2015—2022年江苏省棘球蚴病网络报告病例流行病学特征分析

doi:10.12140/j.issn.1000-7423.2023.05.017

中国寄生虫学与寄生虫病杂志 ›› 2023, Vol. 41 ›› Issue (5): 636-639.doi: 10.12140/j.issn.1000-7423.2023.05.017

2015—2022年江苏省棘球蚴病网络报告病例流行病学特征分析

倪碧娴¹(), 徐祥珍¹, 张强¹, 唐凤¹, 张嘉尧¹, 茅范贞¹, 戴洋¹^,², 刘耀宝¹^,²^,^*(), 曹俊¹^,²

1 国家卫生健康委员会寄生虫病预防和控制技术重点实验室，江苏省寄生虫与媒介控制技术重点实验室，江苏省医学重点实验室，江苏省血吸虫病防治研究所，无锡 214064
2 南京医科大学全球健康中心，江苏南京 211166

收稿日期:2023-05-08 修回日期:2023-09-08 出版日期:2023-10-30 发布日期:2023-11-06
通讯作者: *刘耀宝（1981-），男，博士，副研究员，从事寄生虫病防治研究。E-mail：yaobao0721@163.com
作者简介:倪碧娴（1988-），女，硕士，主管医师，从事寄生虫病防治研究。E-mail：doris881018@126.com

Epidemiological characteristics of echinococcosis cases reported in the National Notifiable Disease Report System in Jiangsu Province, 2015—2022

NI Bixian¹(), XU Xiangzhen¹, ZHANG Qiang¹, TANG Feng¹, ZHANG Jiayao¹, MAO Fanzhen¹, DAI Yang¹^,², LIU Yaobao¹^,²^,^*(), CAO Jun¹^,²

1 Key Laboratory of Parasitic Disease Prevention and Control Technology of National Health Council, Key Laboratory of Parasite and Vector Control Technology of Jiangsu Province, Jiangsu Provincial Medical Key Laboratory, Jiangsu Institute of Parasitic Diseases, Wuxi 214064, China
2 Global Health Center of Nanjing Medical University, Nanjing 211166, Jiangsu, China

Received:2023-05-08 Revised:2023-09-08 Online:2023-10-30 Published:2023-11-06
Contact: *E-mail: yaobao0721@163.com

摘要/Abstract

摘要：

通过中国疾病预防控制信息系统收集2015—2022年江苏省棘球蚴病报告病例资料并进行个案流行病学调查，选择既往疑似本地病例集中出现的溧阳市及宜兴市2个棘球蚴病重点地区开展中间宿主、终末宿主感染情况调查，每年在两市屠宰场抽取100~200份羊脏器样品，采用内脏剖检法检查羊棘球蚴感染情况，采集1~3个行政村不少于100只家犬的粪样，ELISA检测犬粪棘球绦虫抗原。采用PASW 18.0对报告病例的时间、地区、人群分布、诊疗情况和中间宿主、终末宿主监测结果等进行描述性分析。结果显示，2015—2022年，江苏省累计报告棘球蚴病病例29例，其中确诊病例占62.07%（18/29），临床诊断病例占37.93%（11/29）。疑似本地感染病例共14例，外地输入性病例共15例。输入性病例中12例来源于新疆，2例来源于西藏，1例来源于巴基斯坦。常州市报告病例数最多，为13例（其中10例为溧阳市的疑似本地感染病例）。报告的29例病例中，男性、女性报告病例数分别占34.48%（10/29）和65.52%（19/29）；40~60岁报告病例数最多，占51.73%（15/29）；职业以农民为主，占41.38%（12/29）。报告病例均为细粒棘球蚴病，上腹部不适等症状出现最多，占51.72%（15/29），主要寄生部位为肝（93.10%，27/29）。75.86%（22/29）的病例接受了手术治疗。终宿主犬棘球绦虫粪抗原阳性率为0.74%（15/2 028），且在其中的2份犬粪中发现了疑似棘球绦虫虫卵。2015—2022年江苏省每年均有棘球蚴病病例报告，除输入病例外，还存在疑似本地感染病例，局部地区可能存在棘球蚴病传播链，后续应强化棘球蚴病监测，针对重点地区和重点人群积极开展棘球蚴病筛查和健康教育工作。

关键词: 棘球蚴病, 江苏省, 报告病例, 流行特征, 防控策略

Abstract:

