中国寄生虫学与寄生虫病杂志 ›› 2008, Vol. 26 ›› Issue (2): 11-131.

• 现场研究 • 上一篇    下一篇

新发现的内脏利什曼病流行区新疆民丰县Ⅰ. 流行病学调查

伊斯拉音·乌斯曼1,金长发2,左新平1,顾灯安2,兰勤娴2,童苏祥1,李雄1,张仪2,茹孜古丽·朱马洪1,牛新玲1,阿不力米提3,木合塔4,阿布都外力4,库尔班4   

  1. 1 新疆维吾尔自治区疾病预防控制中心,乌鲁木齐 830002; 2 中国疾病预防控制中心寄生虫病预防控制所,世界卫生组织疟疾、血吸虫病和丝虫病合作中心,上海 200025; 3 新疆维吾尔自治区民丰县安迪尔乡卫生院,民丰 848500;4 新疆维吾尔自治区民丰县疾病预防控制中心,民丰848500
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2008-04-30 发布日期:2008-04-30

A Newly Identified Endemic Area of Visceral Leishmaniasis in Minfeng County of South Xinjiang Ⅰ. Epidemiological Survey

Yisilayin OSMAN1,JIN Chang-fa2,ZUO Xin-ping1,GU Deng-an2,LAN Qin-xian2,TONG Su-xiang1,LI Xiong1,ZHANG Yi2,Ruziguli JUMAHUN1,NIU Xin-ling1,Abulimiti3,Muhetaer4,Abuduwaili4,Kuerban4   

  1. 1 Center for Disease Control and Prevention of Xinjiang Uygur Autonomous Region,Urumqi 830002,China;2 National Institute of Parasitic Diseases,Chinese Center for Disease Control and Prevention,WHO Collaborating Centre for Malaria,Schistosomiasis and Filariasis,Shanghai 200025,China;3 Andier Township Hospital of Minfeng County,Minfeng 844000,China;4 Center for Diseases Control and Prevention of Minfeng County,Minfeng 844000,China
  • Received:1900-01-01 Revised:1900-01-01 Online:2008-04-30 Published:2008-04-30

摘要: 目的 对新疆民丰县一个新发现的内脏利什曼病(黑热病)流行区进行现场流行病学调查。 方法 2007年6月采用回顾性调查和现况调查相结合,对民丰县安迪尔乡所有居民进行逐户入户调查。内容包括家庭成员中20年来的健康状况、既往有无疑似内脏利什曼病史(包括已过世者),并对15岁以下儿童进行体查(触诊肝、脾);对部分居民进行利什曼素皮内试验和rk39免疫层析试条检测。 结果 共调查居民313人,未见现症病例。既往有疑似内脏利什曼病史者60例,其中13例已过世。171人进行利什曼素皮内试验检测,阳性率为99.4%(170/171),其中有疑似内脏利什曼病病史者的阳性率为96.6%(28/29)。197人进行rk39免疫层析试条检测,阳性率为10.2%(20/197),其中有疑似内脏利什曼病史者的阳性率为19.4%(6/31),追溯诊断为既往内脏利什曼病病例。 结论 新疆民丰县为内脏利什曼病流行区。

关键词: 内脏利什曼病(黑热病), 流行病学, rk39免疫层析试条, 利什曼素皮内试验, 新流行区, 新疆

Abstract: Objective To investigate the epidemiological status of visceral leishmaniasis in Minfeng county, a newly identified endemic area in south Xinjiang, China. Methods Based on a hint of possible existence of patients, a retrospective survey was carried out house by house in Andier Township of the county to find cases with suspected signs/symptoms of the disease in the past 20 years including those died. Meanwhile, a survey on current status was conducted, including physical examination(liver and spleen palpation) to those under 15 years-old,leishmanin skin test and rk39 immunochromatographic strip test for part of the residents. Results The investigation covered 313 local residents and revealed no case with present illness but 60 cases with a history of suspected signs/symptoms including 13 deaths, traced back as visceral leishmaniasis. Leishmanin skin test was performed in 171 people with a positive rate of 99.4% and 28 out of 29 suspected cases showed positive (96.6%). rk39 immunochromatographic strip test was conducted in 197 people with a positive rate of 10.2% (20/197) and 19.4% (6/31) in those with a history of suspected signs/symptoms. Conclusion The epidemiological investigation indicates that the Andier Township of Minfeng County is an endemic area of visceral leishmaniasis.

Key words: Visceral leishmaniasis(Kala-azar), Epidemiology, Immunochromatographic strip test, Leishmanin skin test, New endemic area, Xinjiang