迭宫属绦虫的分类学研究进展

doi:10.12140/j.issn.1000-7423.2024.01.014

中国寄生虫学与寄生虫病杂志 ›› 2024, Vol. 42 ›› Issue (1): 98-104.doi: 10.12140/j.issn.1000-7423.2024.01.014

迭宫属绦虫的分类学研究进展

张玺(), 茹丝丝, 龙绍蓉, 刘若丹, 姜鹏, 崔晶, 王中全^*()

郑州大学基础医学院病原生物学系，河南郑州 450001

收稿日期:2023-10-18 修回日期:2024-01-02 出版日期:2024-02-28 发布日期:2024-03-12
通讯作者: *王中全（1959—），男，硕士，教授，从事寄生虫学研究。E-mail: wangzq@zzu.edu.cn
作者简介:张玺（1984—），男，博士，教授，从事寄生虫学研究。E-mail: zhangxi@zzu.edu.cn
基金资助:
国家自然科学基金面上项目(81971956);河南省高等学校重点科研项目计划基础研究专项(24ZX003);国家科技基础条件平台国家寄生虫资源库项目(NPRC-2019-194-30)

Research advances on the taxonomy of Spirometra tapeworms

ZHANG Xi(), RU Sisi, LONG Shaorong, LIU Ruodan, JIANG Peng, CUI Jing, WANG Zhongquan^*()

Department of Pathogens, Basic Medical College, Zhengzhou University, Zhengzhou 450001, Henan, China

Received:2023-10-18 Revised:2024-01-02 Online:2024-02-28 Published:2024-03-12
Contact: *E-mail: wangzq@zzu.edu.cn
Supported by:
National Natural Science Foundation of China(81971956);Basic Research Program of Key Research Project Plan in Higher Education Institutions in Henan Province(24ZX003);National Science and Technology Basic Conditions Platform National Parasite Resource Database Project(NPRC-2019-194-30)

摘要/Abstract

摘要：

迭宫属绦虫是一类被长期忽视的医学绦虫类群，其中绦期幼虫裂头蚴可侵入人体多种组织和器官引起裂头蚴病，造成较大危害。迭宫绦虫的分类系统一直较混乱，给相关的科研和教学工作带来困难。本文对迭宫绦虫的系统地位变迁及其分类学研究进展进行系统综述，以期为相关问题提供答案，同时为相关物种的研究提供参考资料。

关键词: 迭宫绦虫, 分类学, 研究进展

Abstract:

The genus Spirometra is a group of medical tapeworms that have been neglected for a long time. Its plerocercoid larvae can parasitize different tissues and organs in humans, causing a food/water-borne parasitic zoonosis known as sparganosis. The classification system of Spirometra was controversial for a extended period of time, causing confusion for related scientific research and teaching. In this paper, we provided a systematic review of systematic changes and taxonomic research progress of Spirometra tapeworms, to find appropriate answers to relevant questions and lay foundation for the study of related species.

Key words: Spirometra tapeworm, Taxonomy, Research advance

中图分类号:

R383.3

张玺, 茹丝丝, 龙绍蓉, 刘若丹, 姜鹏, 崔晶, 王中全. 迭宫属绦虫的分类学研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2024, 42(1): 98-104.

ZHANG Xi, RU Sisi, LONG Shaorong, LIU Ruodan, JIANG Peng, CUI Jing, WANG Zhongquan. Research advances on the taxonomy of Spirometra tapeworms[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2024, 42(1): 98-104.

