CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES >
Changes in the epidemiological characteristics and control progress of soil-transmitted nematodiasis in Hainan Island
Received date: 2024-08-22
Revised date: 2024-11-30
Online published: 2025-04-21
Supported by
Health Science & Technology Joint Program in Hainan Province(WSJK2024MS167)
Hainan Island locates in tropical regions of China, and the climatic and natural environmental conditions are feasible for transmission of multiple types of soil-transmitted nematodiases. This review summarizes the changes in the prevalence of soil-transmitted nematode infections, soil-transmitted nematodiasis control measures and the effectiveness of these control measures in Hainan Island during the past 70 years. The prevalence of soil-transmitted nematode human infections decreased from 94.7% in 1991 to 4.1% in 2023 in Hainan Island. Results from three national surveys on human parasitic diseases and provincial disease surveillance programmes showed a higher prevalence rate of soil-transmitted nematode infections in central mountainous regions than in other regions, a higher prevalence rate among women than among men, a higher prevalence rate among children at ages of 5 to 9 years, adolescents at ages of 10 to 14 years and the elderly at ages of 60 to 69 years and 70 years and greater than among resident at other age groups, and a higher prevalence rate among farmers, students and preschool children than among humans with other occupations. There are three stages of soil-transmitted nematodiasis control programmes in Hainan Island, including small-scale mass examinations and treatment, large-scale mass prevention and treatment, and prevention and treatment of high-risk populations, and the major control measures included large-scale surveys on parasitic infections, mass drug administration, improvements in water and sanitation, health education, and pilot construction of demonstration areas. Currently, the prevalence of soil-transmitted nematode infections is low in Hainan Island; however, sustainable control programmes are required to achieve transmission control and interruption of soil-transmitted nematodiasis. Future multiple control efforts are recommended, including expansion of surveillance regions, to achieve precision control of soil-transmitted nematodiasis.
XU Guangda , ZENG Wen , HUANG Xiaomin , LI Yuchun . Changes in the epidemiological characteristics and control progress of soil-transmitted nematodiasis in Hainan Island[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2025 , 43(2) : 252 -259 . DOI: 10.12140/j.issn.1000-7423.2025.02.016
| [1] | Montresor A, Mupfasoni D, Mikhailov A, et al. The global progress of soil-transmitted helminthiases control in 2020 and World Health Organization targets for 2030[J]. PLoS Negl Trop Dis, 2020, 14(8): e0008505. |
| [2] | Working to overcome the global impact of neglected tropical diseases—Summary[J]. Wkly Epidemiol Rec, 2011, 86(13): 113-120. |
