中国寄生虫学与寄生虫病杂志 ›› 2001, Vol. 19 ›› Issue (4): 12-238.

• 临床研究 • 上一篇    下一篇

艾滋病合并肝脏肺孢子虫病一例病理观察

管小琴1;周立春2;廖小岗1;林晓1;李圆圆 1
  

  1. 重庆医科大学病理教研室!重庆400016(管小琴;廖小岗;林晓;李圆圆);重庆市传染病医院!重庆400030(周立春)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2001-08-30 发布日期:2001-08-30

Pathological Changes of Diffuse Pneumocystis carinii Infection in the Liver of an AIDS Patient

GUAN Xiao-qin1;ZHOU Li-chun2;LIAO Xiao-gang1;LIN Xiao1;LI Yuan-yuan1   

  1. 1\ Department of Pathology;Chongqing Medical University;Chongqing 400016; 2\ Chongqing Infectious Diseases Hospital;Chongqing 400030
  • Received:1900-01-01 Revised:1900-01-01 Online:2001-08-30 Published:2001-08-30

摘要:

  目的 观察艾滋病合并播散性肺孢子虫病的肝脏改变。 方法 用 HE、PAS、吉氏、六胺银和抗酸染色观察 1例艾滋病患者肝穿刺组织病理改变。 结果 肝组织有肉芽肿形成 (抗酸阴性 ) ,血窦中见大量病原体(PAS阳性 )。吉氏、六胺银染色和电镜所见证实为肺孢子虫 (PC)感染。 结论 本例肝脏病变是肺外肺孢子虫病引起 ,为全身性播散的表现。

关键词: 艾滋病, 肺孢子虫, 肝脏, 病理学

Abstract:  Objective To examine the pathological changes in the liver of an AIDS patient with complicated infection of Pneumocystis carinii(PC). \ Methods\ A liver biopsy was made. The tissue was stained with HE, PAS, Giemsa, GMS, and acid-fast staining, and examined under light microscope and transmission electron microscope. \ Results\ Granulomas (acid-fast negative) in the tissue and numerous pathogens (PAS positive) in hepatic sinusoids were detected. Giemsa and GMS staining and electron microscopy all confirmed that the pathogen was Pneumocystis carinii. \ Conclusion\ The pathological findings revealed a diffuse extrapulmonary infection of Pneumocystis carinii in the patient of AIDS.

Key words: AIDS, Pneumocystis carinii (PC), liver, pathology