To understand the situation of malaria prevention and control implemented among abroad labor workers as reference for the better control and management of imported malaria, a questionnaire survey was carried out in 2017 on those who returned from abroad or will be dispatched abroad and the administrators in these two companies in Guizhou Province for the knowledge, attitude and behavior (KAP) toward malaria infection and control. Among 242 people surveyed, 182 (75.2%) had experience working abroad, of which 40 (22.0%) had suffered from malaria. Among these migrant workers, the infection incidence of malaria was highest in those with education of middle school or lower (44.4%), with statistical significance among people with different educational levels (P < 0.05). People who worked outdoor had higher malaria incidence (34.5%) than those working indoor with statistical significance (P < 0.05). However, there was no statistical significance in the malaria incidence between the people with acquired malaria control knowledge and without (P > 0.05). People who agreed that antimalarial drugs could prevent malaria had significantly lower malaria incidence (15.7%) than those who did not agree (42.9%)(P < 0.05). Regarding the protection behavior, people who used mosquito nets had much lower malaria incidence (1.4%) than those who did not (35.8%) with statistical significance between them (P < 0.05). The similar result was seen in the usage of mosquito repellents, people who used had significantly lower malaria incidence (12.1%) than those who did not (27.3%)(P < 0.05). People who took prophylactic medication had significantly lower malaria incidence (13.0%) than those who did not (59.0%) (P < 0.05). Multivariate logistic regression analysis demonstrated that the risk factors for malaria infection include the lack of use of mosquito nets (OR = 69.075, CI = 7.187-663.904), lack of taking preventive medicine (OR = 17.602, CI = 4.754-65.173). The attitude towards agreement to use anti-malarial drugs was beneficial for preventing malaria (OR = 0.119, CI = 0.034-0.423). Lack of mosquito net usage and without taking preventive medicine are the big risk factors for malaria infection in endemic areas when working abroad.