[1] |
Jenkins DJ.WHO/OIE manual on echinococcosis, in humans and animals: a public health problem of global concern[J]. Int J Parasitol, 2001, 31(14): 1717-1718.
|
[2] |
Vuitton DA, Gottstein B.Echinococcus multilocularis and its intermediate host: a model of parasite-host interplay[J]. J Biomed Biotechnol, 2010, 2010: 1-14.
|
[3] |
Bataller R, Brenner DA.Liver fibrosis[J]. J Clin Invest, 2005, 115(2): 209-218.
|
[4] |
Ray K.Liver: hepatic stellate cells hold the key to liver fibrosis[J]. Nat Rev Gastroenterol Hepatol, 2014, 11(2): 74.
|
[5] |
Siracusano A, Delunardo F, Teggi A, et al. Host-parasite relationship in cystic echinococcosis: an evolving story[J]. Clin Dev Immunol, 2012, 2012: 639362.
|
[6] |
赵慧, 白雪, 聂晓涵, 等. 泡球蚴感染小鼠肝脏中IL-10和TGF-β的动态变化[J]. 中国寄生虫学与寄生虫病杂志, 2012, 30(1): 32-35.
|
[7] |
方海瑞, 蒋红群, 徐芳洁, 等. 原头蚴对体外培养小鼠脾细胞中Th细胞亚群的影响[J]. 中国免疫学杂志, 2016, 32(2): 174-177, 183.
|
[8] |
Brehm K.The role of evolutionarily conserved signalling systems in Echinococcus multilocularis development and host-parasite interaction[J]. Med Microbiol Immunol, 2010, 199(3): 247-259.
|
[9] |
倪兴维, 闫鸿斌, 娄忠子, 等. 多房棘球绦虫信号转导体系[J]. 中国寄生虫学与寄生虫病杂志, 2012, 30(3): 233-237.
|
[10] |
李瑶, 林仁勇, 徐琦, 等. 泡球蚴感染对BALB/c小鼠肝脏TGF-β1及其信号蛋白表达的影响[J]. 免疫学杂志, 2011, 27(3): 215-219.
|
[11] |
Huang G, Ye S, Zhou X, et al. Molecular basis of embryonic stem cell self-renewal: from signaling pathways to pluripotency network[J]. Cell Mol Life Sci, 2015, 72(9): 1741-1757.
|
[12] |
Ravenhall C, Guida E, Harris T, et al. The importance of ERK activity in the regulation of cyclin D1 levels and DNA synthesis in human cultured airway smooth muscle[J]. Br J Pharmacol, 2000, 131(1): 17-28.
|
[13] |
Shi Y, Massagué J.Mechanisms of TGF-beta signaling from cell membrane to the nucleus[J]. Cell, 2003, 113(6): 685-700.
|
[14] |
Fuchs O. Inhibition of TGF-β signaling for the treatment of tumor metastasis and fibrotic diseases[J]. Curr Signal Transduct Ther, 2011, 6(1): 29-43.
|
[15] |
Yoshimura A, Muto G.TGF-β function in immune suppression[J]. Curr Top Microbiol Immunol, 2011, 350: 127-147.
|
[16] |
Hill CS.Nucleocytoplasmic shuttling of Smad proteins[J]. Cell Res, 2009, 19(1): 36-46.
|
[17] |
Stenvers KL, Tursky ML, Harder KW, et al. Heart and liver defects and reduced transforming growth factor beta 2 sensitivity in transforming growth factor beta type Ⅲ receptor-deficient embryos[J]. Mol Cell Biol, 2003, 23(12): 4371-4385.
|
[18] |
张炳远, 张建余, 赵凯, 等. 胆管癌组织Smad4和转化生长因子β1级Ⅱ型受体的表达及意义[J]. 中华外科杂志, 2005, 43(13): 846-849.
|
[19] |
Saika S, Yamanaka O, Nishikawa-Ishida I, et al. Effect of Smad7 gene over expression on transforming growth factor beta-induced retinal pigment fibrosis in a proliferative vitreoretinopathy mouse model[J]. Arch Ophthalmol, 2007, 125(5): 647-654.
|
[20] |
Lucarelli P, Schilling M, Kreutz C, et al. Resolving the combinatorial complexity of Smad protein complex formation and its link to gene expression[J]. Cell Syst, 2018, 6(1): 75-89.
|
[21] |
Kleiter I, Song J, Lukas D, et al. Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis[J]. Brain, 2010, 133(Pt 4): 1067-1081.
|
[22] |
Xu F, Liu C, Zhou D, et al. TGF-β/SMAD pathway and its regulation in hepatic fibrosis[J]. J Histochem Cytochem, 2016, 64(3): 157-167.
|
[23] |
Wang J, Zhang C, Wei X, et al. TGF-β and TGF-β/Smad signaling in the interactions between Echinococcus multilocularis and its hosts[J]. PLoS One, 2013, 8(2): e55379.
|
[24] |
Zhu D, He X, Duan Y, et al. Expression of microRNA-454 in TGF-β1-stimulated hepatic stellate cells and in mouse livers infected with Schistosoma japonicum[J]. Parasit Vectors, 2014, 7: 148.
