福建省人感染异尖线虫1例

doi:10.12140/j.issn.1000-7423.2022.04.023

中国寄生虫学与寄生虫病杂志 ›› 2022, Vol. 40 ›› Issue (4): 556-558.doi: 10.12140/j.issn.1000-7423.2022.04.023

福建省人感染异尖线虫1例

黄姝玲¹(), 林诗涵¹, 邱希斌¹, 陈永煊¹, 林陈鑫²^,^*()

1.福建省产品质量检验研究院,350002 福州
2.福建省疾病预防控制中心,350001 福州

收稿日期:2022-01-28 修回日期:2022-03-08 出版日期:2022-08-30 发布日期:2022-09-07
通讯作者: 林陈鑫
作者简介:黄姝玲（1989-）女,硕士研究生,从事寄生虫学、微生物学和分子生物学检验研究。E-mail： 175680220@qq.com
基金资助:
国家市场监督管理总局科技计划项目(2019MK037)

A case of Anisakis infection in Fujian Province

HUANG Shu-ling¹(), LIN Shi-han¹, QIU Xi-bin¹, CEHN Yong-xuan¹, LIN Chen-xin²^,^*()

1. Fujian Inspection and Research Institute for Product Quality, Fuzhou 350002, China
2. Fujian Center for Disease Control and Prevention, Fuzhou 350001, China

Received:2022-01-28 Revised:2022-03-08 Online:2022-08-30 Published:2022-09-07
Contact: LIN Chen-xin
Supported by:
Science and Technology Project of State Administration for Market Regulation(2019MK037)

摘要/Abstract

摘要：

患者,男,46岁,于2021年12月在体检中行肠镜检查时,发现其回盲部寄生一条似寄生虫,可蠕动,予活检钳取出。肠镜下,虫体寄生部位的肠黏膜未见异常,肠腔内未见异常。取出的虫体经形态学鉴定,初步确定为简单异尖线虫;提取虫体DNA,进行PCR检测,所得扩增片段约为1 000 bp,测序后经BLAST比对分析,与简单异尖线虫的序列一致性达99%;经系统进化树分析,与简单异尖线虫聚为一簇。确认该患者回盲部寄生的虫体为简单异尖线虫。患者自述,长期居住于东南沿海城市,有多年食生海鲜制品史。取出虫体后未诉有不适感,故未行其他检查和治疗。

关键词: 异尖线虫, 形态学, 分子生物学, 福建省

Abstract:

An 42-year-old male patient who was found to have a parasite in his ileocecal region during a colonoscopy examination in December 2021. The worm was reported motile and was removed with biopsy forceps. During the colonoscopy, no abnormality was found in the intestinal mucosa where the parasite was found and no abnormality was found in the intestinal lumen. The extracted parasite was identified as Anisakis simplex preliminarily by morphological identification. DNA was extracted from parasites and tested by PCR. The amplified fragment was about 1 000 bp. After sequencing, BLAST analysis showed that it was consistent with Anisakis simplex up to 99%. By phylogenetic tree analysis, it was clustered with Anisakis simplex. The parasite was confirmed to be Anisakis simplex. The patient reported that he had lived in southeast coastal cities for a long time and had a history of eating raw seafood products for many years. No discomfort was reported after the parsite was removed, so no other examination and treatments were performed.

Key words: Anisakiasis, Morphology, Analysis and Identification, Fujian Province

中图分类号:

R383.1

黄姝玲, 林诗涵, 邱希斌, 陈永煊, 林陈鑫. 福建省人感染异尖线虫1例[J]. 中国寄生虫学与寄生虫病杂志, 2022, 40(4): 556-558.

HUANG Shu-ling, LIN Shi-han, QIU Xi-bin, CEHN Yong-xuan, LIN Chen-xin. A case of Anisakis infection in Fujian Province[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2022, 40(4): 556-558.

