中国寄生虫学与寄生虫病杂志 ›› 1990, Vol. 8 ›› Issue (4): 270-273.

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中国大陆日本血吸虫品系的研究——Ⅱ.哺乳动物的易感性

何毅勋,郁琪芳,胡亚青,张永年   

  1. 中国预防医学科学院寄生虫病研究所
  • 出版日期:1990-11-30 发布日期:2017-01-09
  • 基金资助:
    国家自然科学基金

STUDIES ON THE STRAIN DIFFERENCES OF SCHISTOSOMA JAPONICUM IN THE MAINLAND OF CHINA Ⅱ.SUSCEPTIBILITY OF MAMMALIAN HOSTS

  • Online:1990-11-30 Published:2017-01-09

摘要: 本文报告了6种哺乳动物于人工感染安徽、湖北、广西、四川和云南5地日本血吸虫的虫体回收率及其虫卵开放前期。结果表明,C57BL小鼠、金黄仓鼠、长爪沙鼠、家兔和恒河猴均是中国大陆上述5地日本血吸虫的可容宿主,大鼠则是不可容宿主。各种动物感染大陆上述5地日本血吸虫的虫卵开放前期平均天数表明,C57BL小鼠、金黄仓鼠或恒河猴感染云南或广西两地血吸虫的虫卵开放前期均较四川的为长,差别显著。本文指出德国汉堡热带医学研究院提供的或由其转种而传代的日本血吸虫的平均虫卵开放前期明显地较中国大陆各地日本血吸虫自然隔离群的长5~8d,它已不能代表中国大陆品系日本血吸虫的生物学特性,建议将其称为“中国大陆Vogel品系”,以资与中国大陆的加以区别。

关键词: 日本血吸虫, 哺乳动物宿主, 易感性, 品系

Abstract: Six species of animals were percutaneously exposed to cercariae obtained from pools of naturally infected snails from different isolates of S. japonicum in the mainland of China as shown in Tables 1 and 2. Our results indicated that with the exception of rat, all animals under study were permissive host though their worm recovery rates varied with different isolates.The mean prepatent period in different host species were 35.0 ±0.8 to 36.4±1.0 days for Anhui isolate; 34.5±1.2 to 36.4± 1.2 days for Hubei isolate; 34.5±1.3 to 35.8 ±0.6 days for Sichuan isolate; 35.1 ± 1.0 to 37.3 ± 1.9 days for Guangxi isolate and 36.1 ±1.9 to 37.8 +± 0.8 days for Yunnan isolate. In general, the prepatent period was longer in the C57 BL inbred mice, hamsters and rhesus monkeys infected with Yunnan and Guangxi isolates, than that with Sichuan isolate. This result also indicates that the prepatent period of the strain of S. japonicum defined by Dr. Vogel as a Chinese strain which had been originated from the cercariae in infected Oncomelania hupensis hupensis snails from Jiaxing, Zhejiang (Kashing, Chekiang), China, and established in Tropeninstitut in Hamburg since 1937 by repeated passages in dogs and laboratory-bred O. h. hupensis snails, was 5-8 days longer than that of all the isolates under our study, probably due to some behavioral change. We suggest, therefore, that the Vogel's stock of S. japonicum should be termed as "Chinese Vogel strain".