Research progress on host cell immunity in Fasciola hepatica infection

doi:10.12140/j.issn.1000-7423.2021.01.016

Abstract

Abstract:

Fascioliasis hepatica is a devastating zoonotic disease. Fasciola hepatica mainly infects ruminants and mammals including humans. Fascioliasis hepatica has become a public health problem that poses severe threats to human health and economic development. Currently, the treatment of fascioliasis hepatica is challenged by limited medication choice and unsatisfactory curative effect. Extensive studies have shown that F. hepatica infection is regulated by the immune response of the host. In this review, we summarize the pathogenesis of fascioliasis hepatica, several cellular immune responses induced by F. hepatica and related research progress, in order to provide information for the clinical treatment of fascioliasis hepatica.

Key words: Fasciola hepatica, Pathogenesis, Cellular immunity

CLC Number:

R532.29

ZHANG Bao-yue, SONG Zheng-yi. Research progress on host cell immunity in Fasciola hepatica infection[J]. CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES, 2021, 39(1): 107-112.

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