| [3] | 诸欣平, 苏川. 人体寄生虫学[M]. 9版. 北京: 人民卫生出版社, 2013: 167-172. |
| Zhu XP, Su C. Human parasitology[M]. 9th edition. Beijing: People’s Medical Publishing House, 2013: 167-172. (in Chinese) | |
| [4] | 尚煜, 汤林华. 土源性线虫感染及对儿童健康影响的研究进展[J]. 中国儿童保健杂志, 2010, 18(6): 505-507. |
| Shang Y, Tang LH. Research progress on soil-transmitted nematode infection and its influence on children’s health[J]. Chin J Child Health Care, 2010, 18(6): 505-507. (in Chinese) | |
| [5] | Lai YS, Zhou XN, Utzinger J, et al. Bayesian geostatistical modelling of soil-transmitted helminth survey data in the People’s Republic of China[J]. Parasit Vectors, 2013, 6: 359. |
| [6] | 吴胜安, 邢彩盈, 朱晶晶. 海南岛气候特征分析[J]. 热带生物学报, 2022, 13(4): 315-323. |
| Wu SA, Xing CY, Zhu JJ. Analysis of climate characteristics in Hainan Island[J]. J Trop Biol, 2022, 13(4): 315-323. (in Chinese) | |
| [7] | Bercovitz N. Tropical diseases in relation to general health in Hainan, China[J]. J Trop Med, 1935, 12(3): 45-50. |
| [8] | Oldt F. Night-soil as fertilizer[J]. Chin Med J, 1926, 40(11): 1059-1070. |
| [9] | Oldt F. Hookworm in Kwong Tung and some suggestions for its eradication[J]. Chin Med J, 1926, 40(3): 240-248. |
| [10] | 江静波, 陈俊民, 李定华. 海南岛万宁县国营农场钩虫病的调查[J]. 中山大学学报(自然科学版), 1957, 3(2): 96-128. |
| Jiang JB, Chen JM, Li DH. Investigation on hookworm disease in a state farm in Wanning County, Hainan Island[J]. Acta Sci Nat Univ Sun Yatseni, 1957, 3(2): 96-128. (in Chinese) | |
| [11] | 林绍雄, 王善青, 胡锡敏, 等. 海南省中部山区土源性线虫感染情况[J]. 中国寄生虫学与寄生虫病杂志, 2010, 28(2): 160-161. |
| Lin SX, Wang SQ, Hu XM, et al. Epidemiology of soil-transmitted nematode infections in central mountain area of Hainan Province[J]. Chin J Parasitol Parasit Dis, 2010, 28(2): 160-161. (in Chinese) | |
| [12] | 云昌扶, 罗智梅. 海南岛北港流行性哮喘调查及其病因探讨[J]. 广东医学, 1964, (S3): 122-124. |
| Yun CF, Luo ZM. Investigation on epidemic asthma in Beigang, Hainan Island and its etiology[J]. Guangdong Med J, 1964, (S3): 122-124. (in Chinese) | |
| [13] | 朱师晦. 在农村开展肠道寄生虫病普查普治工作报告[J]. 广东医学(现代医学版), 1965, (S5): 265-266. |
| Zhu SH. Report on the general survey and treatment of intestinal parasitic diseases in rural areas[J]. Guangdong Med J, 1965, (S5): 265-266. (in Chinese) | |
| [14] | 徐凤翙, 吴让庄, 陈绩彰, 等. 海南省人体寄生虫分布调查[J]. 中国寄生虫学与寄生虫病杂志, 1994, 12(S1): 32-36. |
| Xu FH, Wu RZ, Chen JZ, et al. Investigation on human parasite distribution in Hainan Province[J]. Chin J Parasitol Parasit Dis, 1994, 12(S1): 32-36. (in Chinese) | |
| [15] | 余森海, 许隆祺, 蒋则孝, 等. 首次全国人体寄生虫分布调查的报告Ⅰ. 虫种的地区分布[J]. 中国寄生虫学与寄生虫病杂志, 1994, 12(4): 241-247. |
| Yu SH, Xu LQ, Jiang ZX, et al. Report on the first nationwide survey of the distribution of human parasites in ChinaⅠ. regional distribution of parasite species[J]. Chin J Parasitol Parasit Dis, 1994, (4): 241-247. (in Chinese) | |
| [16] | 胡锡敏, 王善青, 林绍雄, 等. 海南省人体重要寄生虫病现状调查[J]. 中国热带医学, 2006, 6(5): 763-765, 749. |
