Advances in ubiquitination modification of apicomplexa protozoans

doi:10.12140/j.issn.1000-7423.2019.02.019

Abstract

Abstract:

Apicomplexa phylum is a family of specific intracellular parasitic protozoans that undergo complex life cycles involving multiple developmental stages with distinct morphologies. Post-translational modification (PTM) occur throughout the complex life cycle of apicomplexan to regulate cellular processes and play roles in all aspects of cytobiology. Ubiquitination is a common modification in PTM. Protein ubiquitination plays a key role in protein turnover, cell signaling and intracellular transport. In this review, we summarize the ubiquitination modification of important organelles in apicomplexa protozoans to better understand the effect of ubiquitination on the cell cycle and functions of apicomplexan.

Key words: Apicomplexa phylum, Post-translational modification, Ubiquitination modification, Cell cycle

CLC Number:

R531

Hao-rui LI, Hai-bin HUANG, Gui-lian YANG. Advances in ubiquitination modification of apicomplexa protozoans[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2019, 37(2): 223-227.

References 46

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