Abstract: This article compares the routine methods used in circumoval precipitin testa with PVC-COP using PVC membrane slide coated with egg antigen.By applying the above method to 82 parasitologically confirmed cases, we found that 80 of them showed positive reaction which means a positive rate of 97.6%. When applied to 361 healthy persons, the false positive rate was found to be 1.79%. By com-paring routine COP method with PVC-COP on 694 sera from different endemic areas, no statistical difference was found between the positive rate and the average circumoval precipitin rate (P0.05).On the whole PVC-COP is sensitive, specific and takes less time, material and labor, the slides can be easily carried or mailed, thus proved to be practical in field and epidemiological surveys.