CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES >

2024 , Vol. 42 >Issue 5: 659 - 663

DOI: https://doi.org/10.12140/j.issn.1000-7423.2024.05.015

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Analysis of the current status of Clonorchis sinensis infection in Xinfeng County, Jiangxi Province from 2020 to 2022

  • LAN Weiming ,
  • ZENG Yufeng ,
  • QIU Tingting ,
  • ZHOU Changhai ,
  • CHEN Zhe ,
  • GE Jun ,
  • ZENG Xiaojun ,
  • ZHU Tingjun
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  • 1 Jiangxi Provincial Institute of Parasitic Diseases, Nanchang 330096, Jiangxi, China
    2 Xinfeng County Center for Disease Control and Prevention, Ganzhou 341600, Jiangxi, China
    3 National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases; Key Laboratory on Parasite and Vector Biology, Ministry of Health; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai 200025, China

Received date: 2024-03-07

  Revised date: 2024-07-15

  Online published: 2024-08-09

Supported by

Jiangxi Province Key Laboratory Project(20192BCD40006);Science and Technology Planning Project of Jiangxi Health Commission(202311186)

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Abstract

In order to understand the current situation of Clonorchis sinensis infection in Xinfeng County, Jiangxi Province, Xinfeng County was divided into 5 sectors (east, west, south, north and central) according to the geographical location. From each sector, 1 administrative village in 1 township (town) was selected as surveillance site, and no less than 200 permanent residents aged 3 or above were selected by cluster random sampling from each surveillance site in every year. Fecal samples were collected and examined for eggs of C. sinensis by modified Kato-Katz thick smear method (two slides per sample). The infected cases were treated with praziquantel (75 mg/kg) for 2 days, and examined for eggs of C. sinensis one month after treatment. The infection rate was compared by Chi-square test. The total infection rate of C. sinensis was 6.43% (202/3 142) in Xinfeng County from 2020 to 2022, and the annual infection rates were 6.09% (61/1 002), 5.11% (52/1 017) and 7.93% (89/1 123), respectively (χ2 = 7.30, P < 0.05). The infection rate of males (8.30%, 134/1 614) was higher than females (4.45%, 68/1 528) (χ2 = 19.36, P < 0.01). The infection rates of the elderly groups over 40 years old (7.87%, 168/2 134) was higher than that of the younger age groups (3.37%, 34/1 008) (χ2 = 23.04, P < 0.01). The groups with the highest infection rates were college and above in 2020 (1/8), junior high school in 2021 (6.02%, 15/249) and illiteracy in 2022 (11.36%, 30/264), respectively. The infected cases originated from 176 households, and the proportions of households with 1, 2 and 4 infected cases were 87.50% (154/176), 11.36% (20/176) and 1.14% (2/176), respectively. After praziquantel treatment, 197 infected cases achieved negative in fecal test, among them 2 cases turned positive after 1 year and 10 cases turned positive after 2 years. The reinfection rate was 6.09% (12/197). The results indicated that the prevention and control situation for clonorchiasis in Xinfeng County, Jiangxi Province was still severe. The infection rates were relatively high in some administrative villages, with familial clustering of infection and individual reinfection.

Key words： Clonorchis sinensis; Infection status; Family infection; Reinfection; Jiangxi Province

Cite this article

LAN Weiming , ZENG Yufeng , QIU Tingting , ZHOU Changhai , CHEN Zhe , GE Jun , ZENG Xiaojun , ZHU Tingjun . Analysis of the current status of Clonorchis sinensis infection in Xinfeng County, Jiangxi Province from 2020 to 2022[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2024 , 42(5) : 659 -663 . DOI: 10.12140/j.issn.1000-7423.2024.05.015

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