›› 1985, Vol. 3 ›› Issue (4): 269-271.

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THE EMBRYOTOXICITY OF BROMOACETAMIDE IN RATS

  

  • Online:1985-11-30 Published:2017-01-12

Abstract: When pregnant albino rats were administered orally with a newly developed molluscicide bromoacetamide at the dosage of≥24.8 mg/kg/d (≥1/5 LD50) for 12 consecutive days, starting from the 6th day of gestation, decreased live foetuses and some external abnormalities were observed. By comparison, an other molluscicide sodium pentaehlorophenate, a known teratogen, at the dosage of ≥25.1 mg/kg/d (≥1/9 LD50) produced much more pronounced skeletal and external dysmorphosis.