图/表 3

表1

表2

表3

参考文献 53

[1]	Kuchta R, Ko?odziej-Sobocińska M, Brabec J, et al. Sparganosis (Spirometra) in Europe in the molecular era[J]. Clin Infect Dis, 2021, 72(5): 882-890.
[2]	Liu Q, Li MW, Wang ZD, et al. Human sparganosis, a neglected food borne zoonosis[J]. Lancet Infect Dis, 2015, 15(10): 1226-1235.
[3]	Eberhard ML, Thiele EA, Yembo GE, et al. Thirty-seven human cases of sparganosis from Ethiopia and South Sudan caused by Spirometra spp.[J]. Am J Trop Med Hyg, 2015, 93(2): 350-355.
[4]	Kim JG, Ahn CS, Sohn WM, et al. Human sparganosis in Korea[J]. J Korean Med Sci, 2018, 33(44): e273.
[5]	Cui J, Wang Y, Zhang X, et al. A neglected risk for sparganosis: eating live tadpoles in central China[J]. Infect Dis Poverty, 2017, 6: 58.
[6]	Hu DF, Jin WX, Ding HR, et al. Spirometra mansoni sparganosis identified by metagenomic next-generation sequencing: a case report[J]. Int J Infect Dis, 2023, 128: 128-131.
[7]	Qiu MH, Qiu MD. Human plerocercoidosis and sparganosis: Ⅰ. A historical review on aetiology[J]. Chin J Parasitol Parasit Dis, 2009, 27(1): 54-60. (in Chinese)
	(裘明华, 裘明德. 人裂头蚴病和无头蚴病: Ⅰ. 病原学的过去和现在[J]. 中国寄生虫学与寄生虫病杂志, 2009, 27(1): 54-60.)
[8]	Wu GL. Human parasitology[M]. 4th ed. Beijing: People’s Health Press, 2013: 437-539. (in Chinese)
	(吴观陵. 人体寄生虫学[M]. 4版. 北京: 人民卫生出版社, 2013: 437-539.)
[9]	Hoberg EP, Mariaux J, Justine JL, et al. Phylogeny of the orders of the Eucestoda (Cercomeromorphae) based on comparative morphology: historical perspectives and a new working hypothesis[J]. J Parasitol, 1997, 83(6): 1128-1147.
[10]	Mariaux J. A molecular phylogeny of the Eucestoda[J]. J Parasitol, 1998, 84(1): 114-124.
[11]	Kodedová I, Dole?el D, Brou?ková M, et al. On the phylogenetic positions of the Caryophyllidea, Pseudophyllidea and Proteocephalidea (Eucestoda) inferred from 18S rRNA[J]. Int J Parasitol, 2000, 30(10): 1109-1113.
[12]	Olson PD, Littlewood DT, Bray RA, et al. Interrelationships and evolution of the tapeworms (Platyhelminthes : Cestoda)[J]. Mol Phylogenet Evol, 2001, 19(3): 443-467.
[13]	Brabec J, Kuchta R, Scholz T. Paraphyly of the Pseudophyllidea (Platyhelminthes ∶ Cestoda): circumscription of monophyletic clades based on phylogenetic analysis of ribosomal RNA[J]. Int J Parasitol, 2006, 36(14): 1535-1541.
[14]	Waeschenbach A, Webster BL, Bray RA, et al. Added resolution among ordinal level relationships of tapeworms (Platyhelminthes ∶ Cestoda) with complete small and large subunit nuclear ribosomal RNA genes[J]. Mol Phylogenet Evol, 2007, 45(1): 311-325.
[15]	Kuchta R, Scholz T, Brabec J, et al. Suppression of the tapeworm order Pseudophyllidea (Platyhelminthes ∶ Eucestoda) and the proposal of two new orders, Bothriocephalidea and Diphyllobothriidea[J]. Int J Parasitol, 2008, 38(1): 49-55.
[16]	Kuchta R, Scholz T. Diphyllobothriidea[M]//Caira JN, Jensen J. Tapeworms from vertebrate bowels of the earth 2008—2017. Lawrence: University of Kansas, 2017: 167-189.
[17]	Caira JN, Jensen K, Healy CJ. On the phylogenetic relationships among tetraphyllidean, lecanicephalidean and diphyllidean tapeworm genera[J]. Syst Parasitol, 1999, 42(2): 77-151.
[18]	Waeschenbach A, Brabec J, Scholz T, et al. The catholic taste of broad tapeworms: multiple routes to human infection[J]. Int J Parasitol, 2017, 47(13): 831-843.
[19]	Scholz T, Kuchta R, Brabec J. Broad tapeworms (Diphyllobothriidae), parasites of wildlife and humans: recent progress and future challenges[J]. Int J Parasitol Parasites Wildl, 2019, 9: 359-369.
[20]	Li HY. Foundation of cestodology[M]. Beijing: Science Press, 2021: 163-189. (in Chinese)
	(李海云. 绦虫学基础[M]. 北京: 科学出版社, 2021: 163-189.)
[21]	Li HY. Classification system adjustment of Pseudophyllidea and the identification characteristics of the main taxa[J]. Chin J Parasitol Parasit Dis, 2022, 40(3): 411-419. (in Chinese)
	(李海云. 假叶目绦虫的分类系统调整及其主要类群的识别特征[J]. 中国寄生虫学与寄生虫病杂志, 2022, 40(3): 411-419.)
[22]	von Bonsdorff B. Diphyllobothriasis in man[M]. London: Academic Press, 1977: 189.
[23]	Jimenez JA, Rodriguez S, Gamboa R, et al. Diphyllobothrium pacificum infection is seldom associated with megaloblastic anemia[J]. Am J Trop Med Hyg, 2012, 87(5): 897-901.
[24]	Faust EC, Campbell HE, Kellogg CR. Morphological and biological studies on the species of Diphyllobothrium in China[J]. Am J Epidemiol, 1929, 9(3): 560-583.
[25]	Mueller JF. A repartition of the genus Diphyllobothrium[J]. J Parasitol, 1937, 23(3): 308.
[26]	Schmidt GD. CRC handbook of tapeworm identification[M]. Florida: CRC Press, 1986: 81-115.
[27]	Mueller JF. The biology of Spirometra[J]. J Parasitol, 1974, 60(1): 3-14.
[28]	Iwata S. Experimental and morphological studies of Manson’s tapeworm Diphyllobothrium erinacei (Rudolphi): special reference with its scientific name and relationship with Sparganum proliferum Ijima[J]. Prog Med Parasitol Jpn, 1972, 4: 535-590.
