人体挥发物对蚊虫行为影响的研究进展

doi:10.12140/j.issn.1000-7423.2023.01.002

中国寄生虫学与寄生虫病杂志 ›› 2023, Vol. 41 ›› Issue (1): 10-14.doi: 10.12140/j.issn.1000-7423.2023.01.002

人体挥发物对蚊虫行为影响的研究进展

张虹(), 程功^*()

清华大学医学院，北京 100084

收稿日期:2022-11-22 修回日期:2023-01-12 出版日期:2023-02-28 发布日期:2023-02-03
通讯作者: * 程功（1981-），男，博士，教授，从事虫媒病毒性传染病致病机制研究和疫苗研发。 E-mail：gongcheng@mail.tsinghua.edu.cn
作者简介:张虹（1990-），女，博士后，从事蚊媒化学通讯和行为调控机制研究。E-mail：zhanghong19900301@126.com
基金资助:
国家重点研发计划(2021YFC2300200);国家重点研发计划(2020YFC1200100);国家重点研发计划(2018YFA0507202);国家自然科学基金(31825001);国家自然科学基金(81730063);国家自然科学基金(32188101);国家自然科学基金(82102389);国家自然科学基金(81961160737)

Research progress on the effect of human volatiles on mosquito behavior

ZHANG Hong(), CHENG Gong^*()

School of Medicine, Tsinghua University, Beijing 100084, China

Received:2022-11-22 Revised:2023-01-12 Online:2023-02-28 Published:2023-02-03
Contact: * E-mail: gongcheng@mail.tsinghua.edu.cn
Supported by:
National Key Research and Development Plan of China(2021YFC2300200);National Key Research and Development Plan of China(2020YFC1200100);National Key Research and Development Plan of China(2018YFA0507202);National Natural Science Foundation of China(31825001);National Natural Science Foundation of China(81730063);National Natural Science Foundation of China(32188101);National Natural Science Foundation of China(82102389);National Natural Science Foundation of China(81961160737)

摘要/Abstract

摘要：

蚊虫是疟疾、登革热、寨卡热和黄热病等多种蚊媒传染性疾病的传播媒介。蚊虫通过化学感知、热量感知和视觉线索相结合的方式来定位宿主。其中，挥发物是蚊虫识别宿主的关键因素。本文就人体挥发物的来源、影响因素及其对蚊虫行为的影响进行综述，为蚊虫引诱剂及趋避剂的开发提供新的途径。

关键词: 蚊虫, 行为, 挥发物

Abstract:

Mosquitoes are vectors of mosquito-borne infectious diseases such as malaria, dengue, Zika, and yellow fever. Mosquitoes detect the presence of hosts by integrating chemosensory, thermal, and visual cues. Among these, volatiles is crucial for host detection in mosquitoes. In this review, we summarized the sources and factors of human volatiles and their effects on mosquito behavior, which may provide a new approach to the development of mosquito attractants and repellents.

Key words: Mosquitoes, Behavior, Volatiles

中图分类号:

R384.11

张虹, 程功. 人体挥发物对蚊虫行为影响的研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2023, 41(1): 10-14.

ZHANG Hong, CHENG Gong. Research progress on the effect of human volatiles on mosquito behavior[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2023, 41(1): 10-14.

图/表 2

表1

表2

参考文献 50

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释放来源	常见挥发物种类	参考文献
皮肤	羧酸类、羧酸酯类、烷烃类、醛类、酮类、醇类、胺类、卤化物、杂环类、硫化物等	[5,10]
呼吸	饱和烃、不饱和烃、含氧化合物、含硫化合物、含氮化合物等	[11]
尿液	酸类、醇类、酮类、醛类、胺类、挥发物性含硫化合物以及碳氢化合物等。	[9,12-13]
粪便	脂肪族胺，短链脂肪酸，吲哚，苯酚、挥发性含硫化合物等	[9,14]

蚊虫	挥发物	参考文献
埃及伊蚊	氨、L-(+)乳酸、二氯甲烷、乙酸、二甲基硫醚、亚精胺、苯乙酮、二硫化碳、丁酸、3-甲基丁酸、庚酸、十四酸、十六酸、十八酸、苯甲酸、1-己醇、正丁醛、戊醛等	[7,38,43⇓-45]
冈比亚按蚊	氨、1-丁醇、2-甲基-1-丁醇、2-甲基丁醛、2-甲基丁酸、苯乙醇、羧酸类（C3-C8，C14）、2-甲基丁酸甲酯、丁酸丁酯、乙酸丁酯、异丁酸丁酯、二甲基硫醚等	[40,46-47]
致倦库蚊	L-（+）乳酸、乙酸、十六酸、十八酸、二甲基硫醚、丙酸、已酸、庚酸、辛酸、壬酸、癸酸、十一酸、十三酸、十四酸、乙二醇、苯甲醇、胆固醇、庚烯醛、丙醛、壬醛、环戊酮等	[43,48-49]

人体挥发物对蚊虫行为影响的研究进展

Research progress on the effect of human volatiles on mosquito behavior

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