华支睾吸虫病发病机制及防控研究进展

doi:10.12140/j.issn.1000-7423.2025.04.018

中国寄生虫学与寄生虫病杂志 ›› 2025, Vol. 43 ›› Issue (4): 567-574.doi: 10.12140/j.issn.1000-7423.2025.04.018

华支睾吸虫病发病机制及防控研究进展

李盼鸽(), 付京花, 徐民俊^*()

华南农业大学海洋学院，华南农业大学省级现代农业（水产品质量安全）产业技术研发中心，广东广州 510642

收稿日期:2024-12-11 修回日期:2025-04-20 出版日期:2025-08-30 发布日期:2025-10-09
通讯作者: *徐民俊，男，博士，研究员，从事华支睾吸虫病研究。E-mail: xuminjun@scau.edu.cn
作者简介:李盼鸽，女，硕士研究生，从事华支睾吸虫病研究。E-mail：pange_li@163.com
基金资助:
广东省科技专项资金“大专项+任务清单”竞争择优类项目(220720171471924)

Research progress on the pathogenesis and control of clonorchiasis

LI Pange(), FU Jinghua, XU Minjun^*()

College of Marine Sciences, South China Agricultural University, Provincial Modern Agriculture (Aquatic Product Quality and Safety) Industrial Technology R&D Center of South China Agricultural University, Guangzhou 510642, Guangdong, China

Received:2024-12-11 Revised:2025-04-20 Online:2025-08-30 Published:2025-10-09
Contact: *E-mail: xuminjun@scau.edu.cn
Supported by:
Competitive Selection Program for “Major Special Projects + Task List”(220720171471924)

摘要/Abstract

摘要：

华支睾吸虫以鱼虾等为中间宿主，以哺乳动物为终末宿主，是一种重要的人兽共患寄生虫。该病原体主要导致胆管癌变等消化系统疾病。随着我国居民消费水平的提升和消费结构的变化，国内因食生或半生鱼类引起的华支睾吸虫病感染人数高达1 300多万，成为食品安全和公共卫生领域中亟待解决的问题。本文对近年来国内外学者在华支睾吸虫感染发病机制及防控措施的最新研究进行综述，以期为该病原体的监测、预防和控制策略提供参考。

关键词: 华支睾吸虫, 发病机制, 鱼类, 防控

Abstract:

Clonorchis sinensis is an important zoonotic parasite with fish and shrimp as intermediate hosts and mammals as definitive hosts, which mainly causes digestive diseases, such as cholangiocarcinoma. With improvements of residents’ consumption level and changes of consumption structure in China, the number of human clonorchiasis cases caused by consuming raw or half cooked fish reaches up to more than 13 million in China, and clonorchiasis has become an urgent problem to be solved in the field of food safety and public health. This article reviews the latest international and national advances in the pathogenesis and prevention and control measures of C. sinensis infection in recent years, so as to provide insights into surveillance, prevention and control of this pathogen.

Key words: Clonorchis sinensis, Pathogenesis, Fish, Prevention and control

中图分类号:

R532.23

李盼鸽, 付京花, 徐民俊. 华支睾吸虫病发病机制及防控研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2025, 43(4): 567-574.

LI Pange, FU Jinghua, XU Minjun. Research progress on the pathogenesis and control of clonorchiasis[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2025, 43(4): 567-574.

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华支睾吸虫病发病机制及防控研究进展

Research progress on the pathogenesis and control of clonorchiasis

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