中国寄生虫学与寄生虫病杂志 ›› 1985, Vol. 3 ›› Issue (3): 187-188.

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应用间接荧光抗体试验进行疟疾纵向调查

郑一民,林文振,许龙善   

  1. 福建省浦城县卫生防疫站; 福建省浦城县卫生防疫站; 福建省寄生虫病研究所
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1985-08-31 发布日期:2017-01-12

INDIRECT FLUORESCENT ANTIBODY TEST IN A LONGITUDINAL SURVEY OF MALARIA

  • Received:2017-01-12 Revised:2017-01-12 Online:1985-08-31 Published:2017-01-12

摘要: 本文对闽北山区两个不同类型疟区的居民,于1976~1981年期间的每年10月随机采集200~400份血标本,检测疟疾间接荧光抗体(IFA)与镜检厚滴血膜疟原虫。结果表明,疟疾的年发病率与当地人群IFA阳性率呈正相关(r_s=0.60,P0.05),而与疟原虫率相关程度较差(r_s=0.38,P0.05)。结果提示,在疟疾传播季节后期人群疟疾荧光抗体水平是监测当年疟疾流行状况的良好指标之一。

关键词: 抗体试验, 间接荧光抗体, 纵向调查, 疟原虫, 疟疾传播, 阳性率, 寄生虫病研究所, 疟疾流行, 年发病率, 中华按蚊

Abstract: This investigation was carried out in two malarious villages of different types In Pucheng County, Fujian during the period of 1976 to 1978. 200-400 blood samples were collected randomly in both villages in October by the end of transmission season in each year. For each sample, immunofluorescent antibody test (IFAT) and blood examination were performed simultaneously. It was found that the malaria incidence was closely related to the positive rate of IFAT (p0.05) but less closely related to the positive parasite rate (p0.05). The results suggested that IFAT is a sensitive index for monitoring the endemicity of malaria during the transmissionseason.