[29]	Okamoto M, Iseto C, Shibahara T, et al. Intraspecific variation of Spirometra erinaceieuropaei and phylogenetic relationship between Spirometra and Diphyllobothrium inferred from mitochondrial CO1 gene sequences[J]. Parasitol Int, 2007, 56(3): 235-238.
[30]	Zhang X, Wang H, Cui J, et al. Characterisation of the relationship between Spirometra erinaceieuropaei and Diphyllobothrium species using complete cytb and cox1 genes[J]. Infect Genet Evol, 2015, 35: 1-8.
[31]	Zhang X, Duan JY, Shi YL, et al. Comparative mitochondrial genomics among Spirometra (Cestoda ∶ Diphyllobothriidae) and the molecular phylogeny of related tapeworms[J]. Mol Phylogenet Evol, 2017, 117: 75-82.
[32]	Kamo H. Guide to Identification of Diphyllobothriid cestodes[M]. Tokyo: GendaiKikaku, 1999: 1-146.
[33]	Jeon HK, Park H, Lee DM, et al. Genetic and morphologic identification of Spirometra ranarum in Myanmar[J]. Korean J Parasitol, 2018, 56(3): 275-280.
[34]	Eom KS, Park H, Lee DM, et al. Identity of Spirometra theileri from a leopard (Panthera pardus) and spotted hyena (Crocuta crocuta) in Tanzania[J]. Korean J Parasitol, 2019, 57(6): 639-645.
[35]	Zhang X, Hong X, Liu SN, et al. Large-scale survey of a neglected agent of sparganosis Spirometra erinaceieuropaei (Cestoda ∶ Diphyllobothriidae) in wild frogs in China[J]. PLoS Negl Trop Dis, 2020, 14(2): e0008019.
[36]	Yamasaki H, Sanpool O, Rodpai R, et al. Spirometra species from Asia: genetic diversity and taxonomic challenges[J]. Parasitol Int, 2021, 80: 102181.
[37]	McHale B, Callahan RT, Paras KL, et al. Sparganosis due to Spirometra sp. (Cestoda; Diphyllobothriidae) in captive meerkats (Suricata suricatta)[J]. Int J Parasitol Parasites Wildl, 2020, 13: 186-190.
[38]	Arrabal JP, Pérez MG, Arce LF, et al. First identification and molecular phylogeny of Sparganum proliferum from endangered felid (Panthera onca) and other wild definitive hosts in one of the regions with highest worldwide biodiversity[J]. Int J Parasitol Parasites Wildl, 2020, 13: 142-149.
[39]	Fredes F, Mercado R, Salas IP, et al. Morphological observation and molecular phylogeny of Spirometra decipiens complex 1 (Cestoda ∶ Diphyllobothriidae) found in cat from Chile[J]. Parasitol Int, 2022, 87: 102493.
[40]	Zhang X, Wang H, Cui J, et al. The phylogenetic diversity of Spirometra erinaceieuropaei isolates from southwest China revealed by multi genes[J]. Acta Trop, 2016, 156: 108-114.
[41]	Zhang X, Hong X, Duan JY, et al. Development of EST-derived microsatellite markers to investigate the population structure of sparganum: the causative agent of zoonotic sparganosis[J]. Parasitology, 2019, 146(7): 947-955.
[42]	Xu FF, Chen WQ, Liu W, et al. Genetic structure of Spirometra mansoni (Cestoda ∶ Diphyllobothriidae) populations in China revealed by a target SSR-seq method[J]. Parasit Vectors, 2022, 15(1): 485.
[43]	Ko?odziej-Sobocińska M, Stojak J, Kondzior E, et al. Genetic diversity of two mitochondrial DNA genes in Spirometra erinaceieuropaei (Cestoda ∶ Diphyllobothridae) from Poland[J]. J Zool Syst Evol Res, 2019, 57(4): 764-777.
[44]	Hong X, Liu SN, Xu FF, et al. Global genetic diversity of Spirometra tapeworms[J]. Trop Biomed, 2020, 37(1): 237-250.
[45]	Bagrade G, Králová-Hromadová I, Bazsalovicsová E, et al. The first records of Spirometra erinaceieuropaei (Cestoda ∶ Diphyllobothriidae), a causative agent of human sparganosis, in Latvian wildlife[J]. Parasitol Res, 2021, 120(1): 365-371.
[46]	Okino T, Yamasaki H, Yamamoto Y, et al. A case of human breast sparganosis diagnosed as Spirometra Type Ⅰ by molecular analysis in Japan[J]. Parasitol Int, 2021, 84: 102383.
[47]	Chen WQ, Liu SS, Cheng C, et al. Molecular characteristics of glutathione transferase gene family in a neglect medical Spirometra tapeworm[J]. Front Vet Sci, 2022, 9: 1035767.
[48]	Wang RJ, Li W, Liu SN, et al. Integrated transcriptomic and proteomic analyses of plerocercoid and adult Spirometra mansoni reveal potential important pathways in the development of the medical tapeworm[J]. Parasit Vectors, 2023, 16(1): 316.
[49]	Liu SN, Gao F, Wang RJ, et al. Molecular characteristics of the fatty-acid-binding protein (FABP) family in Spirometra mansoni: a neglected medical tapeworm[J]. Animals, 2023, 13(18): 2855.
[50]	Brabec J, Uribe M, Chaparro-Gutiérrez JJ, et al. Presence of Spirometra mansoni, causative agent of sparganosis, in South America[J]. Emerg Infect Dis, 2022, 28(11): 2347-2350.
[51]	Uribe M, Brabec J, Chaparro-Gutiérrez JJ, et al. Neglected zoonotic helminthiases in wild canids: new insights from South America[J]. Front Vet Sci, 2023, 10: 1235182.
[52]	Verocai GG, Harvey TV, Sobotyk C, et al. Spirometra infection in a captive Samar cobra (Naja samarensis) in the United States: an imported case?[J]. Int J Parasitol Parasites Wildl, 2023, 20: 133-137.
[53]	Yamasaki H, Sugiyama H, Morishima Y, et al. Description of Spirometra asiana sp. nov. (Cestoda ∶ Diphyllobothriidae) found in wild boars and hound dogs in Japan[J]. Parasitol Int, 2024, 98: 102798.

