中国寄生虫学与寄生虫病杂志

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顶复门线粒体基因组结构的研究进展

黎雪梅1,李小兵2,3,黄伟1 *   

  1. 1 西南大学荣昌校区动物医学系,重庆 402460;2 中国科学院水生生物研究所,水生生物多样性与保护重点实验室,武汉 430072;3 中国科学院大学,北京 100049
  • 出版日期:2014-10-30 发布日期:2015-01-06

Research Progress on Mitochondrial Genome Structure in the Phylum Apicomplexa

LI Xue-mei1,LI Xiao-bing2,3,HUANG Wei1 *   

  1. 1  Department of Veterinary Medicine,Rongchang Campus,Southwest University,Chongqing 402460,China;2 Key Laboratory of Aquatic Biodiversity and Conservation,Institute of Hydrobiology,Chinese Academy of Sciences,Wuhan 430072,China;3 University of Chinese Academy of Sciences,Beijing 100049,China
  • Online:2014-10-30 Published:2015-01-06

摘要:

线粒体是一种在所有真核细胞中普遍存在的细胞器,它对一系列的细胞代谢及信号传递过程中起着重要作用。顶复门(Apicomplexa)包含了许多单细胞真核生物,其中部分寄生虫具有非常重要的临床和经济学意义。最近的研究表明,顶复门寄生虫线粒体基因组结构存在多样性,故可作为理解线粒体基因组演化的重要生物模型之一。本文综述了部分具有代表性的顶复门寄生虫的线粒体基因组结构,强调了它们线粒体基因组的结构特点及其演变过程,并概述了其核线粒体DNA和顶质体DNA。

关键词: 顶复门, 寄生虫, 线粒体基因

Abstract:

Mitochondria are ubiquitous organelles in all eukaryotic cells which are essential for a series of cellular processes and signal transduction. The phylum Apicomplexa includes series of unicellular eukaryotes and some of them are clinically or economically important parasites. Recent studies have demonstrated that apicomplexan parasites′ mitochondrial genomes exhibit remarkably diverse structures and they are ideal biological models to comprehend the evolution of mitochondrial genomes. This paper summarizes the mitochondrial genome structure of some representative apicomplexan, highlights their structure characteristics along with evolution process, and briefly describes their nuclear mitochondrial DNA and nuclear plastid DNA.

Key words: Apicomplexa, Parasite, Mitochondrial genome