中国寄生虫学与寄生虫病杂志 ›› 2026, Vol. 44 ›› Issue (1): 118-123.doi: 10.12140/j.issn.1000-7423.2026.01.017

• 综述 • 上一篇    下一篇

肝多房棘球蚴病致布-加综合征及门脉高压的研究进展

阿吉德1()(), 柴金萍2, 景钦东1, 潘洪帅1,*()()   

  1. 1 青海省人民医院普外科青海西宁 810000
    2 青海省人民医院心内科青海西宁 810000
  • 收稿日期:2025-06-30 修回日期:2025-09-08 出版日期:2026-02-28 发布日期:2026-02-10
  • 通讯作者: 潘洪帅(ORCID:0009-0006-3641-1022),男,硕士,副主任医师,从事肝脏肿瘤的临床及基础研究。E-mail:164161645@qq.com
  • 作者简介:阿吉德(ORCID:0000-0003-4478-1972),男,博士,副主任医师,从事肝棘球蚴病的临床及基础研究。E-mail:491607355@qq.com
  • 基金资助:
    国家自然科学基金(82260412);2024年青海省昆仑英才-高端创新创业人才-拔尖人才项目(青人才字[2025]5号);青海省人民医院-苏州大学联合培养高层次卫生人才项目专项课题(2025-qhsrmyysd-01);青海省卫生健康委指导性课题(2020-wjzdx-27)

Progress researches on Budd-Chiari syndrome and portal hypertension caused by hepatic alveolar echinococcosis

A Jide1()(), CHAI Jinping2, JING Qindong1, PAN Hongshuai1,*()()   

  1. 1 Department of General Surgery, Qinghai Provincial People’s Hospital, Xining 810007, Qinghai, China
    2 Department of Cardiology, Qinghai Provincial People’s Hospital, Xining 810007, Qinghai, China
  • Received:2025-06-30 Revised:2025-09-08 Online:2026-02-28 Published:2026-02-10
  • Contact: E-mail: 164161645@qq.com
  • Supported by:
    National Natural Science Foundation of China(82260412);2024 Kunlun Talents High-end Innovation and Entrepreneurship Talents of Qinghai Province (Qingrencai Zi [2025] 5);Qinghai Provincial People’s Hospital-Soochow University Joint Training Program of High-Level Health Personnel Project(2025-qhsrmyysd-01);Guiding Project of Qinghai Provincial Health Commission(2020-wjzdx-27)

摘要:

肝多房棘球蚴病是一种被称为“虫癌”的人兽共患寄生虫病。肝多房棘球蚴病灶易沿肝内血管生长,巨大的病灶可直接侵犯或压迫邻近的门静脉、肝静脉主干和下腔静脉肝后段,导致终末期肝多房棘球蚴病患者多合并有不同程度的淤血性肝硬化、布-加综合征或门静脉高压等。这不仅使肝多房棘球蚴病的诊疗工作难度加大,而且增加了疾病治疗的成本。目前,对肝多房棘球蚴病诱发门静脉高压、布-加综合征及淤血性肝硬化等并发症的发病机制尚未完全清楚,诊断和治疗方面尚有争议。本文就肝多房棘球蚴病诱发的淤血性肝硬化、布-加氏综合征及门静脉高压症等临床综合征作一综述。

关键词: 多房棘球蚴病, 淤血性肝硬化, 布-加综合征, 门静脉高压, 肝纤维化

Abstract:

Hepatic alveolar echinococcosis is a zoonotic parasitic disease that is known as the parasite cancer. Lesions of hepatic alveolar echinococcosis tend to grow along the intrahepatic blood vessels, and large lesions may directly invade or compress adjacent portal veins, hepatic vein, trunk, and the post-hepatic segment of the inferior vena cavar esulting in that the majority of patients with end-stage hepatic alveolar echinococcosis are complicated with cardiac cirrhosis, Budd-Chiari syndrome, or portal hypertension at varying degrees. This not only increases the difficulty in diagnosis and treatment for hepatic alveolar echinococcosis, but also raises the cost of disease treatment. Currently, the pathogenesis of hepatic alveolar echinococcosis induced portal hypertension, Budd-Chiari syndrome, and cardiac cirrhosis is not fully understood, and there are still controversies regarding diagnosis and treatment of these complications. This article provides a brief overview of the clinical symptoms induced by hepatic alveolar echinococcosis, including cardiac cirrhosis, Budd-Chiari syndrome, and portal hypertension.

Key words: Alveolar echinococcosis, Cardiac cirrhosis, Budd-Chiari syndrome, Portal hypertension, Liver fibrosis

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