CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES ›› 2019, Vol. 37 ›› Issue (5): 598-602.doi: 10.12140/j.issn.1000-7423.2019.05.016

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Progress in the identification of Paragonimus species by DNA technology

Kun-min HU(), Bin ZHENG*(), Shao-hong CHEN, Ling AI   

  1. National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention;Chinese Center for Tropical Diseases Research;WHO Collaborating Centre for Tropical Diseases;National Center for International Research on Tropical Diseases, Ministry of Science and Technology;Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai 200025, China
  • Received:2019-07-05 Online:2019-10-30 Published:2019-11-07
  • Contact: Bin ZHENG E-mail:2450433288@qq.com;zhengbin@nipd.chinacdc.cn
  • Supported by:
    Supported by the National Science and Technology Major Program of China(No. 2018ZX10734-404)

Abstract:

Paragonimiasis is an important food-borne parasitic disease caused by the infection of Paragonimus spp. through ingestion of the intermediate host crabs, crayfishes contaminated with Paragonimus larvae. The tremotode parasitizes in different tissues and organs of human and other mammals and cause paragonimiasis. China is the country with the most widespread of the disease and diverse species of Paragonimus. Paragonimus infections have been reported in 27 provinces or regions in China. In recent years, the development of molecular biology technology including DNA detection technique has played an important role in the identification of Paragonimus species and strains. However, different DNA detection assays own different detection sensitivity, specificity, detection time and cost. The appropriate DNA detection method should be selected according to the different needs. In this paper, the research progress in the identification of Paragonimus species and strains by the DNA detection assays developed by domestic and international scientists is reviewed in order to provide reference for accelerating the identification Paragonimus species and the diagnosis of paragonimiasis.

Key words: Paragonimus, DNA technology, Taxonomy

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