福州市530例疥疮患者流行病学特征分析

doi:10.12140/j.issn.1000-7423.2026.04.025

摘要/Abstract

摘要：

为了解福州市第一总医院皮肤病防治院门诊疥疮患者的流行病学特征，收集2024年1月1日至2025年12月31日在门诊经皮肤镜检查确诊并符合纳入标准的530例疥疮患者临床资料，采用描述性流行病学方法分析患者的性别、年龄、皮损部位及确诊时间。结果显示，530例患者中，男性284例，女性246例，男女性别比约1.2: 1。年龄为10个月~95岁，其中0~14岁、15~34岁、35~59岁、60~69岁、70~79岁、80~99岁分别占12.3%（65/530）、24.9%（132/530）、17.7%（94/530）、12.3%（65/530）、16.6%（88/530）、16.2%（86/530）。所有患者皮肤均有瘙痒及搔抓表现，皮损部位以手掌及手指缝最常见，占90.6%（480/530）；阴囊及阴茎、臀部及肛周、胸部及腹部、下肢、足底及足背、前臂、腋窝、背部分别占3.4%（18/530）、1.5%（8/530）、1.5%（8/530）、0.4%（2/530）、0.9%（5/530）、0.8%（4/530）、0.5%（3/530）、0.4%（2/530）。患者皮损部位镜下均可见隧道样结构，弯曲白色线的末端可见褐色三角形斑。1—8月病例数总体较为平稳，9—11月明显上升，11月达峰值。福州市第一总医院皮肤病防治院门诊确诊的疥疮病例中，60岁及以上人群占比较高，皮损主要累及手掌及手指缝，确诊病例在秋季呈增加趋势。

关键词: 疥疮, 流行病学调查, 人群分布, 福州

Abstract:

To investigate the epidemiological features of patients with scabies attending the Outpatient Department, Institute of Dermatology, Fuzhou First General Hospital, the medical records of 530 patients with scabies with definitive diagnosis by dermoscopy and meeting the inclusion criteria in the Outpatient Department during the period between January 1, 2024 and December 31, 2025 were retrospectively collected, and the gender and age distributions, lesion sites, and time of definitive diagnosis were analyzed among patients with scabies using a descriptive epidemiological method. Among the 530 patients, there were 284 men and 246 women, with a male-to-female ratio of approximately 1.2: 1, and these patients had ages of 10 months to 95 years, with 12.3% (65/530) aged of 0 to 14 years, 24.9% (132/530) aged of 15 to 34 years, 17.7% (94/530) aged of 35 to 59 years, 12.3% (65/530) aged of 60 to 69 years, 16.6% (88/530) aged of 70 to 79 years, and 16.2% (86/530) aged of 80 to 99 years, respectively. All patients presented with pruritus and signs of scratching, and the most common sites of skin injury were palms and interdigital spaces (90.6%, 480/530), followed by scrotum and penis (3.4%, 18/530), buttocks and perianal region (1.5%, 18/530), chest and abdomen (1.5%, 8/530), lower extremities (0.4%, 2/530), bottom and dorsum of the foot (0.9%, 5/530), forearms (0.8%, 4/530), axillae (0.5%, 3/530), and back (0.4%, 2/530), respectively. Dermoscopy of skin lesions showed tunnel-like structures and brown triangle spots in the end of curved white curves. The number of scabies cases remained relatively stable from January through August, increased remarkably from September to November, and peaked in November. There is a high proportion of individuals at ages of 60 years and older among patients with definitive diagnosis of scabies in the Outpatient Department, Institute of Dermatology, Fuzhou First General Hospital, and the most common sites of skin injury are palms and interdigital spaces. The number of patients with definitive diagnosis of scabies appeared a tendency towards an increase in autumn.

Key words: Scabies, Epidemiological investigation, Population distribution, Fuzhou

中图分类号:

R757.1

景月娥, 王莉莉, 陈俊, 翁立强, 龙琴琴. 福州市530例疥疮患者流行病学特征分析[J]. 中国寄生虫学与寄生虫病杂志, 2026, 44(4): 623-625.

JING Yue’e, WANG Lili, CHEN Jun, WENG Liqiang, LONG Qinqin. Epidemiological characteristics of 530 patients with scabies in Fuzhou City[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2026, 44(4): 623-625.