分类阶元	阶元变迁事件	参考文献
假叶目	一直被认为是一个单系类群，典型特征是头节具有两个吸槽	[8]
	假叶目绦虫的单系性遭质疑，并提出该类群是并系或多系的假说	[9]
	证实假叶目绦虫类群的多系性	[10⇓-12]
	将假叶目拆分为“Diphyllobothriidea”和“Bothriocephalidea”两个支系	[13]
“Diphyllobothriidea”支系	明确“Diphyllobothriidea”支系包括双叶槽科（Diphyllobothriidae）和头衣科（Cephalochlamydidae）2个科	[13]
“Diphyllobothriidea”支系	证明“Diphyllobothriidea”与单槽目（Haplobothriidea）、鲤蠢目（Caryophyllidea）及佛焰苞槽目（Spathebothriidea）具有较近的亲缘关系	[14]
“Bothriocephalidea”支系	明确“Bothriocephalidea”支系包括槽首科（Bothrioephalidae）、棘阴茎科（Echinophalidae）、亲深海科（Philobythidae）和三支钩科（Trianeophoridae）4个科	[13]
“Bothriocephalidea”支系	提出“Bothriocephalidea”支系系统进化关系关系较为混乱，同时质疑槽首科、棘阴茎科和三支钩科的单系性	[14]
双叶槽目	将“Diphyllobothriidea”支系确立为双叶槽目（Diphyllobothriidea），并将管孔科（Solenophoridae）划归该目，明确钵头科（Scyphocephalidae）为管孔科的同物异名	[15-16]
双叶槽目	进一步证实双叶槽目与单槽目和鲤蠢目亲缘关系较近	[16]
槽首目	将“Bothriocephalidea”支系确立为槽首目（Bothriocephalidea），包括槽首科、棘阴茎科、亲深海科和三支钩科4个科	[15]
槽首目	提出槽首目与吸臼类绦虫（acetabulate）的姊妹群关系，但需要进一步验证	[16]

