›› 2000, Vol. 18 ›› Issue (3): 12-166.

• 论著 • Previous Articles     Next Articles

DETECTION OF TOXOPLASMA INFECTION IN WOMEN WITH GYNAECOLOGIC NEOPLASMS USING ELISA 

HUANG He 1;YAN Fu hua 2;LI Chuan jiang 1;ZHAO Mei yi 2;TANG Jun wen 2;LI Xiang rong 2   

  1. 1 Institute of Virology;Hubei Academy of Medical Sciences;Wuhan 430079 2 Department of Gynaecology;Hubei Cancer Hospital;Wuhan 430079
  • Received:1900-01-01 Revised:1900-01-01 Online:2000-06-30 Published:2000-06-30

Abstract:  Objective] To understand the concurrent in Toxoplasma infection among women with cervical cancer. [Methods] The anti Toxoplasma IgG, IgM antibodies (Abs) and circulating antigens (CAg) in 247 sera ( from 50 cases with cervical cancer in group 1, 59 cases with gynaecological benign tumors in group 2 and 138 cases with other diseases in group 3 ) were detected by ELISA. [Results] The total positive rates of the CAg and the Abs in the three groups were 44 0% (22/50), 25 4% (15/59) and 20 3% (28/138), respectively. The positive rates were 20 0%, 11 9% and 10 9%, respectively for IgG 20 0%, 13 6% and 8 7%, respectively fot IgM and 14 0%, 5 1% and 1 4% respectively for CAg. [Conclusion] The Toxoplasma infection rate of the cervical cancer group was higher than those of the other two groups, particularly the positive rates of CAg and IgM.

Key words: Toxoplasma infection, cervical neoplasms, ELISA, circulating antigen, IgM, IgG.