中国寄生虫学与寄生虫病杂志 ›› 2012, Vol. 30 ›› Issue (5): 14-406-410.

• 综述 • 上一篇    下一篇

犬内脏利什曼病诊断方法的研究进展

丁丹,汪俊云*   

  1. 中国疾病预防控制中心寄生虫病预防控制所,卫生部寄生虫病原与媒介生物学重点实验室,世界卫生组织疟疾、血吸虫病和丝虫病合作中心,上海 200025
  • 出版日期:2012-10-30 发布日期:2013-02-05

Research Progress on the Diagnosis Technology of Canine Visceral Leishmaniasis

DING Dan, WANG Jun-yun*   

  1. National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Laboratory of Parasite and Vector Biology, Ministry of Health; WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Shanghai 200025, China
  • Online:2012-10-30 Published:2013-02-05

摘要: 【提要】  犬内脏利什曼病由婴儿利什曼原虫(Leishmania infantum)感染引起,病犬和无症状感染犬是动物源型内脏利什曼病流行区人内脏利什曼病的主要传染源。对犬内脏利什曼病的诊断是控制动物源型内脏利什曼病的关键,应高度重视诊断方法的研究。本文就犬内脏利什曼病诊断方法的研究进展作一综述。

关键词: 犬内脏利什曼病, 诊断, 病原学方法, 分子生物学方法, 免疫学方法

Abstract:  【Abstract】  Canine visceral leishmaniasis is caused by Leishmania infantum. Infected dogs, either symptomatic or asymptomatic, are considered as the major reservoirs for zoonotic visceral leishmaniasis. Accurate and rapid detection of canine leishmanial infection is crucial for control of human visceral leishmaniasis due to its role in the transmission of the infection to vectors. Various techniques based on parasitology, immunology and molecular biology have been studied and evaluated for detecting canine leishmanial infection. This article reviews the progress in techniques and methods for its diagnosis.

Key words:  Canine visceral leishmaniasis; Diagnosis; Parasitological method; Immunological method;  , Molecular method