CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES >
Analysis of clinical features of echinococcosis cases
Received date: 2020-05-22
Revised date: 2020-08-13
Online published: 2021-03-10
Supported by
2016 Health and Family Planning Guiding Subject of Qinghai Provincial Health and Family Planning Commission(2016-wjzdx-11)
Objective To analyze the clinical features and treatment of echinococcosis inpatients in Qinghai Province, in order to provide scientific basis for improvement of diagnosis and treatment of echinococcosis. Methods Demographic and clinical information of 949 echinococcosis inpatients in Qinghai Provincial People’s Hospital during January 2016 and June 2019 were collected and entered in database in duplicates by using the EpiData software 3.02. Univariate analysis was performed for the two types of echinococcosis, using hydatid disease as the dependent variable. Logistic regression model was constructed based on the univariate analysis results, in order to analyze factors influencing the treatment outcome of echinococcosis. Data were analyzed with the SPSS 17.0 software. Results Clinical information of 949 echinococcosis cases was collected, including 756 cystic echinococcosis (CE) cases comprising 350 males and 406 females, and 193 alveolar echinococcosis (AE) cases comprising 90 males and 103 females. There were 524 Tibetan CE cases and 141 Tibetan AE cases. The cases were mainly distributed in farmers and herdsmen, including 604 CE cases and 157 AE cases. Most of the cases were illiterate, including 596 CE cases and 147 AE cases. CE cases were mainly distributed in Yushu Prefecture (209 cases) and AE mainly in Guoluo Prefecture (93 cases). In addition, 548 CE cases and 141 AE cases had clinical symptoms of abdominal discomfort, while 663 CE cases and 142 AE cases had Child-Pugh stage A of liver functions. Ultrasound imaging classification revealed 227 cases of the CE2 type and 302 cases of the CE4 type, and the predominance of AE1 type among the AE cases. Moreover, 19.8% CE cases and 19.2% AE cases had complications; 409 CE cases and 83 AE cases received surgery. The univariate analysis of CE showed that gender, age, cyst size, ultrasonic image classification, the occurrence of complications and prognosis of surgery (P < 0.01) were different between groups. The univariate analysis of AE showed that the Child-Pugh score (P < 0.05) and prognosis of surgery (P < 0.01) were different between groups. Logistic regression results showed that the main factors influencing the cure of CE were gender (P < 0.05), cyst size (P < 0.05) and whether or not receiving surgery (P < 0.01), while surgery (P < 0.01) was the main factor influencing the cure of AE. Conclusion The clinical data of the two types of echinococosis in Qinghai Province suggest that surgery is an effective way to improve the cure rate of AE and CE.
Ling-hong ZHU , Lu-min ZHU , Bo WANG , Zhi-yong YANG , Jing-ni ZHANG , Li JI , Qi-gang CAI , Xiu-min HAN . Analysis of clinical features of echinococcosis cases[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2021 , 39(1) : 61 -68 . DOI: 10.12140/j.issn.1000-7423.2021.01.009
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