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Research progress on combined use of drugs with albendazole in the treatment of echinococcosis

  • QIN Min ,
  • WANG Li-ying
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  • 1. National Institute of Parasitic Diseases, Chinese Centre for Disease Control and Prevention (Chinese Centre for Tropical Diseases Research); NHC Key Laboratory of Parasite and Vector Biology; WHO Collaborating Centre for Tropical Diseases; National Centre for International Research on Tropical Diseases, Shanghai 200025, China
    2. Tibet Center for Disease Control and Prevention; NHC Key Laboratory of Echinococcosis Prevention and Control, Lhasa 850000, China
    3. Doctorate School of Chemical and Biological Sciences for Health (CBS2); University of Montpellier,Montpellier 34395, France

Received date: 2022-01-19

  Revised date: 2022-01-25

  Online published: 2022-08-12

Supported by

National Natural Science Foundation of China(81703281);NHC Key Laboratory of Echinococcosis Prevention and Control, China(2021WZK1006)

Abstract

Echinococcosis is a parasitic disease that seriously affects the health and life safety of farmers and herdsmen. Albendazole is the primary clinical drug. However, the bioavailability of albendazole is low, requiring patients to increase the dosage and take medicine for a long time, producing certain adverse reactions and drug resistance. In order to improve the efficacy of albendazole and reduce the damage of drugs to the body, more and more studies pay attention to the combination of albendazole. This paper focuses on the advances progress of other drugs combined with albendazole in the treatment of echinococcosis to provide a reference for the further research and application of drug therapy in patients with echinococcosis.

Cite this article

QIN Min , WANG Li-ying . Research progress on combined use of drugs with albendazole in the treatment of echinococcosis[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2022 , 40(5) : 647 -655 . DOI: 10.12140/j.issn.1000-7423.2022.05.013

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