| Hu XM, Wang SQ, Lin SX, et al. The investigation of situation of principal human parasitic diseases in Hainan Province[J]. China Trop Med, 2006, 6(5): 763-765, 749. (in Chinese) | |
| [17] | 许隆祺, 陈颖丹, 孙凤华, 等. 全国人体重要寄生虫病现状调查报告[J]. 中国寄生虫学与寄生虫病杂志, 2005, 23(S1): 332-340. |
| Xu LQ, Chen YD, Sun FH, et al. A national survey on current status of the important parasitic diseases in human population[J]. Chin J Parasitol Parasit Dis, 2005, 23(S1): 332-340. (in Chinese) | |
| [18] | 孙定炜, 刘莹, 王光泽, 等. 2015年海南省人体重点寄生虫感染现状调查[J]. 中国寄生虫学与寄生虫病杂志, 2019, 37(3): 254-259. |
| Sun DW, Liu Y, Wang GZ, et al. Endemic status of human important parasitic infection in Hainan Province, China in 2015[J]. Chin J Parasitol Parasit Dis, 2019, 37(3): 254-259. (in Chinese) | |
| [19] | 陈颖丹, 周长海, 朱慧慧, 等. 2015年全国人体重点寄生虫病现状调查分析[J]. 中国寄生虫学与寄生虫病杂志, 2020, 38(1): 5-16. |
| Chen YD, Zhou CH, Zhu HH, et al. National survey on the current status of important human parasitic diseases in China in 2015[J]. Chin J Parasitol Parasit Dis, 2020, 38(1): 5-16. (in Chinese) | |
| [20] | 童重锦, 吴让庄, 徐风翙, 等. 海口市中小学生人体肠道寄生虫感染情况的调查[J]. 海南医学, 1995, 6(2): 82-83, 72. |
| Tong CJ, Wu RZ, Xu FH, et al. Investigation on human intestinal parasite infection among primary and middle school students in Haikou City[J]. Hainan Med J, 1995, 6(2): 82-83, 72. (in Chinese) | |
| [21] | 陈绩彰, 徐凤翙, 吴让庄, 等. 海南省农村小学生肠道寄生虫感染情况的调查[J]. 中国学校卫生, 1995, 16(3): 212-213. |
| Chen JZ, Xu FH, Wu RZ, et al. Investigation on intestinal parasite infection of rural primary school students in Hainan Province[J]. Chin J Sch Health, 1995, 16(3): 212-213. (in Chinese) | |
| [22] | 陈绩彰, 黄定良, 曾文, 等. 控制土源性线虫病的防治措施研究[J]. 广西预防医学, 1998, (1): 26-27. |
| Chen JZ, Huang DL, Zeng W, et al. Study on control measures of soil-borne nematodiasis[J]. Guangxi Prey Med, 1998, (1): 26-27. (in Chinese) | |
| [23] | 胡锡敏, 李善文, 童重锦. 海南省部分市县人体肠道寄生虫感染基线调查结果分析[J]. 海南医学, 2001, 12(10): 77-78. |
| Hu XM, Li SW, Tong CJ. Analysis on baseline survey of human intestinal parasite infection in some counties, Hainan Province[J]. Hainan Med J, 2001, 12(10): 77-78. (in Chinese) | |
| [24] | 黄捷敏, 陈冬燕, 刘姚若, 等. 海南临高县人体重要寄生虫病现状调查[J]. 中国热带医学, 2009, 9(11): 2143-2144. |
| Huang JM, Chen DY, Liu YR, et al. Survey of major human parasitosis in Lingao County,Hainan[J]. China Trop Med, 2009, 9(11): 2143-2144. (in Chinese) | |
| [25] | 童重锦, 王善青, 胡锡敏, 等. 海南西部地区人体肠道寄生虫感染现状调查[J]. 寄生虫与医学昆虫学报, 2006, 13(3): 139-143. |
| Tong CJ, Wang SQ, Hu XM, et al. Investigation on the infection of human intestinal parasitic diseases in western regions of Hainan Province[J]. Acta Parasitol Med Entomol Sin, 2006, 13(3): 139-143. (in Chinese) | |
| [26] | 王丹丹. 中国土源性线虫病流行状况与危险因素分析[D]. 长沙: 中南大学, 2013: 28-29. |
| Wang DD. Report on soil-transmitted helminths infection and its risk factors in People’s Republic of China[D]. Changsha: Central South University, 2013: 28-29. (in Chinese) | |
| [27] | 林绍雄, 王善青, 胡锡敏, 等. 海南省土源性线虫病流行现状分析[J]. 中国热带医学, 2010, 10(8): 939-941. |
