中国寄生虫学与寄生虫病杂志 ›› 2008, Vol. 26 ›› Issue (6): 15-471.

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血吸虫体被的结构功能及其蛋白质组研究

钱门宝,胡薇   

  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2008-12-30 发布日期:2008-12-30

The Structure and Function of Schistosome Tegument and Related Proteomic Study

QIAN Men-bao,HU Wei*   

  • Received:1900-01-01 Revised:1900-01-01 Online:2008-12-30 Published:2008-12-30

摘要: 血吸虫体表由一层合抱体细胞组成,称为体被。体被在血吸虫的营养吸收和免疫逃避等方面发挥重要作用,也被认为是诊断、疫苗和药物的潜在靶点。近年来兴起的体被蛋白质组研究,迄今已发现和鉴定了一大批体被蛋白,这将为血吸虫病的预防控制提供重要线索。

关键词: 血吸虫, 体被, 结构, 功能, 蛋白质组

Abstract: Schistosome is covered by a living syncytium, called tegument, which plays important role in nutrient uptake and immune evasion. Recently, tegumental proteomic research identified lots of proteins, of which there may be potential targets for diagnosis, drugs and vaccines.

Key words: Schistosome, Tegument, Structure, Function, Proteome