图/表 2

参考文献 17

[1]	Li J, Liu Z, Xia X. The disability-adjusted life years (DALYs), prevalence and incidence of scabies, 1990-2021: a systematic analysis from the Global Burden of Disease Study 2021[J]. PLoS Negl Trop Dis, 2024, 18(12): e0012775.
[2]	金秋百, 刘欣茜, 吴琳, 等. 1990-2021年我国皮肤及皮下组织疾病负担变化趋势分析[J]. 皮肤科学通报, 2026, 43(2): 161-169.
	Jin QB, Liu XQ, Wu L, et al. Analysis of the trend in the burden of skin and subcutaneous tissue diseases in China 1990-2021[J]. Dermatol Bull, 2026, 43(2): 161-169. (in Chinese)
[3]	孙纯鸽, 郑良, 王辉. 一起ICU工作人员结痂型疥疮感染暴发的调查与处置[J]. 中华医院感染学杂志, 2025, 35(16): 2437-2440.
	Sun CG, Zheng L, Wang H. Investigation and management of a crusted scabies outbreak among ICU staff[J]. Chin J Nosocomiology, 2025, 35(16): 2437-2440. (in Chinese)
[4]	杨艺琳, 初同胜, 蔡立好, 等. 济南市某养老院疥疮暴发事件流行病学调查[J]. 中国麻风皮肤病杂志, 2025, 41(10): 710-711.
	Yang YL, Chu TS, Cai LH, et al. Epidemiological investigation of a scabies outbreak in a nursing home in Jinan City[J]. China J Lepr Skin Dis, 2025, 41(10): 710-711. (in Chinese)
[5]	Sharaf MS. Scabies: immunopathogenesis and pathological changes[J]. Parasitol Res, 2024, 123(3): 149.
[6]	Thomas C, Coates SJ, Engelman D, et al. Ectoparasites scabies[J]. J Am Acad Dermatol, 2020, 82(3): 533-548.
[7]	Zhang G, Cui M, Zhang Y, et al. Clinical features of 170 Chinese scabies cases and the therapeutic efficacy of sulfur ointment[J]. PLoS Negl Trop Dis, 2026, 20(7): e0014493.
[8]	Engelman D, Yoshizumi J, Hay RJ, et al. The 2020 international alliance for the control of scabies consensus criteria for the diagnosis of scabies[J]. Br J Dermatol, 2020, 183(5): 808-820.
[9]	孟如松, 崔勇. 多模态皮肤病医学影像诊断图谱[M]. 北京: 人民卫生出版社, 2021: 477-478.
	Meng RS, Cui Y. Medical image diagnosis atlas of multimodal dermatosis[M]. Beijing: People’s Medical Publishing House, 2021: 477-478. (in Chinese)
[10]	Hengge UR, Currie BJ, Jäger G, et al. Scabies: a ubiquitous neglected skin disease[J]. Lancet Infect Dis, 2006, 6(12): 769-779.
[11]	Cassell JA, Middleton J, Nalabanda A, et al. Scabies outbreaks in ten care homes for elderly people: a prospective study of clinical features, epidemiology, and treatment outcomes[J]. Lancet Infect Dis, 2018, 18(8): 894-902.
[12]	林慧艳, 王欢, 顾晓峰, 等. 一起重症医学科疥疮暴发的防控[J]. 军事医学, 2025, 49(4): 318-320.
	Lin HY, Wang H, Gu XF, et al. Infection control of a scabies outbreak in an intensive care unit[J]. Mil Med Sci, 2025, 49(4): 318-320. (in Chinese)
[13]	吴跃, 曹召武, 张辉. 住校学生疥疮患者152例分析[J]. 中国校医, 2021, 35(3): 185-187.
	Wu Y, Cao ZW, Zhang H. Analysis of prevalence state and infection factors of 152 residential students with scabies[J]. Chin J Sch Doctor, 2021, 35(3): 185-187. (in Chinese)
[14]	Bhat SA, Walton SF, Ventura T, et al. Early immune suppression leads to uncontrolled mite proliferation and potent host inflammatory responses in a porcine model of crusted versus ordinary scabies[J]. PLoS Negl Trop Dis, 2020, 14(9): e0008601.
[15]	Kim HS, Hashimoto T, Fischer K, et al. Scabies itch: an update on neuroimmune interactions and novel targets[J]. J Eur Acad Dermatol Venereol, 2021, 35(9): 1765-1776.
[16]	刘香, 牛李莉, 鲁楠, 等. 747例疥疮临床特征分析[J]. 中华全科医师杂志, 2023, 22(10): 1057-1061.
	Liu X, Niu LL, Lu N, et al. Clinical characteristics of scabies: an analysis of 747 cases[J]. Chin J Gen Pract, 2023, 22(10): 1057-1061. (in Chinese)
[17]	Halder CE, Hasan MA, kello JC, et al. Seasonality of scabies and itsassociation with climatic factors in Rohingya refugeecamps, Cox’s Bazar: a retrospective observationalstudy, 2021-2023[J]. BMJ Open, 2026, 16: el17016.