Malaria case investigation forms in 31 provinces/municipalities/autonomous regions (excluding Taiwan, Hongkong, Macao) and the Xinjiang Production and Construction Corps aross China in 2025 were collected from the National Notifiable Infectious Diseases Reporting Information System, and the epidemiological characteristic of malaria cases were statistically analyzed. A total of 4 314 malaria cases were reported in China in 2025, which increased by 50.8%, 439.9%, and 36.6% relative to in 2017 (2 861), 2021 (799) and 2024 (3 157), respectively, and 11 deaths were reported in 2025, which reduced by four as compared to in 2024 (15 deaths). Of all reported malaria cases, there were 2 829 Plasmodium falciparum malaria cases (65.6%, 2 829/4 314), 963 P. vivax malaria cases (22.3%. 963/4 314), 372 P. ovale malaria cases (8.6%, 372/4 314), 103 P. malariae malaria cases (2.4%,103/4 314), and 47 cases with mixed infections (1.1%, 47/4 314), and there were 4 308 imported cases, 5 non-mosquito-borne malaria cases (transfusion-transmitted infection), and one recrudescent case with a long incubation period (P. malariae malaria). Malaria cases were reported in 30 provinces and the Xinjiang Production and Construction Corps, with the exception of Xizang Autonomous Region, with Yunnan Province (678 cases), Guangdong Province (359 cases), Henan Province (354 cases), Hunan Province (338 cases), and Shandong Province (307 cases) as the five most seriously affected provinces, accounting for 47.2% (2 036/4 314) of totally reported malaria cases. The ratio of male to female cases was 12.8 ∶ 1, and patients at ages of 30 to 39 years accounted for the largest proportion of cases (29.1%, 1 255/4 314). The most common reason for exit and entry was labor (71.6%, 3 086/4 308). A total of 131 critically ill malaria cases were reported across 27 provinces in 2025 (3.0%, 131/4 314), which increased by 17.0% relative to in 2024 (112 cases). Malaria epidemic has risen for four consecutive years in China, and thousands of imported malaria cases have posed substantial pressure and challenges to prevention of re-establishment of imported malaria.