| Lin SX, Wang SQ, Hu XM, et al. Analysis of prevalent status of soil-borne nemathelminthiasis in Hainan Province[J]. China Trop Med, 2010, 10(8): 939-941. (in Chinese) | |
| [28] | 林绍雄, 王善青, 胡锡敏, 等. 海南省中部地区人体重要寄生虫病的现状调查[J]. 中国热带医学, 2005, 5(7): 1417-1419, 1455. |
| Lin SX, Wang SQ, Hu XM, et al. Survey of infectious status of main human parasites in central area of Hainan Province[J]. China Trop Med, 2005, 5(7): 1417-1419, 1455. (in Chinese) | |
| [29] | 张米禛, 黄继磊, 朱慧慧, 等. 2020年全国人体土源性线虫感染情况分析[J]. 中国寄生虫学与寄生虫病杂志, 2023, 41(3): 331-335, 343. |
| Zhang MZ, Huang JL, Zhu HH, et al. Epidemiological analysis of soil-transmitted nematode infections in China in 2020[J]. Chin J Parasitol Parasit Dis, 2023, 41(3): 331-335, 343. (in Chinese) | |
| [30] | 朱慧慧, 黄继磊, 陈颖丹, 等. 2019年全国土源性线虫感染状况分析[J]. 中国寄生虫学与寄生虫病杂志, 2021, 39(5): 666-673. |
| Zhu HH, Huang JL, Chen YD, et al. Analysis on endemic status of soil-transmitted nematode infection in China in 2019[J]. Chin J Parasitol Parasit Dis, 2021, 39(5): 666-673. (in Chinese) | |
| [31] | 朱慧慧, 黄继磊, 诸廷俊, 等. 2017年全国土源性线虫感染监测数据分析[J]. 中国寄生虫学与寄生虫病杂志, 2019, 37(1): 12-17. |
| Zhu HH, Huang JL, Zhu TJ, et al. National surveillance of soil-transmitted helminth infections in 2017[J]. Chin J Parasitol Parasit Dis, 2019, 37(1): 12-17. (in Chinese) | |
| [32] | Zhu HH, Huang JL, Zhou CH, et al. Soil-transmitted helminthiasis—China, 2018[J]. China CDC Wkly, 2020, 2(3): 34-38. |
| [33] | 陈伟奇, 蒋甜甜, 邓艳, 等. 河南省两次重点寄生虫病调查中土源性线虫感染影响因素差异分析[J]. 现代预防医学, 2023, 50(19): 3618-3623. |
| Chen WQ, Jiang TT, Deng Y, et al. Analysis on the difference of influencing factors of soil-borne nematode infection in two key parasitic diseases surveys in Henan Province[J]. Mod Prev Med, 2023, 50(19): 3618-3623. (in Chinese) | |
| [34] | 金伟, 郭见多, 张世清, 等. 安徽省土源性线虫病流行特征及相关因素分析[J]. 中华疾病控制杂志, 2018, 22(10): 1041-1045. |
| Jin W, Guo JD, Zhang SQ, et al. Distribution and risk factors of soil-transmitted nematode diseases in Anhui Province[J]. Chin J Dis Control Prev, 2018, 22(10): 1041-1045. (in Chinese) | |
| [35] | 邵利业, 陈观升, 王孝正, 等. 河南省商丘市土源性线虫感染情况及影响因素分析[J]. 河南预防医学杂志, 2021, 32(8): 603-605. |
| Shao LY, Chen GS, Wang XZ, et al. Analysis of infection level of soil-born nematodes and its influencing factors in Shangqiu City, Henan Province[J]. Henan J Prev Med, 2021, 32(8): 603-605. (in Chinese) | |
| [36] | Fauziah N, Ar-Rizqi MA, Hana S, et al. Stunting as a risk factor of soil-transmitted helminthiasis in children: A literature review[J]. Interdiscip Perspect Infect Dis, 2022, 2022: 8929025. |
| [37] | 汤林华, 许隆祺, 陈颖丹. 中国寄生虫病防治与研究[M]. 北京: 北京科学技术出版社, 2012: 1291-1306. |
| Tang LH, Xu LQ, Chen YD. Parasitic disease control and research in China[M]. Beijing: Beijing Science & Technology Press, 2012: 1291-1306. (in Chinese) | |
| [38] | 韦少成, 林诗泉, 杨才绩. 海南省卫生事业发展50年史:1950—2000[M]. 海口: 南方出版社, 2007: 320-354. |
| Wei SC, Lin SQ, Yang CJ. The 50-year history of health development in Hainan Province: 1950-2000[M]. Haikou: Southern Publishing House, 2007: 320-354. (in Chinese) | |
