关键词: 华支睾吸虫病, 江门市, 横断面研究, 流行病学

Abstract:

Objective  To investigate the prevalence of clonorchiasis in Jiangmen City.  Methods  From May to December 2011， each town was randomly chosen from east， south， west， north and central area of 7 cities/districts of Jiangmen City. Four or five villages were randomly selected from each town. In each village， the residents above 3-year-old in 10% randomly sampled families were treated as research objects. Total of 14 000 fecal boxes were issued and 12 661 ones back. Eggs in stool were examined by modified Kato-Katz thick smear method（three slides per specimen）.  Results  A total of 1 316 clonorchiasis cases were found from 12 661 pepople in 140 villages with a prevalence of 10.39% （1 316/12 661）. The average egg density was 98.3 eggs per gram（EPG） feces. Among 7 cities/districts， the prevalence in Pengjiang District（26.68%， 402/1 507） was the highest， and that of Taishan City（0.93%， 19/2 049） was the lowest. The egg density in Heshan City was the highest （225.4 EPG） and the lowest one was found in Taishan City （5.13 EPG）. The prevalence was negatively related with the distance to major rivers（r=-0.61，P<0.01）. The prevalence and the egg density in males and females was 13.20% （807/6 112） and 80.9 EPG， and 7.77% （509/6 549） and 39.4 EPG， respectively. The prevalence and intensity of infection increased obviously in the groups of above 20-year-old. The people with a higher prevalence was the group of 60-69 year-old， and the people above 70 years showed heavier infection（153.8 EPG）. Light， moderate and heavy infection occupied 99.91%， 0.09%， and 0.  Conclusion  Clonorchiasis is endemic in seven districts of Jiangmen City with different epidemic degrees. There are significant differences in the prevalence and intensity of infection among different areas. The villages with higher prevalence distribute along the middle and lower sections of the two major rivers.

Key words: Clonorchiasis sinensis, Jiangmen City, Cross-sectional study, Epidemiology