CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES >

2021 , Vol. 39 >Issue 6: 725 - 730

DOI: https://doi.org/10.12140/j.issn.1000-7423.2021.06.002

INVITED REVIEWS

Research progress on proteomics in Schistosoma japonicum

  • Yang HONG ,
  • Jiao-jiao LIN
Expand
  • National Reference Laboratory for Animal Schistosomiasis, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Key Laboratory of Animal Parasitology of Ministry of Agriculture and Rural Affairs, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China

Received date: 2021-11-17

  Revised date: 2021-12-01

  Online published: 2021-12-22

Supported by

National Key Research and Development Program of China(2017YFD0501306)

Fold

Abstract

Protein is the major exhibiter and executer of gene function. In recent years, the proteomics studies of Schistosoma japonicum has attracted the attention of researchers and made some progress. This paper reviews the research progress in proteomics of S. japonicum to provide information of referential value for elaborating the mechanism of schistosome growth and development as well as screening potential diagnostic antigens, vaccine candidate molecules and new therapeutic drug targets.

Key words： Schistosoma japonicum; Proteomics; Mechanism of growth and development

Cite this article

Yang HONG , Jiao-jiao LIN . Research progress on proteomics in Schistosoma japonicum[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2021 , 39(6) : 725 -730 . DOI: 10.12140/j.issn.1000-7423.2021.06.002

