CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES >

2024 , Vol. 42 >Issue 2: 182 - 190

DOI: https://doi.org/10.12140/j.issn.1000-7423.2024.02.008

ORIGINAL ARTICLES

Assessment of the quality of life of patients with echinococcosis in Gansu Province pre- and post-surgery based on the EQ-5D-5L questionnaire

  • LIU Zehang ,
  • ZHANG Xiaojuan ,
  • YANG Guobing ,
  • LEI Jiaxi ,
  • LIU Baixue ,
  • WANG Ying ,
  • WANG Zhiyi ,
  • WANG Dong ,
  • FENG Yu ,
  • WANG Liying
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  • 1 National Institute of Parasitic Diseases, Chinese Centre for Disease Control and Prevention; Chinese Centre for Tropical Diseases Research; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases; Key Laboratory of Parasite and Vector Biology, Ministry of Health; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai 200025, China
    2 Gansu Provincial Center for Disease Control and Prevention, Lanzhou 730000, China

Received date: 2024-01-02

  Revised date: 2024-01-24

  Online published: 2024-04-22

Supported by

National Natural Science Foundation of China(81703281);Gansu Province Health Industry Scientific Research Plan Project(GSWSKY2017-19);NHC Key Laboratory of Echinococcosis Prevention and Control, China(2021WZK1006);Chinese Center for Disease Control and Prevention, Institute of Parasitic Diseases Prevention and Control, Science and Technology Innovation Support Program(TF2024005)

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Abstract

Objective To analyse the changes in quality of life of patients with echinococcosis in Gansu Province pre- and post-surgery, and evaluate the impact of surgical treatments on the patients’ quality of life. Methods The patients with echinococcosis underwent surgery and were managed under the National Project for Echinococcosis Control and Prevention in Gansu Province were surveyed using questionnaire and EQ-5D-5L questionnaire to collect basic information, first visit record, surgical performance, and the quality of life pre- and post-surgery. The data were analyzed by SPSS 19.0 and Origin 2021. Results A total of 856 cases collected, including 417 males and 439 females. The age ranges from 7 to 85 years, with an average of 53 years. There were 737 cases of CE patients, 14 cases of AE patients, and 105 cases of unclassified patients. The longest time from the first surgery to postoperative follow-up for patients with echinococcosis was 17.5 years, and the shortest was 1 month. The average time interval between the investigation and the first surgery was 7.4 years (89 months). The preoperative and postoperative health utility values for patients with echinococcosis were 0.910 ± 0.142 and 0.967 ± 0.067, respectively, showing a 6.3% improvement postsurgery (Z = -12.081, P < 0.05). The preoperative and postoperative visual analog scale (VAS) scores were 79.10 ± 16.00 and 86.25 ± 11.64, respectively, showing a 9.0% improvement postsurgery (Z = -15.292, P < 0.05). The health utility value difference in patients with echinococcosis ranged between -0.308 and 1.348, the VAS score difference ranged between -55 and 90. A total of 42.8% (366/856) patients had an increase in health utility value postsurgery, and 62.7% (537/856) of patients had an increase in VAS score postsurgery. The proportion of patients with reduction of difficulties in the five dimensions was 19.1% (818/4 280), unchanged was 76.5% (3 275/4 280), and those with stable overall health had higher health utility values (Z = -16.580, P < 0.05) and VAS scores (Z = -8.606, P < 0.05). The proportion of patients with increased difficulties was 4.4% (187/4 280), the average age of first operation in the group with decreased health utility value was higher than that in another group (Z = 4.393, P < 0.05). The average age of first operation in the group with decreased VAS score was higher than that in another group (Z = 3.154, P < 0.05). The patients’ health utility value (F = 12.957, Ptrend < 0.05) and VAS score (F = 10.808, Ptrend < 0.05) showed a trend of positive linear correlation with the extension of postsurgery time. Conclusion Surgical treatment could impact the quality of life for patients with echinococcosis.

Key words： Echinococcosis; EQ-5D-5L questionnaire; Surgical patients; Quality of life; Gansu Province

Cite this article

LIU Zehang , ZHANG Xiaojuan , YANG Guobing , LEI Jiaxi , LIU Baixue , WANG Ying , WANG Zhiyi , WANG Dong , FENG Yu , WANG Liying . Assessment of the quality of life of patients with echinococcosis in Gansu Province pre- and post-surgery based on the EQ-5D-5L questionnaire[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2024 , 42(2) : 182 -190 . DOI: 10.12140/j.issn.1000-7423.2024.02.008

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