›› 2013, Vol. 31 ›› Issue (5): 15-400-405.
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ZHOU Chao-qun1，WANG Yong-yang1，WANG Xue-long 2 *
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Published:
Abstract: Schistosomiasis hepatic fibrosis results from excessive deposition of extracellular matrix components which are produced from the activated hepatic stellate cells in liver. Cytokine network disorder is the essential cause of the development of schistosomiasis liver fibrosis. Transforming growth factor β1（TGF-β1） and interleukin 13 （IL-13） promote fibrosis through hepatic stellate cell membrane-specific receptor. This paper reviews the effects of TGF-β1 type Ⅱ（TGF-β1 RⅡ） receptor and IL-13 receptor α2（IL-13 Rα2）on hepatic fibrosis．
Key words: TGF-&beta, 1 RⅡ；IL-13 R&alpha, 2；Hepatic fibrosis；Schistosomiasis
ZHOU Chao-qun1，WANG Yong-yang1，WANG Xue-long 2 *. The Role of Transforming Growth Factor β1 RⅡ and Interleukin 13 Rα2 in Schistosomiasis-induced Hepatic Fibrosis[J]. , 2013, 31(5): 15-400-405.
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https://www.jsczz.cn/EN/Y2013/V31/I5/15