References

[1] Zhao XY, Yao LX, Sun AG, et al. Analysis of differentially expressed partial protein of schistosomulum of Schistosoma japonicum using mass spectrometry[J]. Vet Sci China, 2007, 37(1): 1-6. (in Chinese)
[1] (赵晓宇, 姚利晓, 孙安国, 等. 日本血吸虫童虫部分差异表达蛋白的质谱分析[J]. 中国兽医科学, 2007, 37(1): 1-6.)
[2] Liu M, Ju C, Du XF, et al. Proteomic analysis on cercariae and schistosomula in reference to potential proteases involved in host invasion of Schistosoma japonicum larvae[J]. J Proteome Res, 2015, 14(11): 4623-4634.
[3] Hong Y, Sun AG, Zhang M, et al. Proteomics analysis of differentially expressed proteins in schistosomula and adult worms of Schistosoma japonicum[J]. Acta Trop, 2013, 126(1): 1-10.
[4] Liu F, Cui SJ, Hu W, et al. Excretory/secretory proteome of the adult developmental stage of human blood fluke, Schistosoma japonicum[J]. Mol Cell Proteomics, 2009, 8(6): 1236-1251.
[5] Cheng GF, Lin JJ, Feng XG, et al. Proteomic analysis of differentially expressed proteins between the male and female worm of Schistosoma japonicum after pairing[J]. Proteomics, 2005, 5(2): 511-521.
[6] Qu GL, Tao YH, Li HJ, et al. Proteomic analysis of different isolates of Schistosoma japonicum in mainland of China[J]. Chin J Schisto Control, 2010, 22(4): 315-319. (in Chinese)
[6] (曲国立, 陶永辉, 李洪军, 等. 中国大陆日本血吸虫地理株间成虫蛋白质组分的差异[J]. 中国血吸虫病防治杂志, 2010, 22(4): 315-319.)
[7] Wu ZD, Fung MC, Xu J, et al. Soluble proteins analysis of male and female Schistosoma japonicum by two-dimensional gelelectrophoresis[J]. J Trop Med, 2001, 1(2): 120-122. (in Chinese)
[7] (吴忠道, 冯明钊, 徐劲, 等. 日本血吸虫雌雄成虫可溶性蛋白组分的双向电泳分析[J]. 热带医学杂志, 2001, 1(2): 120-122.)
[8] Li XC, Qiao HB, Qin FL, et al. Comparative analysis of iTRAQ-based proteome profiles of Schistosoma japonicum female worms coming from single-sex infections and bisexual infections[J]. J Proteomics, 2020, 213: 103597.
[9] He YX, Salafsky B, Ramaswamy K. Host: parasite relationships of Schistosoma japonicum in mammalian hosts[J]. Trends Parasitol, 2001, 17(7): 320-324.
[10] Zhai Q, Fu ZQ, Hong Y, et al. iTRAQ-based comparative proteomic analysis of adult Schistosoma japonicum from water buffalo and yellow cattle[J]. Front Microbiol, 2018, 9: 99.
[11] Hong Y, Peng JB, Jiang WB, et al. Proteomic analysis of Schistosoma japonicum schistosomulum proteins that are differentially expressed among hosts differing in their susceptibility to the infection[J]. Mol Cell Proteomics, 2011, 10(8): M110.006098.
[12] Liu F, Lu J, Hu W, et al. New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum[J]. PLoS Pathog, 2006, 2(4): e29.
[13] Zhang M, Hong Y, Han YH, et al. Proteomic analysis of tegument-exposed proteins of female and male Schistosoma japonicum worms[J]. J Proteome Res, 2013, 12(11): 5260-5270.
[14] Cao XD, Fu ZQ, Zhang M, et al. iTRAQ-based comparative proteomic analysis of excretory-secretory proteins of schistosomula and adult worms of Schistosoma japonicum[J]. J Proteomics, 2016, 138: 30-39.
[15] Yu CX, Zhao F, Yin XR, et al. Proteomic analysis of vomit and excretory/secretory products of Schistosoma japonicum[J]. Chin J Schisto Control, 2010, 22(4): 304-309. (in Chinese)
[15] (余传信, 赵飞, 殷旭仁, 等. 日本血吸虫成虫呕吐和排泄分泌物的蛋白质组学分析[J]. 中国血吸虫病防治杂志, 2010, 22(4): 304-309.)
[16] Carson JP, Robinson MW, Hsieh MH, et al. A comparative proteomics analysis of the egg secretions of three major schistosome species[J]. Mol Biochem Parasitol, 2020, 240: 111322.
[17] De Marco Verissimo C, Potriquet J, You H, et al. Qualitative and quantitative proteomic analyses of Schistosoma japonicum eggs and egg-derived secretory-excretory proteins[J]. Parasit Vectors, 2019, 12(1): 173.
[18] Cao XD. Analysis of excretory-secretory proteins of Schistosoma japonicum[D]. Beijing: Chinese Academy of Agricultural Sciences Dissertation, 2016: 66-68. (in Chinese)
[18] (曹晓丹. 日本血吸虫排泄分泌蛋白的研究[D]. 北京: 中国农业科学院, 2016: 66-68.)
[19] Sun XL, Zhang LB, Wang JX, et al. Schistosoma japonicum protein SjP40 inhibits TGF-beta1-induced activation of hepatic stellate cells[J]. Parasitol Res, 2015, 114(11): 4251-4257.
[20] Liao Q, Yuan XY, Xiao H, et al. Identifying Schistosoma japonicum excretory/secretory proteins and their interactions with host immune system[J]. PLoS One, 2011, 6(8): e23786.
[21] Luo R, Zhou CJ, Lin JJ, et al. Identification of in vivo protein phosphorylation sites in human pathogen Schistosoma japonicum by a phosphoproteomic approach[J]. J Proteomics, 2012, 75(3): 868-877.
[22] Cheng GF, Luo R, Hu C, et al. TiO2-based phosphoproteomic analysis of schistosomes: Characterization of phosphorylated proteins in the different stages and sex of Schistosoma japonicum[J]. J Proteome Res, 2013, 12(2): 729-742.
[23] Hong Y, Cao XD, Han Q, et al. Proteome-wide analysis of lysine acetylation in adult Schistosoma japonicum worm[J]. J Proteom, 2016, 148: 202-212.
[24] Li Q, Zhao N, Liu M, et al. Comparative analysis of proteome-wide lysine acetylation in juvenile and adult Schistosoma japonicum[J]. Front Microbiol, 2017, 8: 2248.
[25] Zhong ZR, Zhou HB, Li XY, et al. Serological proteome-oriented screening and application of antigens for the diagnosis of schistosomiasis japonica[J]. Acta Trop, 2010, 116(1): 1-8.
[26] Zhang M, Fu ZQ, Li CJ, et al. Screening diagnostic candidates for schistosomiasis from tegument proteins of adult Schistosoma japonicum using an immunoproteomic approach[J]. PLoS Negl Trop Dis, 2015, 9(2): e0003454.
[27] Xu XD, Zhang YB, Lin DD, et al. Serodiagnosis of Schistosoma japonicum infection: genome-wide identification of a protein marker, and assessment of its diagnostic validity in a field study in China[J]. Lancet Infect Dis, 2014, 14(6): 489-497.
[28] Siddiqui AA, Ahmad G, Damian RT, et al. Experimental vaccines in animal models for schistosomiasis[J]. Parasitol Res, 2008, 102(5): 825-833.
[29] Hong Y, Zhang M, Yang JM, et al. Immunoproteomic analysis of Schistosoma japonicum schistosomulum proteins recognized by immunoglobulin G in the sera of susceptible and non-susceptible hosts[J]. J Proteomics, 2015, 124: 25-38.
[30] Zhai Q. Comparative proteomic and immunoproteomic analysis of Schistosoma japonicum from water buffalo and yellow cattle[D] Guangzhou: South China Agricultureal University, 2018: 72-76. (in Chinese)
[30] (翟颀. 水牛和黄牛来源日本血吸虫蛋白质组和免疫蛋白质组比较研究[D]. 广州: 华南农业大学, 2018: 72-76.)
[31] Yang LL, Lv ZY, Hu SM, et al. Schistosoma japonicum: proteomics analysis of differentially expressed proteins from ultraviolet-attenuated cercariae compared to normal cercariae[J]. Parasitol Res, 2009, 105(1): 237-248.
[32] Wu HW, Park S, Pond-Tor S, et al. Whole-proteome differential screening identifies novel vaccine candidates for schistosomiasis japonica[J]. J Infect Dis, 2021, 223(7): 1265-1274.
[33] Ismail M, Metwally F, Farghaly A, et al. Characterization of isolates of Schistosoma mansoni from Egyptian villagers that tolerate high doses of praziquantel[J]. Am J Trop Med Hyg, 1996, 55(2): 214-218.
[34] Zhang L, Liu F, Cui SJ, et al. Proteomic analysis of adult Schistosoma japonicum treated with praziquantel[J]. Chin J Parasitol Parasit Dis, 2008, 26(4): 258-262. (in Chinese)
[34] (张玲, 刘峰, 崔书健, 等. 吡喹酮处理日本血吸虫成虫蛋白质组学分析[J]. 中国寄生虫学与寄生虫病杂志, 2008, 26(4): 258-262.)
[35] Kong QM, Tong QB, Lou D, et al. Quantitative proteomic analyses of Schistosoma japonicum in response to artesunate[J]. Mol Biosyst, 2015, 11(5): 1400-1409.
Options
Outlines

/

〈 〉