Abstract: 　Objective] To identify the diagnosis of 14 cases with “kala-azar” previously reported in Hubei Province since 1989 and to evaluate the present status of the disease. [Methods] Bone marrow smear, immunological test (LDTand IFAT), mouse inoculation, fungi culture, vector ( Phlebotomus ) and reservoir host (dog) survey. [Results] Among the 14 cases, 12 cases were progressive disseminated histoplasmois, one was an imported case and another one was a remnant skin type“kala-azar” case. An immunological survey was conducted during 1997～1999 in 25 townships located in 23 counties of 9 prefectures and cities. A total of 13 890 persons had been examined by LDT, the positive rate was 0.07% , no positive case was found among the persons under 40 years of age. During the survey, 1 756 persons had been examined by IFAT, the results were negative .No Phlebotomus chinensis had been found in the surveyed area . A total of 302 dogs were examined, no sick dog had been found. [Conclusion]Kala-azar has been eradicated in Hubei Province.

Key words: Kala-azar, epidemiology, LDT, IFAT, progressive disseminated histoplasmois, Phlebotomus.