The data of reported echinococcosis cases in Jiangsu Province from 2015 to 2022 were collected from the Chinese Disease Prevention and Control Information System and epidemiological investigations were conducted on individual cases, while infection of intermediate and terminal hosts was monitored. Two key areas of Liyang City and Yixing City, where suspected local cases have occurred in the past were selected to conduct an investigation on the infection status of intermediate and final hosts of echinococcosis. Every year, 100-200 sheep organ samples were collected from slaughterhouses in both cities, and visceral dissection was used to check the infection status of Echinococcus. Fecal samples from at least 100 dogs in 1-3 administrative villages were collected, and canine fecal Echinococcus antigen was detected by ELISA. A descriptive analysis was performed using PASW 18.0 to analyze the time, region, population distribution, treatment status, and surveillance results of intermediate and terminal hosts. From 2015 to 2022, a total of 29 cases of echinococcosis were reported in Jiangsu Province, of which 62.07% (18/29) were confirmed cases, and 37.93% (11/29) were clinically diagnosed cases. There were 14 suspected local cases and 15 imported cases. Twelve of the imported cases were from Xinjiang, China, 2 cases from Xizang, China and 1 case from Pakistan. Thirteen reported cases, which was the highest in number, were from Changzhou (10 of which are suspected local cases in Liyang). Among the 29 reported cases, 34.48% (10/29) were male and 65.52% (19/29) were female, 51.72% (15/29) were 40-60 years old, and 41.38% (12/29) were farmers. All cases were cystic echinococcosis, and the symptoms of upper abdominal discomfort accounted for 51.72% (15/29), and the main parasitic site was the liver (93.10%, 27/29). 75.86% (22/29) of the cases received surgical treatment. The fecal antigen-positive rate of canine Echinococcus was 0.74% (15/2 028), and suspected Echinococcus eggs were found in two canine feces. From 2015 to 2022, echinococcosis cases were reported annually in Jiangsu Province, and in addition to imported cases, there were also suspected local cases. The transmission chain of echinococcosis may exist in local areas. Therefore, follow-up surveillance of echinococcosis should be strengthened, and screening and health education should be actively carried out in key areas and populations.

Key words: Echinococcosis, Jiangsu Province, Reported cases, Epidemiological characteristics, Prevention and control strategies

中图分类号:

R532.32

倪碧娴, 徐祥珍, 张强, 唐凤, 张嘉尧, 茅范贞, 戴洋, 刘耀宝, 曹俊. 2015—2022年江苏省棘球蚴病网络报告病例流行病学特征分析[J]. 中国寄生虫学与寄生虫病杂志, 2023, 41(5): 636-639.

NI Bixian, XU Xiangzhen, ZHANG Qiang, TANG Feng, ZHANG Jiayao, MAO Fanzhen, DAI Yang, LIU Yaobao, CAO Jun. Epidemiological characteristics of echinococcosis cases reported in the National Notifiable Disease Report System in Jiangsu Province, 2015—2022[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2023, 41(5): 636-639.

图/表 3

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年份	输入性病例	感染来源地	疑似本地感染病例	病例居住地
2015	2	中国新疆	2	常州溧阳市溧城镇、天目湖镇
2016	1	中国新疆	4	常州溧阳市溧城镇、天目湖镇、社渚镇、戴埠镇
2017	4	中国新疆、西藏	1	常州溧阳市埭头镇
2018	2	中国新疆	3	常州溧阳市溧城镇、戴埠镇，宿迁沭阳县青伊湖镇
2019	1	中国新疆	0	—
2020	1	中国新疆	2	常州溧阳市社渚镇，南京鼓楼区中央门街道
2021	2	中国新疆、西藏	1	无锡宜兴市官林镇
2022	2	中国新疆、巴基斯坦	1	徐州新沂市新安街道

特征	外地输入病例数/例（n = 15）	疑似本地病例数/例（n = 14）
性别
男	7	3
女	8	11
年龄组/岁
20~39	3	6
40~60	11	4
> 60	1	4
职业
农民	6	6
工人	3	0
离退人员	1	2
家务人员	4	5
商业服务	1	1

年份	犬粪抗原		羊肝脏及肺脏
年份	检测份数	阳性份数	检测份数	病变份数
2015	353	0	825	0
2016	257	2	910	0
2017	154	2	400	0
2018	365	6	300	0
2019	360	5	552	0
2020	279	0	651	0
2021	260	0	650	0
2022	0	0	600	0
合计	2 028	15	4 888	0

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2015—2022年江苏省棘球蚴病网络报告病例流行病学特征分析

Epidemiological characteristics of echinococcosis cases reported in the National Notifiable Disease Report System in Jiangsu Province, 2015—2022

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