|
[25] |
Barros AF, Oliveira SA, Carvalho CL, et al. Low transformation growth factor-β1 production and collagen synthesis correlate with the lack of hepatic periportal fibrosis development in undernourished mice infected with Schistosoma mansoni[J]. Mem Inst Oswaldo Cruz, 2014, 109(2): 210-219.
|
[26] |
Attia YM, Elalkamy EF, Hammam OA, et al. Telmisartan, an AT1 receptor blocker and a PPAR gamma activator, alleviates liver fibrosis induced experimentally by Schistosoma mansoni infection[J]. Parasit Vectors, 2013, 6(1): 199.
|
[27] |
Wang J, Zhang C, Wei X, et al. TGF-β and TGF-β/Smad signaling in the interactions between Echinococcus multilocularis and its hosts[J]. PLoS One, 2013, 8(2): e55379.
|
[28] |
Yan C, Wang L, Li B, et al. The expression dynamics of transforming growth factor-β/Smad signaling in the liver fibrosis experimentally caused by Clonorchis sinensis[J]. Parasit Vectors, 2015, 8: 70.
|
[29] |
Pang N, Zhang F, Ma X, et al. TGF-β/Smad signaling pathway regulates Th17/Treg balance during Echinococcus multilocularis infection[J]. Int Immunopharmacol, 2014, 20(1): 248-257.
|
[30] |
周洋, 金一帮, 王俊华, 等. 细粒棘球蚴囊液对体外培养小鼠脾细胞Foxp3和Smad4基因表达的影响[J]. 中国病原生物学杂志, 2011, 6(3): 193-197.
|
[31] |
Yin S, Chen X, Zhang J, et al. The effect of Echinococcus granulosus on spleen cells and TGF-β expression in the peripheral blood of BALB/c mice[J]. Parasite Immunol, 2017, 39(3): e12415.
|
[32] |
张静, 曾静, 李亮, 等. Smad蛋白抑制剂SIS3对细粒棘球蚴原头节的作用研究[J]. 中国病原生物学杂志, 2017, 12(5): 389-393.
|
[33] |
Hong SK, Wu PK, Park JI.A cellular threshold for active ERK1/2 levels determines Raf/MEK/ERK-mediated growth arrest versus death responses[J]. Cell Signal, 2018, 42: 11-20.
|
[34] |
Androutsopoulos VP, Spandidos DA.Anticancer pyridines induce G2/M arrest and apoptosis via p53 and JNK upregulation in liver and breast cancer cells[J]. Oncol Rep, 2018, 39(2): 519-524.
|
[35] |
Cicenas J, Zalyte E, Rimkus A, ,et al. JNK.JNK, p38,ERK,SGK1 inhibitors in cancer[J]. Cancers (Basel), 2018, 10(1): pii: E1.
|
[36] |
王成华, 吕海龙, 姜玉峰, 等. 棘球蚴MAPK信号转导通路的研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2013, 31(1): 60-63.
|
[37] |
Kimata M, Michigami T, Tachikawa K, et al. Signaling of extracellular inorganic phosphate up-regulates cyclin D1 expression in proliferating chondrocytes via the Na+/Pi cotransporter Pit-1 and Raf/MEK/ERK pathway[J]. Bone, 2010, 47(5): 938-947.
|
[38] |
Kawanaka H, Tomikawa M, Baatar D, et al. Despite activation of EGF-receptor-ERK signaling pathway, epithelial proliferation is impaired in portal hypertensive gastric mucosa[J]. Life Sci, 2001, 69(25/26): 3019-3033.
|
[39] |
Patel A, Chojnowski AN, Gaskill K, et al. The role of a Brugia malayi p38 MAP kinase ortholog (Bm-MPK1) in parasite anti-oxidative stress responses[J]. Mol Biochem Parasitol, 2011, 176(2): 90-97.
|
[40] |
Cheng Z, Liu F, Li X, et al. EGF-mediated EGFR/ERK signaling pathway promotes germinative cell proliferation in Echinococcus multilocularis that contributes to larval growth and development[J]. PLoS Negl Trop Dis, 2017, 11(2): e0005418.
|
[41] |
Zhang C, Wang J, Lü G, et al. Hepatocyte proliferation/growth arrest balance in the liver of mice during E. ultilocularis infection: a coordinated 3-stage course[J]. PLoS One, 2012, 7(1): e30127.
|
[42] |
Gelmedin V, Caballero-Gamiz R, Brehm K.Characterization and inhibition of a p38-like mitogen-activated protein kinase (MAPK) from Echinococcus multilocularis: antiparasitic activities of p38 MAPK inhibitors[J]. Biochem Pharmacol, 2008, 76(9): 1068-1081.
|
[43] |
Gelmedin V, Spiliotis M, Brehm K.Molecular characterisation of MEK1/2- and MKK3/6-like mitogen-activated protein kinase kinases (MAPKK) from the fox tapeworm Echinococcus multilocularis[J]. Int J Parasitol, 2010, 40(5): 555-567.
|