CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES >

2025 , Vol. 43 >Issue 5: 683 - 689

DOI: https://doi.org/10.12140/j.issn.1000-7423.2025.05.013

ORIGINAL ARTICLES

Epidemiological characteristics of scrub typhus in Dehong Dai and Jingpo Autonomous Prefecture, Yunnan Province from 2010 to 2024

  • GOU Changchun ,
  • LIU Aicong ,
  • FENG Kai ,
  • CAO Chunli ,
  • SONG Xiaoxiao ,
  • YUE Taike
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  • 1 Dehong Dai and Jingpo Autonomous Prefecture Center for Disease Control and Prevention, Mangshi 678400, Yunnan, China
    2 National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases; NHC Key Laboratory on Parasite and Vector Biology; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai 200025, China
    3 Department of Epidemiology and Statistics, School of Public Health, Kunming Medical University, Kunming 650500, Yunnan, China

Received date: 2025-04-02

  Revised date: 2025-06-10

  Online published: 2025-10-14

Supported by

Yunnan Provincial Science and Technology Department-Kunming Medical University Joint Applied Basic Research Project(202301AY070001-259);Key Laboratory of Public Health & Disease Prevention and Control of Yunnan Provincial Education Department(2023ZD08)

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Abstract

Objective To investigate the epidemiological characteristics of scrub typhus in Dehong Dai and Jingpo Autonomous Prefecture, Yunnan Province from 2010 to 2024, so as to provide insights into optimization of scrub typhus control strategies. Methods Data on scrub typhus cases reported in Dehong from January 1, 2010, to December 31, 2024 were collected from the China Disease Prevention and Control Information System. The Joinpoint Regression Program version 5.3.0 was used to establish a Joinpoint regression model. The annual percent change (APC), average annual percent change (AAPC), and their 95% confidence intervals (CI) of the incidence of reported scrub typhus were calculated to analyze the trends in incidence by gender, region, and age group. Normality tests and descriptive statistical analyses were performed using the software SPSS 25.0. Results A total of 13 715 scrub typhus cases were reported in Dehong from 2010 to 2024, with no deaths, and the annual average reported incidence was 71.88/105. The number of reported cases and reported incidence appeared an overall tendency towards a rise from 2010 to 2022, with an increase from 117 cases (9.84/105) in 2010 to 1 817 cases (138.76/105) in 2022. A slight decline was observed in 2023 (1 644 cases, 124.47/105) and 2024 (1 457 cases, 108.97/105), although the incidence remained high. There were significant differences in the number of reported cases and the incidence among years (χ2 = 5 318.62, 4 783.42; both P < 0.01). Joinpoint regression analysis identified two turning points (in 2016 and 2022) and the trends in incidence were divided into three phases: a significant increase from 2010 to 2016 (APC = 33.61%, P < 0.01), a continued but slower increase from 2017 to 2022 (APC = 13.94%, P < 0.01), and a numerical decline from 2023 to 2024 (APC = -10.74%, P > 0.05). Mangshi, Yingjiang County and Longchuan County were high-incidence areas from 2010 to 2024, with 4 826 (35.19%), 3 921 (28.59%), and 3 151 (22.97%) reported cases, and average annual incidence rates of 77.57/105, 84.83/105, and 112.80/105, respectively. Joinpoint regression analysis indicated that the reported incidence appeared a tendency towards a significant rise across all counties (cities) from 2010 to 2024 (all P < 0.01 for AAPC), with the largest increase seen in Lianghe County (AAPC = 48.00%), followed by Longchuan County (AAPC = 38.64%), Ruili City (AAPC = 22.57%), Mangshi (AAPC = 18.47%), and Yingjiang County (AAPC = 9.14%). A distinct seasonal pattern was observed in the incidence, with the peak in August (seasonal index = 2.65). The epidemic season was found from July to November, with the number of reported cases accounting for 84.81% (11 632/13 715) of the total reported cases. There were 7 799 (56.86%) male cases and 5 916 (43.14%) female cases, with a male-to-female ratio of 1.32 : 1, and the trends in incidence among both genders were consistent with the overall trend, with 2016 and 2022 as key turning points. Cases were widely distributed across all age groups, ranging from 1 month to 96 years, with a median age of 40 years. The majority of cases (55.49%, 7 611/13 715) were young and middle-aged adults aged 30 to 59 years. Joinpoint regression analysis revealed a significant increase in incidence across all age groups from 2010 to 2024 (all P < 0.01 for AAPC), with the largest increase seen among residents at ages of 40 to 49 years (AAPC = 19.41%, 95% CI: 17.36 to 24.60). Farmers were the dominant occupation (9 969 cases, 72.69%). Conclusion The incidence of scrub typhus appeared an overall tendency towards a rapid rise in Dehong from 2010 to 2024. Continuous improvements of disease surveillance and control is recommended tailored to high-risk regions, epidemic seasons, and high-risk populations.

Key words： Scrub typhus; Epidemiological characteristic; Temporal trend; Joinpoint regression analysis

Cite this article

GOU Changchun , LIU Aicong , FENG Kai , CAO Chunli , SONG Xiaoxiao , YUE Taike . Epidemiological characteristics of scrub typhus in Dehong Dai and Jingpo Autonomous Prefecture, Yunnan Province from 2010 to 2024[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2025 , 43(5) : 683 -689 . DOI: 10.12140/j.issn.1000-7423.2025.05.013

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