中国寄生虫学与寄生虫病杂志 ›› 2013, Vol. 31 ›› Issue (1): 15-64-67.

• 综述 • 上一篇    下一篇

血吸虫蛋白质组学研究进展

徐宏1,2,关飞1,刘文琪1 *   

  1. 1 华中科技大学同济医学院病原生物学系,武汉 430030;2 杭州市第一人民医院检验科,杭州 310058
  • 出版日期:2013-02-28 发布日期:2013-04-23

Advance of Proteomic Research on Schistosome

XU Hong1,2,GUAN Fei1,LIU Wen-qi1 *   

  1. 1 Department of Parasitology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China;2 Department of Laboratory Medicine, The First People’s Hospital of Hangzhou City, Hangzhou 310058, China
  • Online:2013-02-28 Published:2013-04-23

摘要: 血吸虫蛋白质组研究对于血吸虫病免疫机制的阐述、诊断和疫苗分子的发现、新药物靶点的筛选等均有重要意义。本文综述了血吸虫不同虫期的蛋白质组学研究进展。

关键词: 血吸虫, 蛋白质组, 二维电泳, 质谱

Abstract: Schistosome proteome research may greatly enhance the understanding of immune mechanism, exploration of new diagnostic and vaccine candidates, and the development of new drugs. This article reviews the progress of proteomic research on schistosome from different life-cycle stages.

Key words: Schistosome, Proteome, Two-dimensional gel electrophoresis, Mass spectrometry