中国寄生虫学与寄生虫病杂志 ›› 2012, Vol. 30 ›› Issue (2): 9-127-130.

• 现场研究 • 上一篇    下一篇

青海省儿童棘球蚴病的地域分布

 蔡辉霞1, 官亚宜1*, 王虎2, 伍卫平1, 韩秀敏2, 马霄2, 王立英1, 李俊1   

  1. 1 中国疾病预防控制中心寄生虫病预防控制所,卫生部寄生虫病原与媒介生物学重点实验室,世界卫生组织疟疾、血吸虫病和丝虫病合作中心,上海 200025;2 青海省地方病预防控制所,西宁 811602
  • 出版日期:2012-04-30 发布日期:2012-09-28

Geographical Distribution of Echinococcosis among Children in Qinghai Province

CA  Hui-Xia1, GUAN  Ya-Yi1*, WANG  Hu2, WU  Wei-Beng1, HAN  Xiu-Min2, MA  Xiao2, WANG  Li-Yang1, LI  Dun1   

  1. 1 National Institute of Parasitic Diseases,Chinese Center for Disease Control and Prevention; Key Laboratory of Parasite and Vector Biology,MOH;WHO Collaborating Center of Malaria,Schistosomiasis and Filariasis,Shanghai 200025,China;2 Qinghai Provincial Institute for Endemic Disease Control,Xining 811602,China
  • Online:2012-04-30 Published:2012-09-28

摘要: 目的  分析2000-2010年青海省辖区内不同地形区儿童棘球蚴病的流行状况,明确儿童棘球蚴病的地域分布。  方法  对青海省青南高原、祁连山地-河湟谷地和柴达木盆地等3类地形区的6~15岁儿童采用ELISA和B超进行棘球蚴病感染和患病情况的调查。  结果  共B超调查20 730名儿童,总患病率为1.5%(320/20 730),其中细粒棘球蚴病患病率为1.0%(206/20 730),多房棘球蚴病患病率为0.6%(114/20 730);ELISA检测血清总阳性率为6.5% (1 024/15 762)。青南高原、祁连山地-河湟谷地和柴达木盆地的血清阳性率和患病率分别为9.5%(707/7 453)和2.3%(269/11 618)、3.8%(289/7 544)和0.6%(50/8 275)、3.7%(28/765)和0.1%(1/837)。而青南高原儿童棘球蚴病的血清阳性率和患病率明显高于其他2个地形区,三者间的差异有统计学意义(P<0.01)。儿童多房棘球蚴病仅在青南高原发现,患病率为1.0%(114/11 618);直线回归分析表明,不同平均海拔与儿童棘球蚴病血清阳性率(r=0.96,P<0.05,R2=0.93)和患病率(r=0.82,P<0.05,R2=0.67)之间存在正相关关系。 结论  儿童棘球蚴病的流行在青海省具有明显地域分布特征。

关键词: 青海省, 儿童, 棘球蚴病, 地域分布

Abstract: Objective  To analyze the epidemiological status of echinococcosis among children in three different zones of Qinghai Province.  Methods   B-ultrasound and ELISA were used in the survey to evaluate echinococcus infection among 6~15 year old children in the three zones,namely,Qinghai southern plateau,Qilian mountain-Hehuang valley and Chaidamu basin.   Results  The prevalence of echinococcus infection scanned by B-ultrasound and sera positive rate detected by ELISA in children were 1.5%(320/20 730)and 6.5%(1024/15 762)respectively,and the prevalence of cystic echinococcosis and alveolar echinococcosis by ultrasound were 1.0%(206/20 730)and 0.6%(114/20 730),respectively. The prevalence and sera positive rate were 9.5%(707/7 453)and 2.3%(269/11 618) in Qinghai southern plateau, 3.8%(289/7 544) and 0.6%(50/8 275) in Qilian mountain-Hehuang valley, and 3.7%(28/765)and 0.1%(1/837) in Chaidamu basin, respectively. The southern plateau showed the highest prevalence, with a significant statistical difference among the three areas(P<0.01). The prevalence of alveolar echinococcosis was 1.0%(114/11 618)in the southern plateau, but no alveolar echinococcosis patients were found in other two areas. Correlation analysis showed that the prevalence increased with the altitude (r s-e=0.96,P<0.05,R 2=0.93;r p-e=0.82,P<0.05,R 2=0.67).  Conclusion  The prevalence of echinococcosis among children shows an apparent geographical difference in Qinghai Province.

Key words: Qinghai Province, Children, Echinococcosis, Geographical Distribution