoplasmosis after allogeneic haematopoietic stem cell transplantation: still a devastating complication[J]. Clin Microbiol Infect, 2016,22(7):636-641.
[43]	Kortagere S. Novel molecules to treat chronic central nervous system toxoplasmosis[J]. J Med Chem, 2017,60(24):9974-9975.
[44]	Wreghitt TG, Hakim M, Gray JJ, et al. Toxoplasmosis in heart and heart and lung transplant recipients[J]. J Clin Pathol, 1989,42(2):194-199.
[45]	Hermanns B, Brunn A, Schwarz ER, et al. Fulminant toxoplasmosis in a heart transplant recipient[J]. Pathol Res Pract, 2001,197(3):211-215.
[46]	Baliu C, Sanclemente G, Cardona M, et al. Toxoplasmic encephalitis associated with meningitis in a heart transplant recipient[J]. Transpl Infect Dis, 2014,16(4):631-633.
[47]	Michaels MG, Wald ER, Fricker FJ, et al. Toxoplasmosis in pediatric recipients of heart transplants[J]. Clin Infect Dis, 1992,14(4):847-851.
[48]	Dávila V, Roncancio-Villamil G, Correa LA, et al. Disseminated toxoplasmosis in a heart transplant patient despite co-trimoxazole prophylaxis: a case report[J]. Biomedica, 2017,37(3):303-307.
[49]	Wreghitt TG, Gray JJ, Pavel P, et al. Efficacy of pyrimethamine for the prevention of donor-acquired Toxoplasma gondii infection in heart and heart-lung transplant patients[J]. Transpl Int, 1992,5(4):197-200.
[50]	Wendum D, Carbonell N, Svrcek M, et al. Fatal disseminated toxoplasmosis in a Toxoplasma seropositive liver transplant recipient[J]. J Clin Pathol, 2002,55(8):637.
[51]	Chiquet C, Fleury J, Blanc-Jouvan M, et al. Toxoplasmose oculaire acquise (panuvéite) après transplantation hépatique [Acquired ocular toxoplasmosis (panuveitis) after liver transplantation[J]. J Fr Ophtalmol, 2000,23(4):375-379.
[52]	Galván Ramírez ML, Castillo-de-León Y, Espinoza-Oliva M, et al. Acute infection ofToxoplasma gondii and cytomegalovirus reactivation in a pediatric patient receiving liver transplant[J]. Transpl Infect Dis, 2006,8(4):233-236.
[53]	Assi MA, Rosenblatt JE, Marshall WF. Donor-transmitted toxoplasmosis in liver transplant recipients: a case report and literature review[J]. Transpl Infect Dis, 2007,9(2):132-136.
[54]	Vaessen N, Verweij JJ, Spijkerman IJB, et al. Fatal disseminated toxoplasmosis after liver transplantation: improved and early diagnosis by PCR[J]. Neth J Med, 2007,65(6):222-223.
[55]	Caner A, Dökaya M, Karasu Z, et al. Incidence and diagnosis of active Toxoplasma infection among liver transplant recipients in Western Turkey[J]. Liver Transpl, 2008,14(10):1526-1532.
[56]	Miltgen G, Paillot J, Vanlemmens C, et al. Fatal acute respiratory distress by Toxoplasma gondii in a Toxoplasma seronegative liver transplant recipient[J]. New Microbiol, 2016,39(2):160-162.
[57]	Singh N, Gayowski T, Marino IR. Toxoplasma gondii pneumonitis in a liver transplant recipient: implications for diagnosis[J]. Liver Transpl, 1996,2(4):299-300.
[58]	Uçkay I, Wunderli W, Giostra E, et al. False serologic evidence for acute primary toxoplasmosis during liver transplantation for fulminant hepatitis B: a case report[J]. Transplant Proc, 2009,41(10):4425-4427.
[59]	Karras A, Thervet E, Legendre C, et al. Hemophagocytic syndrome in renal transplant recipients: report of 17 cases and review of literature[J]. Transplantation, 2004,77(2):238-243.
[60]	Giordano LFC, Lasmar EP, Tavora ERF, et al. Toxoplasmosis transmitted via kidney allograft: case report and review[J]. Transplant Proc, 2002,34(2):498-499.
[61]	Manz T, Grotz W, Orszagh M, et al. A patient with neurological deficits and seizures after renal transplantation[J]. Nephrol Dial Transplant, 2001,16(3):631-633.
[62]	Renoult E, Georges E, Biava MF, et al. Toxoplasmosis in kidney transplant recipients: report of six cases and review[J]. Clin Infect Dis, 1997,24(4):625-634.
[63]	Schmidt B, Wieneke H, Fahrenkamp A, et al. Encephalitic and myocardial toxoplasmosis masquerading as cytomegalovirus infection in a renal allograft recipient[J]. Nephrol Dial Transplant, 1995,10(2):284-286.
[64]	Mejia G, Leiderman E, Builes M, et al. Transmission of toxoplasmosis by renal transplant[J]. Am J Kidney Dis, 1983,2(6):615-617.
[65]	Wulf MW, van Crevel R, Portier R, et al. Toxoplasmosis after renal transplantation: implications of a missed diagnosis[J]. J Clin Microbiol, 2005,43(7):3544-3547.
[66]	Clissold R, Bingham C. Late presentation of toxoplasmosis in renal transplant recipients[J]. NDT Plus, 2010,3(5):480-482.
[67]	Vaughan LB, Wenzel RP. Disseminated toxoplasmosis presenting as septic shock five weeks after renal transplantation[J]. Transpl Infect Dis, 2013,15(1):E20-E24.
[68]	Shamim S, Mukherjee A, Bal C, et al. Cerebral toxoplasmosis masquerading CNS lymphoma on FDG PET-CT in post renal transplant patient[J]. Indian J Nucl Med, 2017,32(2):148.
[69]	Bagchi S, Sachdev SS, Nalwa A, et al. Multiple intracranial space-occupying lesions in a renal transplant recipient from an area endemic for tuberculosis (TB): TB vs. toxoplasmosis[J]. Transpl Infect Dis, 2014,16(5):838-842.
[70]	Lanfranco L, Olle Delahaye P, Dorr G, et al. Late isolated ocular toxoplasmosis in a belatacept-treated kidney transplant patient[J]. Transpl Int, 2016,29(12):1352-1353.
[71]	Da Cunha S, Ferreira E, Ramos I, et al. Cerebral toxoplasmosis after renal transplantation. Case report and review[J]. Acta Med Port, 1994,7(Suppl 1):S61-S66.

实体器官移植与弓形虫病

Solid organ transplantation and toxoplasmosis

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