Objective To analyze the epidemic characteristics and influencing factors of Taenia infection and cysticercus antibody in the residents of Dali, Yunnan, to provide a scientific basis for prevention and control of taeniasis and cysticercosis. Methods From October to November 2023, a survey was conducted in Dabaguan Village, Huoshan Village, Jingang Village and Qingshuigou Village in the historical endemic area of taeniasis and cysticercosis in Dali Prefecture. Permanent residents aged over 3 years were enrolled in the survey using the method of cluster random sampling. A questionnaire survey was conducted to collect information including whether there was a history of proglottid excreted, subcutaneous nodules, symptoms of epilepsy and severe headache, as well as the dietary habits, hygiene behaviors and living environment. Fecal samples were collected, and examined by the modified Kato-Katz method (two slide-reading for each sample). For residents with positive fecal test results or with a history of excreting proglottids in the past year, pharmacological diagnostic deworming was conducted using the areca-pumpkin seed method. Those positives in fecal examination and found expelled worms were considered as the infected persons and used to calculate the infection rate. Serum cysticercus specific antibodies were detected using cysticercus (Taenia solium) IgG antibody detection kit. The chi-square test, Fisher’s exact probability method and logistic regression analysis were used to analyze the influencing factors of Taenia infection and serum cysticercus antibody positivity in the population. Results A total of 1 842 people from the 4 villages participated in the questionnaire survey, and 39 people (2.1%) had excreted proglottids in the past year. Fecal examination was performed on 1 533 people, and 25 people (1.6%) were found positive. A total of 39 people received diagnostic deworming, and 33 people expelled complete worms (1 person positive in fecal examination did not expel the parasite), and the infection rate was 1.8% (34/1 842). The infection rates in the Jingang, Huoshan, Dabaguan and Qingshuigou villages were 2.1% (10/475), 1.3% (6/450), 2.7% (12/450) and 1.3% (6/467), respectively, with no significant difference (χ² = 3.31, P > 0.05). The infection rate was 2.6% (22/848) in males and 1.2% (12/994) in females (χ² = 4.90, P < 0.05). The infection rates of the 30-59 age group (2.8%, 24/862), Miao (1/2), and farmers and herdsmen (3.0%, 28/944) were the highest in each group (χ² = 10.10, P < 0.01; Fisher = 26.04, P < 0.01; χ² = 13.47, P < 0.01). The positive rate of serum cysticercus antibody was 9.2% (82/887). Positive rates of serum antibodies in Qingshuigou, Dabaguan, Huoshan and Jingang villages were 12.7% (20/157), 4.7% (11/236), 10.4% (26/251) and 10.3% (25/243), respectively, with significant differences (χ² = 8.88, P < 0.05). The positive rates in males were 9.2% (36/393) and 9.3% (46/494) in females (χ² = 0.01, P > 0.05). The serum antibody positive rates in the groups aged 60 years and above (2.8%, 24/862), farmers and herdsmen (11.2%, 61/546) and illiterate people (15.0%, 35/234) were the highest in each group (χ² = 8.66, 12.37, 6.47, P < 0.05 or 0.01). The results of univariate analysis showed that gender, age, nationality, occupation and consuming raw pork products (raw pig skin, pork and liver) were the influencing factors of Taenia infection (χ² = 4.86, 10.10, 26.04, 13.48, 5.72, all P < 0.05). There was a positive correlation between the frequency of consuming raw pork products per month and Taenia infection rate[OR = 1.135, 95% CI: (1.023, 1.259)]. The age, education level, occupation, use of tap water and consuming raw pork products were influencing factors for the positive rate of serum cysticercus antibody (χ² = 8.66, 12.37, 6.47, 3.58, 2.20, all P < 0.05). The results of multivariate analysis showed that males [OR = 2.047, 95% CI: (1.001, 4.189) ] and eating raw pork products [OR = 4.986, 95% CI: (1.166, 21.321) ] were the risk factors for Taenia infection. The low education level [OR = 2.051, 95% CI: (1.183, 3.557)] was a risk factor for positive serum cysticercus antibody, while using tap water [OR = 0.320, 95% CI: (0.124, 0.824) ] was a protective factor for positive serum cysticercus antibody. Conclusion Considerably high Taenia infection rate and positive rate of serum cysticercus antibody are observed in the residents of Dali, Yunnan. Eating raw pork products and male gender are the risk factors for Taenia infection; using tap water and high education level are the protective factors for positive serum cysticercus antibody.