CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES >

2022 , Vol. 40 >Issue 2: 140 - 145

DOI: https://doi.org/10.12140/j.issn.1000-7423.2022.02.002

SPECIAL REPORTS

New strategies for malaria control: using mosquito symbiotic bacteria to block malaria transmission

  • JIANG Yong-mao ,
  • GAO Han ,
  • WANG Si-bao
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  • CAS Key Laboratory of Insect Developmental and Evolutionary Biology, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China

Received date: 2021-12-27

  Revised date: 2022-02-21

  Online published: 2022-03-31

Supported by

National Natural Science Foundation of China(31830086);National Natural Science Foundation of China(32021001)

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Abstract

Malaria is a mosquito borne parasitic disease caused by Plasmodium infection. In the absence of highly effective vaccines, controlling malaria mainly relies on mosquito-controlling insecticides and antimalarial drugs. However, increased resistance to insecticides among mosquitoes and the emergence and spread of antimalarial drug-resistant parasites have become significant challenges in the fight against malaria. In recent years, global progress toward malaria prevention and control has remained stagnant, and new strategies to control malaria are urgently needed. Symbiotic control is a new strategy that uses mosquito gut symbiotic microorganisms to control vector mosquitoes or reduce vector competence. This strategy has made remarkable progress in recent years. Here, the advances in the development and research of this technology are reviewed, and the challenges in the application of symbiotic control of malaria are discussed.

Key words： Malaria; Anopheles; Plasmodium; Symbiotic bacteria; Symbiotic control

Cite this article

JIANG Yong-mao , GAO Han , WANG Si-bao . New strategies for malaria control: using mosquito symbiotic bacteria to block malaria transmission[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2022 , 40(2) : 140 -145 . DOI: 10.12140/j.issn.1000-7423.2022.02.002

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