Abstract: Data were collected from chronic lymphatic filariasis patients and the public in Yuhang District of Hangzhou. Health status was assessed by using EuroQol （EQ）-5D. A total of 600 questionnaires were sent and 550 （91.7%） returned （276 chronic lymphatic filariasis patients and 274 members of the public）. The EQ-5D index score for patients with chronic lymphatic filariasis （0.770±0.128） were lower than the general public （0.872±0.073）. In contrast to the public（6.6%, 5.8%, 12.0%, 20.4%, and 10.6%）, patients reported more problems with their mobility（43.8%）, self-care（22.5%）, daily activities （44.9%）, anxiety/depression （47.8%）, and pain/discomfort （29.0%） （P<0.01）. Strength of association were 6.67, 3.86, 3.74, 2.73, and 2.34, respectively. These results indicated that chronic lymphatic filariasis shows an impact on patients′ health-related quality of life. It particularly causes great problems in the dimensions of mobility, self-care, and daily activities.

Key words: Chronic lymphatic filariasis, Patient, Life quality