编号	有效属属名	参考文献
1	Diphyllobothrium Cobbold, 1858^a	[15,18]
2	Baylisia Markowski, 1952	[15]
3	Baylisiella Markowski, 1952	[15]
4	Diplogonoporus Lönnberg, 1892^a	[15,18]
5	Flexobothrium Yurakhno, 1979a	[15,20]
6	Glandicephalus Fuhrmann, 1921	[15]
7	Ligula Bloch, 1782	[15]
8	Plicobothrium Rausch & Margolis, 1969	[15]
9	Pyramicocephalus Monticelli, 1890^a	[15,20]
10	Schistocephalus Creplin, 1829	[15]
11	Spirometra Faust, Campbell & Kellogg, 1929	[15]
12	Tetragonoporus Skriabin, 1961^a	[15,20]
13	Adenocephalus Nybelin, 1931^a	[16,21]
14	Dibothriocephalus Lühe, 1899^a	[18]
15	Digramma Cholodkowsky, 1915^a	[20]
16	Hexagonoporus Gubanov in Delyamure, 1955^a	[20]
17	Multiductus Clarke, 1962^a	[20]
18	Duthiersia Perrier, 1873^a	[20-21]

物种名	地理分布
曼氏迭宫绦虫 S. mansoni	亚洲：中国、日本、韩国、泰国、越南、缅甸、老挝、印度尼西亚、印度、伊朗；大洋洲：澳大利亚、新西兰；欧洲：罗马尼亚；非洲：坦桑尼亚、毛里求斯；北美洲：美国；南美洲：哥伦比亚
欧猬迭宫绦虫 S. erinaceieuropaei	欧洲：罗马尼亚、波兰、德国、乌克兰、芬兰、拉脱维亚、塞尔维亚、白俄罗斯等
叶形迭宫绦虫 S. folium	非洲：苏丹、埃塞俄比亚、坦桑尼亚
虚假迭宫绦虫混合型1 S. decipiens complex 1	北美洲；南美洲
虚假迭宫绦虫混合型2 S. decipiens complex 2	北美洲；南美洲
亚洲迭宫绦虫 S. asiana	亚洲：日本
未定名迭宫绦虫 Undescribed Spirometra sp. l	亚洲：日本、韩国

