肝多房棘球蚴病微血管密度的研究进展

摘要/Abstract

摘要：

肝多房棘球蚴病的生物学特性类似于肝恶性肿瘤，手术根治具有一定的困难。目前对肝多房棘球蚴病的诊断水平和治疗手段虽然有所提高，但患者术后复发时有发生，预后情况不容乐观。近年来有研究表明，棘球蚴病灶周围有新生血管生成。为探究病灶的血管供应情况和病灶的生物活性，本文对病灶周围血管分布和血管生成相关因子的表达作一综述。

关键词: 肝多房棘球蚴病, 微血管密度, 血管内皮生长因子

Abstract:

Hepatic alveolar echinococcosis (HAE) is a parasitic disease caused by the larva of Echinococcus multilocularis infection. It is challenging to achieve radical resection because its biological characteristics are similar to malignant liver tumours. Although the diagnosis and treatment of HAE have been improved continuously, lesion recurrence postoperation often occurs, and the prognosis is not optimistic. In recent years, studies have shown that microvascular occurs around HAE lesions. In order to explore the blood supply and biological activity of the lesions, the vascular distribution around the lesions and the expression of angiogenesis-related factors were reviewed in this paper.

Key words: Hepatic alveolar echinococcosis, Microvascular density, Vascular endothelial growth factor

中图分类号:

532.32

安秀青, 王苗苗, 周鸿乾, 孟凯, 蔡剑平, 刘光辉, 阿吉德, 杨金煜. 肝多房棘球蚴病微血管密度的研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2022, 40(6): 792-797.

AN Xiu-qing, WANG Miao-miao, ZHOU Hong-qian, MENG Kai, CAI Jian-ping, LIU Guang-hui, A Ji-de, YANG Jing-yu. Research progress on microvascular density in hepatic alveolar echinococcosis[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2022, 40(6): 792-797.

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