›› 1999, Vol. 17 ›› Issue (1): 7-27.

• 论著 • Previous Articles     Next Articles

OBSERVATION ON THE CL INICAL SYM PTOM S ANDSPOROCYST EXCRETION IN HUMAN VOLUNTEERSEXPERIM ENTALLY INFECTED W ITH SARCOCYSTIS HOM IN IS

CHEN Xinwen1, 　ZUO Yangxian1, 　ZUO Weiwei2   

  1. 1　Biology Department of Yunnan University , Kunming 6500912　Department of Laboratory , First Affiliated Hospital of Kunming Medical College, Kunming 650031
  • Received:1900-01-01 Revised:1900-01-01 Online:1999-02-28 Published:1999-02-28

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Abstract: 　A IM: To investigate the excretion of sporocysts and clinicalm anifestations in humans experimentally infected of Sarcocystis hominis. METHODS: Three vo lunteers were infected by eating raw beef containing cysts of S.hominis. One ingested about 1567 cysts in skeletalmuscles of a naturally infected cattle; two volunteers each ingested about 14740 cysts from an experimentally infected water buffalomeat. Fecalex-amination by zinc sulfate flotation m ethod was conducted daily sinced4 post infection (pi). RESULTS: ree
spo rocyst s and oocysts were found in their faeces from d11～40, d12～ 23, d10～30 pi , and peaked at d18, d14, d14.All of them presented clinical symp toms such as abdominal pain, distension, watery diarrhea and eosinoph ilia 1 w k～4 wkpi and were spontaneou slycured with in 29 days piwithout taking any medicine.CONCLUSION: All the experime tally infected persons had gast rointest inal symptoms and passed sporo-cysts and oocysts in faeces 10～ 12 days after infection and persisted for 11～29 days.

Key words: Sarcocy stis hominis, experimental infection, sporocyst, clinical symptoms, 　hemogram