迭宫属绦虫的分类学研究进展

Research advances on the taxonomy of Spirometra tapeworms

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

图/表 3

参考文献 53

相关文章 15

编辑推荐

Metrics

本文评价

[1]	郭嘉天, 林琳, 卢艳. 曼氏裂头蚴病诊断技术研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2024, 42(6): 776-782.
[2]	周欣, 黄翠兰. 抗阴道毛滴虫靶点及药物研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2024, 42(1): 105-110.
[3]	陈瑶, 张本光. 异尖属线虫分类学研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2023, 41(4): 480-485.
[4]	徐凯, 黄璐璐, 吴传玲, 李文登, 尹凤娇, 王志鑫, 樊海宁, 王海久. 中药实验治疗棘球蚴病的研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2021, 39(5): 710-715.
[5]	牛子文, 常艳凯, 王克, 张龙现. 隐孢子虫体外培养模型研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2020, 38(3): 394-399.
[6]	胡坤敏, 郑彬, 陈韶红, 艾琳. 并殖吸虫DNA分类技术的研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2019, 37(5): 598-602.
[7]	胡月, 陈艳, 李金福, 蒙兴慧, 刘巧霞, 刘鉴. 虫种特异性基因检测小鼠无虫病理组织裂头蚴感染的可行性研究[J]. 中国寄生虫学与寄生虫病杂志, 2018, 36(4): 357-361.
[8]	尚婧晔, 张光葭, 何伟, 喻文杰, 廖沙, 王奇, 陈凡, 李汭芮, 王谦, 钟波, 黄燕. 细粒棘球蚴病病原分类学与分子流行病学研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2018, 36(2): 166-174.
[9]	张玲玲, 吴斌, 丰燕, 骆小君, 陈华良, 潘金仁, 阮卫, 姚立农. 人体感染曼氏迭宫绦虫成虫的病原体鉴定和流行病学分析[J]. 中国寄生虫学与寄生虫病杂志, 2018, 36(2): 199-封三.
[10]	张勇, 李金福, 陈艳, 蔡倩彤. 猬迭宫绦虫裂头蚴感染小鼠皮下肌肉组织β1转化生长因子含量变化的观察[J]. 中国寄生虫学与寄生虫病杂志, 2017, 35(3): 270-274.
[11]	沈美清*，刘建，杨利群，张红芳，钱华. 人感染曼氏裂头蚴病4例诊治分析[J]. 中国寄生虫学与寄生虫病杂志, 2015, 33(2): 11-125-127.
[12]	宋国平，李金福，陈艳*，徐婧. 雷丸及吡喹酮对猬迭宫绦虫裂头蚴感染性及超微结构的影响[J]. 中国寄生虫学与寄生虫病杂志, 2015, 33(1): 8-40-44.
[13]	吕刚;芦亚君;范志刚;史大中;甘秀凤;钟赛凤. 欧猬迭宫绦虫全长cDNA文库构建及鉴定[J]. 中国寄生虫学与寄生虫病杂志, 2010, 28(5): 18-394.
[14]	唐贵文;陈艳;刘鲜林;常傲霜. 曼氏迭宫绦虫裂头蚴超微结构的观察[J]. 中国寄生虫学与寄生虫病杂志, 2010, 28(4): 19-314.
[15]	蒋红涛;陈艳;唐贵文;陈璐. 曼氏迭宫绦虫裂头蚴可溶性蛋白质的分析[J]. 中国寄生虫学与寄生虫病杂志, 2010, 28(2): 10-132.