Diagnostic and therapeutic analysis of a case of cysticercosis involving the nervous system and subcutaneous muscles

CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES ›› 2026, Vol. 44 ›› Issue (2): 305-307.doi: 10.12140/j.issn.1000-7423.2026.02.023

• CASE REPORT • Previous Articles    

Diagnostic and therapeutic analysis of a case of cysticercosis involving the nervous system and subcutaneous muscles

ZHANG Yan1,2(), WEN Yang1, ZHU Yu1,*()()   

  1. 1 Department of Pediatric Infectious Diseases, West China Second Hospital, Sichuan University; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu 610041, Sichuan, China
    2 Department of Pediatrics, Chengdu BOE Hospital, Chengdu 610219, Sichuan, China
  • Received:2025-11-17 Revised:2026-01-09 Online:2026-04-30 Published:2026-04-13
  • Supported by:
    2022 National Project for Clinical Key Specialty Development (Sichuan Health Commission Medical Administration Letter [2023] No. 87)

Abstract:

A 8-year-old male Tibetan child was admitted to the West China Second Hospital of Sichuan University on October 25, 2024, due to intermittent fever, headache and vomiting. The patient had long resided in Mangkang County, Changdu City, Xizang Autonomous Region, with cattle and sheep raised in his family, and he had a history of consuming raw beef and mutton. Physical examination revealed a palpable mass near the elbow joint on the medial side of the left upper arm, measuring 2 cm × 1.5 cm with no significant tenderness. Serological tests showed positive IgG antibodies against Echinococcus, and liver function tests indicated alanine aminotransferase at 59 U/L and aspartate aminotransferase at 58 U/L. Respiratory multiplex pathogen nucleic acid assay tested positive for rhinovirus. Tapeworm eggs were identified in stool samples on October 29, October 30, and November 6. Head MRI scans (plain scan + contrast enhancement) displayed multiple space-occupying lesions in the bilateral cerebral hemispheres, presenting as circle-like long T1 and long T2 signal shadows, and superficial ultrasound of the left upper arm showed a cystic-solid mass within the muscular layer of biceps brachii. On November 1, 2024, a subcutaneous and intramuscular nodule resection was performed in the left upper arm, and pathological biopsy identified parasites in the muscle and fibrous tissues, which confirmed the diagnosis of neurocysticercosis, subcutaneous, and muscular cysticercosis. The child was given anti-parasitic treatment with albendazole [15 mg/(kg·d)] and praziquantel [(50 mg/(kg·d)] for 10 days, followed by anti-inflammatory therapy with dexamethasone. He had improvements and was then discharged from hospital. After discontinuation for 3 days, drug administration was resumed for another 10 days. Follow-up calls at 3 and 6 months post-discharge showed no significant abnormalities.

Key words: Neurocysticercosis, Diagnosis, Treatment, Albendazole, Praziquantel

CLC Number: