Epidemiological analysis on the imported cases of schistosomiasis in Zhejiang Province during 1996-2017

Abstract

Abstract:

Objective To analyze the dynamic change and the factors that effect on the imported schistosomiasis case since the disease transmission blocking criteria have been met in Zhejiang Province in 1995. Methods Data for the imported case of schistosomiasis and snail investigation in Zhejiang Province from 1996 to 2017 were collected and analyzed retrospectively for the case distribution, diagnosis, treatment and for snail ridden area. Results Totally 245 cases of imported schistosomiasis were reported in 30 counties in Zhejiang Province from 1996-2017, including 41 cases of acute Schistosoma japonicum infection. Among them, 241 cases were imported from other provinces in China, mainly from neighboring Jiangxi (37.3%, 90/241） and Anhui (29.9%, 72/241). Four of them were imported from Nigeria in Africa including 3 cases of S. haematobium and 1 case of S. mansoni infections. The number of imported cases was increased in the years before 2005 with up to 40 cases in 2005, and then gardually to decreased. More cases were reported in the second half of each year (80.8%, 198/245). The imported cases were reported in total 30 counties (cities, district) in the province, most of them (230) were reported in 25 counties in the 8 historially endemic cities, and Ningbo had the largest number of imported cases (55.9%, 137/245) followed by Hangzhou (18.4%, 45/245) and Quzhou (6.9%, 17/245). Among the total 245 cases, 180 were males and 65 females. More cases were found in those with low education (29.8% with primary school and 49.4% with junior high school) and with blue collar occupations (farmers 42.0%, workers 23.3%) and in students (14.7%). Of the 241 cases imported from other provinces, 85.1% (205/241) cases were infected from uncontrolled or re-emerging endemic areas. Most cases were infected by the contact with contaminated water during swimming (37.1%) or agricultural practices (36.3%). More cases were identified by active monitor of local disease control authorities (51.4%, 126/245) than in clinics (48.6%, 119/245). 59.6% of the cases seeked for medication at the first time at the local county hospitals and 49.6% of them（59/119）was misdiagnosed. Snail was found in 30 formally endemic counties with a total area of 1 739.0 hm². Conclusion The total 245 cases of imported schistosomiasis have been reported in Zhejiang Province through active monitoring and passive reporting system from 1996 to 2017. The number of cases has decreased since 2005. The main sources of the imported cases are from the uncontrolled or re-emerging areas of schistosomiasis in the country.

Key words: Schistosomiasis, Imported case, Endemic, Epidemiology, Zhejiang Province

CLC Number:

R532.21

Jian-feng ZHANG, Xiao-lan YAN, Li-yong WEN, Xiao ZHANG, Li-ling YU, Hai-juan DU, Ming-jin YANG. Epidemiological analysis on the imported cases of schistosomiasis in Zhejiang Province during 1996-2017[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2018, 36(6): 586-592.

Figures/Tables 5

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References 21

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年份Year	浙江省输入性病例数No. of imported cases in Zhejiang Province					全国血吸虫病病例数/万 No. of cases with schistosomiasis in China/10 thousand
年份Year	慢性日本血吸虫病病例数 No. of cases with chronic schistosomiasis japonica	急性日本血吸虫病病例数 No. of cases with acute schistosomiasis japonica	曼氏血吸虫病病例数 No. of cases with schistosomiasis mansoni	埃及血吸虫病病例数 No. of cases with schistosomiasis haematobia	合计 Total
1996	0	0	0	0	0	81.0
1997	0	1	0	0	1	79.1
1998	1	1	0	0	2	76.2
1999	0	3	0	0	3	75.7
2000	0	4	0	0	4	69.5
2001	2	1	0	0	3	82.1
2002	1	8	0	0	9	81.0
2003	3	3	0	0	6	84.3
2004	9	8	0	0	17	84.3
2005	37	3	0	0	40	79.9
2006	31	1	0	0	32	67.1
2007	23	1	0	0	24	51.6
2008	11	2	0	0	13	41.3
2009	19	1	0	0	20	36.6
2010	9	0	0	0	9	32.6
2011	7	2	0	0	9	28.7
2012	6	1	0	0	7	24.1
2013	13	0	1	0	14	18.5
2014	9	0	0	0	9	11.6
2015	7	0	0	1	8	7.7
2016	7	0	0	2	9	5.4
2017	5	1	0	0	6	3.8
合计Total	200	41	1	3	245	1 121.9

特征Feature	急性日本血吸虫病病例 No. of cases with acute schistosomiasis japonica	慢性日本血吸虫病病例 No. of cases with chronic schistosomiasis japonica	曼氏血吸虫病病例 No. of cases with schistosomiasis mansoni	埃及血吸虫病病例 No. of cases with schistosomiasis haematobia	构成比/% Proportion/%
文化程度Education
文盲llliteracy	4	6	0	0	4.1
小学Primary school	20	53	0	0	29.8
初中Junior high school	17	100	1	3	49.4
高中Senior high school	0	27	0	0	11.0
大专及以上College and above	0	14	0	0	5.7
职业Occupation
农民Farmer	11	92	0	0	42.0
工人Worker	2	52	0	3	23.3
学生Student	23	13	0	0	14.7
商业服务者Business Services	0	21	1	0	9.0
渔船民Fisherman and boatman	5	15	0	0	8.2
教师及干部 Teacher or government employee	0	7	0	0	2.8
感染方式Way of infection
游泳戏水 Swimming and water-playing	23	65	0	3	37.1
农业生产Agricultural production	11	77	1	0	36.3
渔业生产Fishery production	6	26	0	0	13.1
生活用水Daily life activity	0	30	0	0	12.2
未知Unknown	1	2	0	0	1.3
既往史Previous history
无治疗史Without treatment history	37	131	1	3	70.2
有治疗史Treatment history	4	69	0	0	29.8

初诊单位 First visited medical units	病例数 No. of cases	构成比/% Proportion/%	其中被动报病数 No. of cases of passive surveillance	误诊人数 No. of cases of misdiagnosis	误诊率/% Misdiagnosis rate/%
省级Provincial-level	10	4.1	10	4	40.0
市级Prefecture-level	34	13.9	28	12	42.9
县级County-level	146	59.6	44	16	36.4
乡（镇）级Township	55	22.4	37	27	73.0
合计Total	245	100	119	59	49.6