›› 2009, Vol. 27 ›› Issue (6): 10-502.

• 实验研究 • Previous Articles     Next Articles

Field Evaluation of Gold-Immunochromatographic Assay for Diagnosis of Vivax Malaria

WANG Jun-yun1,WANG Jian-jun2,SHI Feng1,XU Xian2,YANG Yue-tao1,GAO Chun-hua1,ZHENG Xiang1,GE Jun3,TANG Lin-hua1   

  1. 1 National Institute of Parasitic Diseases，Chinese Center for Disease Control and Prevention，WHO Collaborating Centre for Malaria，Schistosomiasis and Filariasis，Shanghai 200025，China；2 Anhui Provincial Center for Disease Control and Prevention，Hefei 230061，China；3 Center for Disease Control and Prevention of Mengcheng County，Mengcheng 233500，China
  • Received:1900-01-01 Revised:1900-01-01 Online:2009-12-30 Published:2009-12-30

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Abstract: Objective To evaluate a gold-immunochromatographic assay（GICA） for malaria diagnosis in an endemic area of vivax malaria. Methods Blood samples were collected from febrile patients in 5 township-hospitals of Mengcheng County, Anhui Province, between September and October 2008. The samples were examined by GICA and microscopy under double blind condition and the results were compared. Results Among 292 blood samples, 181 were found P. vivax-positive by microscopy, and 163 were positive by GICA. Altogether, the coincidence of the two methods stood for 92.8%（271/292）, including 108 negatives and 163 positives. 21 samples with discrepancy covered 18 microscopy positive but GICA negative, 3 microscopy negative but GICA positive. The GICA positive rate in patients with a parasitaemia of ＞1 000 parasites/μl，100-1 000 parasites/μl，and ＜100 parasites/μl was 93.5%（115/123）、86.0%（43/50）, and 62.5%（5/8）, respectively. Conclusion GICA is a useful diagnosis method for endemic area of vivax malaria.

Key words: Gold immunochromatographic assay, Diagnosis, Plasmodium vivax, Malaria