关键词: 弓形虫病, 改良凝集试验, 胶乳凝集试验

Abstract: 　Objective] To evaluate the diagnostic value of three agglutination tests used in three countries for detection of antibodies to Toxoplasma gondii .[Methods] A total of 288 human serum samples were assayed using modified agglutination test (MAT 1,using selfmade antigen),latex agglutination test (LAT,using Japanese Kit) and modified agglutination test (MAT 2,using French antigen).[Results] The positive rates of MAT 1 (≥1∶20), LAT (≥1∶32) and MAT 2 (≥1∶20) were 9 7% (28/288), 8 9% (10/112) and 8 1% (17/210), respectively. No significant statistical difference was found among these positive rates (χ 2 =0 392, P >0 05). High agreements were found between MAT 1 and LAT (93 7%), LAT and MAT 2 (94 5%), and MAT 2 and MAT 1 (97 3%). Significant correlation were demonstrated in MAT 1 and LAT (r = 0 613), LAT and MAT 2 (r = 0 551), and MAT 2 and MAT 1 (r = 0 841), p <0 001.[Conclusion] The detection efficiency of the three agglutination tests is in good agreement and could alternatively be used for the diagnosis of toxoplasmosis.

Key words: Toxoplasmosis, modified agglutination test, latex agglutination test.