图/表 4

参考文献 15

[1]	Zhang JS. Clinical parasitosis laboratory[M]. Beijing: People’s Medical Publishing, 2009: 562-570. (in Chinese)
	( 张进顺. 临床寄生虫检验学[M]. 北京: 人民卫生出版社, 2009: 562-570.)
[2]	Zhu X, et al. Characterisation of anisakid nematodes with zoonotic potential by nuclear ribosomal DNA sequences[J]. Int J Parasitol, 1998, 28(12) : 1911-21.
[3]	Adamson Martin L, Anderson Roy C. Nematode parasites of vertebrates. Their development and transmission[J]. J Parasitol, 1993, 79(4): 634.
[4]	Rahmati AR, KianiI B, Afshari A, et al. World-wide prevalence of Anisakis larvae in fish and its relationship to human allergic anisakiasis: a systematic review[J]. Parasitol Res, 2021, 120(5): 1-2.
[5]	Lin CX, Huang SL, Lin SH, et al. Infection and species identification of Anisakis larvae in sea fishes along Fujian coast[J]. Chin J Parasitol Parasit Dis, 2019, 37(4): 417-421. (in Chinese)
	( 林陈鑫, 黄姝玲, 林诗涵, 等. 福建省沿海鱼类异尖线虫幼虫感染情况调查及虫种鉴定[J]. 中国寄生虫学与寄生虫病杂志, 2019, 37(4): 417-421.)
[6]	Wei ZC, Zhang W, Deng XL. Investigation of Anisakis larvae infection in marine fish in markets of Anshan City, Liaoning Province[J]. Chin J Parasitol Parasit Dis, 2020, 38(6): 789-791. (in Chinese)
	( 魏卓超, 张巍, 邓晓丽. 辽宁省鞍山市市售海鱼异尖线虫幼虫感染情况调查[J]. 中国寄生虫学与寄生虫病杂志, 2020, 38(6): 789-791.)
[7]	Wang ZY, Wu HY, Jiang L, et al. Surveillance and analysis of parasitic infection in food on market in Shanghai during 2015—2019[J]. Chin J Parasitol Parasit Dis, 2021, 39(3): 347-351. (in Chinese)
	( 王真瑜, 吴寰宇, 江莉, 等. 2015—2019 年上海市市售食品寄生虫感染监测分析[J]. 中国寄生虫学与寄生虫病杂志, 2021, 39(3): 347-351.)
[8]	Qin YH, Zhao YF, Ren YX, et al. Anisakiasis in China: the first clinical case report[J]. Foodborne Pathog Dis, 2013, 10(5): 472-474.
[9]	Zhu HR, Liu L, Yang GJ. Prevalence situation of emerging parasitic zooneses in china[J]. Chin J Schisto Control, 2013, 25(4): 417-421. (in Chinese)
	( 朱宏儒, 刘璐, 杨国静. 我国新发人畜共患病寄生虫病的流行现状[J]. 中国血吸虫病防治杂志, 2013, 25(04): 417-421.)
[10]	Adroher-Auroux FJ, Benítez-Rodríguez R. Anisakiasis and Anisakis: an underdiagnosed emerging disease and its main etiological agents[J]. Res Vet Sci, 2020, 132: 535-545.
[11]	Yao YH. Diagnosis and prevention of anisakiasis[J]. Animal Sci Vet Med, 2002, 19(7): 41-42. (in Chinese)
	( 姚永华. 异尖线虫病的诊断与防治[J]. 动物科学与动物医学, 2002, 19(7): 41-42.)
[12]	Shimamura Y, Muwanwella N, Chandran S, et al. Commom symptoms from an uncommom infection: gastrointestinal anisakiasis[J]. Can J Gastroenterol, 2016( 2016): 1-7.
[13]	D’Amelio S, Mathiopoulos KD, Santos CP, et al. Genetic markers in ribosomal DNA for the identification of members of the genus Anisakis (Nematoda ∶ Ascaridoidea) defined by polymerase chain reaction-based restriction fragment length polymorphism[J]. Int J Parasitol, 2000, 30(2): 223-226.
[14]	Mattiucci S, Paggi L, Nascetti G, et al. Genetic divergence and reproductive isolation between Anisakis brevispiculata and Anisakis physeteris (Nematoda ∶ Anisakidae)[J]. Int Parasitol, 2001, 31(1): 9-14.
[15]	Martin-Sanchez J, Artacho-Reinoso ME, Disz-Gavilan M, et al. Structure of Anisakis simplex s.l. populations in a region sympatric for A. pegreffii and A. simplex s.s. absence of reproductive isolation between both species[J]. Mol Biochem Parasitol, 2005, 141(2): 155-162.

福建省人感染异尖线虫1例

A case of Anisakis infection in Fujian Province

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