CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES >

2020 , Vol. 38 >Issue 3: 390 - 394

DOI: https://doi.org/10.12140/j.issn.1000-7423.2020.03.021

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Advances in research on Nod-like receptor protein 3 inflammasome in parasitic diseases

  • Cai-song CHEN ,
  • Yao-gang ZHANG ,
  • Zhi-xin WANG ,
  • Hai-ning FAN
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  • 1 Affiliated Hospital of Qinghai University, Xining 810001, China
    2 Qinghai Province Research Key Laboratory for Echinococcosis, Xining 810001, China

Received date: 2019-08-26

  Online published: 2020-07-07

Supported by

National Major Research and Development Project of Precision Medicine Research(2017YFC0909900);Qinghai Province Science and Technology Department Programme(2019-SF-131);Qinghai Province Health and Family Planning Commission Programme(2016-wjzd-04)

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Abstract

Inflammatory corpuscles are receptors of the innate immune system and participate in the stress responses against pathogenic organisms after activated. This review summarizes the basic structure and functions of Nod-like receptor protein 3 (NLRP3) inflammasome as well as the related researches on malaria, amoebic disease, trypanosomiasis, leishmaniasis, schistosomiasis, and vaginal trichomoniasis, aiming to analyze the role and mechanism of NLRP3 inflammasome in parasitic diseases and provide ideas for better interventions and treatment.

Key words： Parasitic disease; Nod-like receptor protein 3 inflammasome; Inflammation; Immune response

Cite this article

Cai-song CHEN , Yao-gang ZHANG , Zhi-xin WANG , Hai-ning FAN . Advances in research on Nod-like receptor protein 3 inflammasome in parasitic diseases[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2020 , 38(3) : 390 -394 . DOI: 10.12140/j.issn.1000-7423.2020.03.021

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