CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES >
The toxicological and pharmacological effects of parasite-derived components on the host
Received date: 2022-05-09
Revised date: 2022-07-05
Online published: 2022-08-09
Supported by
Natural Science Foundation of China(81971965);Natural Science Foundation of Jiangsu Province(BK20211586);Qing Lan Project of Jiangsu Province(KY101R202127);Medical Scientific Research Project of Jiangsu Provincial Health Commission(Z2021004)
In recent years, a new translational medicine proposition, the toxicological and pharmacological effects of parasite-derived components on the host, has received extensive attention. Therefore, an in-depth understanding of parasite-derived molecules’ toxicological and pharmacological effects from the perspective of infection immunology can deepen our understanding of the pathogenesis of parasitic diseases but also facilitate research and development based on the concept of translational medicine. The transformational application value of parasite-derived molecules has become and will continue to be one of the most fantastic research tasks in the field of parasite research. This review focuses on recent advances in the pharmacological effects of zoonotic parasites and their derived components in inducing and regulating host immunometabolism-related diseases, and explores their potential mechanisms.
XU Zhi-peng , JI Min-jun , WU Guan-ling . The toxicological and pharmacological effects of parasite-derived components on the host[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2022 , 40(5) : 561 -571 . DOI: 10.12140/j.issn.1000-7423.2022.05.001
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