中国寄生虫学与寄生虫病杂志

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日本血吸虫色素的形成及其生物学意义

孙军*   

  1. 同济大学医学院传染病与疫苗研究所, 上海 200092
  • 出版日期:2017-08-30 发布日期:2017-09-14

Schistosoma japonicum: hemozoin formation and its biological significance

SUN Jun*   

  1. Institute for Infectious Diseases and Vaccine Development, Tongji University School of Medicine, Shanghai 200092, China
  • Online:2017-08-30 Published:2017-09-14

摘要:

本文总结了日本血吸虫(Schistosoma japonicum)色素的形态结构、形成与分解的特点, 提出血吸虫色素的形成不是红细胞有毒代谢产物血红素的解毒方式, 而是红细胞内血红素铁向虫卵转运的运输方式, 以满足大量虫卵发育过程中对铁的需求这一论点, 并结合当前人们对血吸虫色素形态、形成方式及其生物学意义的认识进行了综述。

关键词: 日本血吸虫, 色素,

Abstract:

By summarizing the characteristics of morphology and structure, formation and degradation of Schistosoma japonicum hemozoin in its gut, this review proposes that the formation of S. japonicum hemozoin is not the way to detoxify toxic heme from metabolisim of hemoglobin, but rather serves to transport iron to eggs to meet the need for iron during egg development. Current understanding of the morphology and formation as well as biological significance of S. japonicum hemozoin are also summarized.

Key words: Schistosoma japonicum, Hemozoin, Iron