CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES >

2021 , Vol. 39 >Issue 3: 386 - 392

DOI: https://doi.org/10.12140/j.issn.1000-7423.2021.03.015

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Solid organ transplantation and toxoplasmosis

  • Zi-yun HUANG ,
  • Fang-li LV
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  • 1 Department of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China
    2 Key Laboratory of Tropical Disease of Ministry of Education, Sun Yat-sen University, Guangzhou 510080, China
    3 Provincial Engineering Technology Research Center for Biological Vector Control, Guangzhou 510080, China

Received date: 2020-09-21

  Revised date: 2020-11-19

  Online published: 2021-07-05

Supported by

National Natural Science Foundation of China(81971955);Natural Science Foundation of Guangdong Province(2019A1515011667);Natural Science Foundation of Guangdong Province(2021A1515012115);Open Project of Key Laboratory of Tropical Disease Control of Ministry of Education, Sun Yat-sen University(2020ZX02);Undergraduate Teaching Quality Engineering Project of Sun Yat-sen University（SYSU Undergraduate Education [2021]93）;Undergraduate Teaching Quality Engineering Project of Sun Yat-sen University（SYSU Undergraduate Education [2020]72）

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Abstract

Toxoplasma gondii infection in immunocompetent people is often asymptomatic, but may lead to severe clinical symptoms in immunocompromised patients, even with fatal consequences. Due to the diversity of solid organ transplants, the degrees of immunosuppression, and the relatively low incidence of toxoplasmosis among organ transplant recipients, the clinical risk of T. gondii infection in organ transplant patients remains poorly understood. Therefore, this paper reviews the clinical manifestations, pathogenesis, diagnosis, prevention, and treatment of toxoplasmosis in solid organ transplant recipients, in order to provide reference for clinical diagnosis and treatment of toxoplasmosis after solid organ transplantation.

Key words： Toxoplasma gondii; Solid organ transplantation; Pathogenesis; Diagnosis; Prevention; Treatment

Cite this article

Zi-yun HUANG , Fang-li LV . Solid organ transplantation and toxoplasmosis[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2021 , 39(3) : 386 -392 . DOI: 10.12140/j.issn.1000-7423.2021.03.015

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