| [39] | 云昌扶, 陈绩彰, 马汉彩, 等. 苦楝根皮配合枸椽酸哌嗪驱蛔81例疗效初步报告[J]. 广东医学(祖国医学版), 1964(2): 24-26. |
| Yun CF, Chen JZ, Ma HC, et al. Preliminary report on the curative effect of neem root bark combined with piperazine citrate on 81 cases[J]. Guangdong Med J, 1964(2): 24-26. (in Chinese) | |
| [40] | 云昌扶. 大剂量维生素C为主治疗胆道蛔虫42例的疗效报告(摘要): 附内科综合治疗33例对照比较[J]. 广东医药资料, 1978, (10): 48-49. |
| Yun CF. A report on the curative effect of high-dose vitamin C on 42 cases of biliary Ascaris (abstract): A comparative study of 33 cases of comprehensive treatment in internal medicine[J]. Guangdong Med J, 1978, (10): 48-49. (in Chinese) | |
| [41] | 陈代熙. 用花生油佐治小儿蛔虫性肠梗阻18例观察[J]. 中国农村医学, 1994, 22(9): 41. |
| Chen DX. Observation on 18 cases of Ascaris intestinal obstruction in children treated with peanut oil[J]. Chin J Clin, 1994, 22(9): 41. (in Chinese) | |
| [42] | 卫生部、 国家教委. 全国学生常见肠道蠕虫感染综合防治方案(试行)[J]. 中国学校卫生, 1992, 13(2): 78-79. |
| Ministry of Health and State Education Commission. Comprehensive prevention and control scheme for common intestinal helminth infections among students in China (for trial implementation)[J]. Chin J Sch Health, 1992, 13(2): 78-79. (in Chinese) | |
| [43] | 吴英友. 海南省农垦中小学生驱虫情况及驱虫效果调查[J]. 中国热带医学, 2002, 2(3): 427-428. |
| Wu YY. Investigation into results of deworming in primary pupils and middle school students of Hainan Land Reclamation Bureau[J]. China Trop Med, 2002, 2(3): 427-428. (in Chinese) | |
| [44] | 崔宜庆. 海南省寄生虫病防治现状、 问题与建议[J]. 中国热带医学, 2001, 1(1): 54-57. |
| Cui YQ. Present situation, problems and suggestions of parasitic diseases control in Hainan Province[J]. China Trop Med, 2001, 1(1): 54-57. (in Chinese) | |
| [45] | 张倩, 陈颖丹, 许隆祺, 等. 我国土源性线虫病综合防治示范区3年防治效果[J]. 中国血吸虫病防治杂志, 2011, 23(5): 476-482. |
| Zhang Q, Chen YD, Xu LQ, et al. Effect of control on infections of soil-transmitted helminthes in demonstration plots of China for 3 years[J]. Chin J Schisto Control, 2011, 23(5): 476-482. (in Chinese) | |
| [46] | 陈颖丹, 臧炜. 我国土源性线虫病监测现状及今后监测工作重点[J]. 中国血吸虫病防治杂志, 2015, 27(2): 111-114. |
| Chen YD, Zang W. Current situation of soil-transmitted nematodiasis monitoring in China and working keys in future[J]. Chin J Schisto Control, 2015, 27(2): 111-114. (in Chinese) | |
| [47] | 陈颖丹, 朱慧慧, 黄继磊, 等. 我国土源性线虫病流行现状及新时期防控原则[J]. 中国血吸虫病防治杂志, 2019, 31(1): 23-25. |
| Chen YD, Zhu HH, Huang JL, et al. Status and working principals of soil-transmitted nematodiasis during new period in China[J]. Chin J Schisto Control, 2019, 31(1): 23-25. (in Chinese) | |
| [48] | Malecela MN, Ducker C. A road map for neglected tropical diseases 2021-2030[J]. Trans R Soc Trop Med Hyg, 2021, 115(2): 121-123. |
| [49] | 国家卫生标准委员会寄生虫病标准专业委员会. 土源性线虫病的传播控制与阻断: WS/T 629—2018[S]. 北京: 中国标准出版社, 2018: 2. |
| National Health Standards Committee Professional Committee on Parasitic Disease Standards. Criteria for transmission control and interruption of soil-transmitted nematodiasis: WS/T 629-2018[S]. Beijing: China Standards Publishing House, 2018: 2. (in Chinese) |
/
| 〈 |
|
〉 |