Dendritic Cells and Th2 Response Induced by Schistosome Infection

›› 2008, Vol. 26 ›› Issue (1): 14-66.

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Dendritic Cells and Th2 Response Induced by Schistosome Infection

ZANG Wei,SHEN Yu-juan,CAO Jian-ping*

National Institute of Parasitic Diseases，Chinese Center for Disease Control and Prevention；Laboratory of Parasite and Vector Biology，MOH，China; WHO Collaborating Centre of Malaria，Schistosomiasis and Filariasis，Shanghai 200025，China

Received:1900-01-01 Revised:1900-01-01 Online:2008-02-28 Published:2008-02-28
Contact: CAO Jian-ping

Abstract

Abstract: Dendritic cells act as the major antigen presenting cells in the body and play a central role in intri-guing the adaptive immune response. Protective immunity against schistosome and immuno-pathological response in host caused by eggs are both closely associated with Th2 response. Further understanding on immune mechanism will contribute to the development of vaccines against schistosome infection， as well as the relief of the pathological lesion in schistosomiasis. This article discusses the central role of dendritic cells in the mechanism of Th2 response induced by schistosome （including eggs）.

Key words: Dendritic cells, Th2 response, Schistosome

ZANGWei;SHENYu-juan;CAOJian-ping*. Dendritic Cells and Th2 Response Induced by Schistosome Infection[J]. , 2008, 26(1): 14-66.

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Dendritic Cells and Th2 Response Induced by Schistosome Infection

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